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Biology and Biochemistry

D-Index
58
Citations
25392
World Ranking
12888
National Ranking
94

Overview

Anu Kauppinen is affiliated with the University of Eastern Finland in Finland. Their research spans multiple disciplines primarily within Medicine and Biochemistry, Genetics and Molecular Biology. They have a significant number of publications addressing key issues in Ophthalmology and Molecular Biology, with additional work in Immunology, Neurology, and Physiology.

The scientist's work focuses extensively on retinal diseases, neuroinflammation, and immune system mechanisms. Major research topics include:

  • Retinal Diseases and Treatments
  • Inflammasome and Immune Disorders
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Autophagy in Disease and Therapy
  • Heme Oxygenase-1 and Carbon Monoxide
  • Retinal Development and Disorders
  • Ocular Diseases and Behçet's Syndrome

Anu Kauppinen has contributed to a range of scientific papers published in various journals. Notable recent publications include:

  • Mechanisms of mitochondrial dysfunction and their impact on age-related macular degeneration, 2020, Progress in Retinal and Eye Research
  • Photoaging: UV radiation-induced inflammation and immunosuppression accelerate the aging process in the skin, 2022, Inflammation Research
  • ER stress activates immunosuppressive network: implications for aging and Alzheimer's disease, 2020, Journal of Molecular Medicine
  • Insulin/IGF-1 signaling promotes immunosuppression via the STAT3 pathway: impact on the aging process and age-related diseases, 2021, Inflammation Research
  • Mitophagy in the Retinal Pigment Epithelium of Dry Age-Related Macular Degeneration Investigated in the NFE2L2/PGC-1α-/- Mouse Model, 2020, International Journal of Molecular Sciences

The frequent co-authors working alongside Anu Kauppinen include:

  • Kai Kaarniranta
  • Maria Hytti
  • Niina Bhattarai
  • Antero Salminen
  • Eveliina Korhonen

In terms of publication venues, Anu Kauppinen has commonly published in:

  • Acta Ophthalmologica
  • International Journal of Molecular Sciences
  • Antioxidants
  • Inflammation Research
  • Cells

This profile outlines a research career focused on understanding the molecular and immunological foundations of ocular and age-related diseases. The combination of neuroscience, immunology, and molecular biology perspectives is reflected in a diverse set of collaborations and publication records. The focus on retinal health and aging highlights the intersection of clinical and basic science approaches in Anu Kauppinen's work.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders.

    Anu Kauppinen;Tiina Suuronen;Johanna Ojala;Kai Kaarniranta

  • Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP).

    Antero Salminen;Anu Kauppinen;Kai Kaarniranta

  • Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging.

    Antero Salminen;Jari Huuskonen;Johanna Ojala;Anu Kauppinen

  • Inflammation and its role in age-related macular degeneration

    Anu Kauppinen;Jussi J. Paterno;Janusz Blasiak;Antero Salminen

  • Inflammaging: disturbed interplay between autophagy and inflammasomes

    Antero Salminen;Kai Kaarniranta;Anu Kauppinen

  • Crosstalk between Oxidative Stress and SIRT1: Impact on the Aging Process.

    Antero Salminen;Kai Kaarniranta;Anu Kauppinen

  • Inflammation in Alzheimer's disease: Amyloid-β oligomers trigger innate immunity defence via pattern recognition receptors

    Antero Salminen;Johanna Ojala;Anu Kauppinen;Kai Kaarniranta

  • ER stress in Alzheimer's disease: a novel neuronal trigger for inflammation and Alzheimer's pathology

    Antero Salminen;Anu Kauppinen;Tiina Suuronen;Kai Kaarniranta

  • Impaired autophagy and APP processing in Alzheimer's disease: The potential role of Beclin 1 interactome.

    Antero Salminen;Kai Kaarniranta;Anu Kauppinen;Johanna Ojala

  • Mechanisms of mitochondrial dysfunction and their impact on age-related macular degeneration

    Kai Kaarniranta;Hannu Uusitalo;Janusz Blasiak;Szabolcs Felszeghy

  • Clusterin: A forgotten player in Alzheimer's disease

    Tapio Nuutinen;Tiina Suuronen;Anu Kauppinen;Antero Salminen

  • Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration

    Kai Kaarniranta;Debasish Sinha;Janusz Blasiak;Anu Kauppinen

  • Mitochondrial dysfunction and oxidative stress activate inflammasomes: impact on the aging process and age-related diseases

    Antero Salminen;Johanna Ojala;Kai Kaarniranta;Anu Kauppinen

  • Oxidative stress activates NLRP3 inflammasomes in ARPE-19 cells--implications for age-related macular degeneration (AMD).

    Anu Kauppinen;Henri Niskanen;Tiina Suuronen;Kati Kinnunen

  • SIRT1 longevity factor suppresses NF-κB -driven immune responses: regulation of aging via NF-κB acetylation?

    Antero Salminen;Anu Kauppinen;Tiina Suuronen;Kai Kaarniranta;Kai Kaarniranta

  • Amyloid‐β oligomers set fire to inflammasomes and induce Alzheimer's pathology

    Antero Salminen;Johanna Ojala;Tiina Suuronen;Kai Kaarniranta

  • Hypoxia/ischemia activate processing of Amyloid Precursor Protein: impact of vascular dysfunction in the pathogenesis of Alzheimer's disease.

    Antero Salminen;Anu Kauppinen;Kai Kaarniranta

  • Age-related changes in AMPK activation: Role for AMPK phosphatases and inhibitory phosphorylation by upstream signaling pathways

    Antero Salminen;Kai Kaarniranta;Anu Kauppinen

  • Beclin 1 interactome controls the crosstalk between apoptosis, autophagy and inflammasome activation: impact on the aging process.

    Antero Salminen;Kai Kaarniranta;Anu Kauppinen

Frequent Co-Authors

Kai Kaarniranta
Kai Kaarniranta University of Eastern Finland
Antero Salminen
Antero Salminen University of Eastern Finland
Janusz Blasiak
Janusz Blasiak University of Łódź
Arto Urtti
Arto Urtti University of Eastern Finland
Mikko Hiltunen
Mikko Hiltunen University of Eastern Finland
Deborah A. Ferrington
Deborah A. Ferrington University of Minnesota
Paavo Honkakoski
Paavo Honkakoski University of Eastern Finland
Heli Skottman
Heli Skottman Tampere University
Heping Xu
Heping Xu Queen's University Belfast
Anna-Liisa Levonen
Anna-Liisa Levonen University of Eastern Finland

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