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Deborah A. Ferrington

Deborah A. Ferrington

D-Index & Metrics

Biology and Biochemistry

D-Index
47
Citations
8863
World Ranking
18672
National Ranking
7633

Overview

Deborah A. Ferrington is affiliated with the University of Minnesota in the United States and has contributed extensively to the fields of medicine and biochemistry, genetics, and molecular biology. Their research primarily focuses on retinal diseases, retinal development, and mitochondrial function, with significant intersections in ophthalmology and radiology-related disciplines.

The scientist has published research concentrated on topics including:

  • Retinal Diseases and Treatments
  • Retinal Development and Disorders
  • Retinal Imaging and Analysis
  • Autophagy in Disease and Therapy
  • Ocular Diseases and Behçet's Syndrome
  • Mosquito-borne diseases and control
  • Mitochondrial Function and Pathology

Notable recent papers by Deborah A. Ferrington include:

  • "Mechanisms of mitochondrial dysfunction and their impact on age-related macular degeneration," 2020, published in Progress in Retinal and Eye Research
  • "Glutathione Metabolism and the Novel Role of Mitochondrial GSH in Retinal Degeneration," 2021, published in Antioxidants
  • "Improving retinal mitochondrial function as a treatment for age-related macular degeneration," 2020, published in Redox Biology
  • "Impaired Mitochondrial Function in iPSC-Retinal Pigment Epithelium with the Complement Factor H Polymorphism for Age-Related Macular Degeneration," 2021, published in Cells
  • "Family-based exome sequencing identifies rare coding variants in age-related macular degeneration," 2020, published in Human Molecular Genetics

The scientist frequently collaborates with other researchers in their field, including Sandra R. Montezuma, Rebecca J. Kapphahn, Mara C. Ebeling, Zhaohui Geng, and James R. Dutton. These recurring co-authorships reflect ongoing partnerships in advancing research on retinal and mitochondrial biology.

Deborah A. Ferrington has published multiple articles in several prominent venues such as:

  • Experimental Eye Research
  • Zenodo (CERN European Organization for Nuclear Research)
  • Antioxidants
  • Nature Communications
  • Cells

Their work covers subfields including molecular biology, ophthalmology, radiology, nuclear medicine, imaging, epidemiology, and immunology, indicating a multidisciplinary approach to understanding ocular and mitochondrial diseases.

Best Publications

  • Immunoproteasomes: structure, function, and antigen presentation.

    Deborah A. Ferrington;Dale S. Gregerson

  • Mechanisms of mitochondrial dysfunction and their impact on age-related macular degeneration

    Kai Kaarniranta;Hannu Uusitalo;Janusz Blasiak;Szabolcs Felszeghy

  • Protein modification during biological aging: selective tyrosine nitration of the SERCA2a isoform of the sarcoplasmic reticulum Ca2+-ATPase in skeletal muscle.

    Rosa I. Viner;Deborah A. Ferrington;Todd D. Williams;Diana J. Bigelow

  • Altered proteasome structure, function, and oxidation in aged muscle.

    Deborah A. Ferrington;Aimee D. Husom;La Dora V. Thompson

  • Retinal transcriptome and eQTL analyses identify genes associated with age-related macular degeneration

    Rinki Ratnapriya;Olukayode A. Sosina;Olukayode A. Sosina;Margaret R. Starostik;Madeline Kwicklis

  • Mitochondrial DNA damage as a potential mechanism for age-related macular degeneration.

    Pabalu P. Karunadharma;Curtis L. Nordgaard;Timothy W. Olsen;Deborah A. Ferrington

  • Defects in retinal pigment epithelial cell proteolysis and the pathology associated with age-related macular degeneration.

    Deborah A. Ferrington;Debasish Sinha;Kai Kaarniranta

  • Diastereoselective reduction of protein-bound methionine sulfoxide by methionine sulfoxide reductase.

    Victor S. Sharov;Deborah A. Ferrington;Thomas C. Squier;Christian Schöneich

  • Investigating Mitochondria as a Target for Treating Age-Related Macular Degeneration

    Marcia R. Terluk;Rebecca J. Kapphahn;Lauren M. Soukup;Hwee Gong

  • Altered proteasome function and subunit composition in aged muscle.

    Aimee D. Husom;Elizabeth A. Peters;Erin A. Kolling;Nicole A. Fugere

  • Mitochondrial proteomics of the retinal pigment epithelium at progressive stages of age-related macular degeneration.

    Curtis L. Nordgaard;Pabalu P. Karunadharma;Xiao Feng;Timothy W. Olsen

  • Perspective on AMD Pathobiology: A Bioenergetic Crisis in the RPE

    Cody R. Fisher;Deborah A. Ferrington

  • Accumulation of nitrotyrosine on the SERCA2a isoform of SR Ca-ATPase of rat skeletal muscle during aging: a peroxynitrite-mediated process?

    Rosa I. Viner;Deborah A. Ferrington;Andreas F.R. Hühmer;Diana J. Bigelow

  • Repair of oxidized calmodulin by methionine sulfoxide reductase restores ability to activate the plasma membrane Ca-ATPase.

    Hongye Sun;Jun Gao;Deborah A. Ferrington;Homigol Biesiada

  • Covalent Modification of Epithelial Fatty Acid-binding Protein by 4-Hydroxynonenal in Vitro and in Vivo EVIDENCE FOR A ROLE IN ANTIOXIDANT BIOLOGY

    Assumpta Bennaars-Eiden;Lee Ann Higgins;Ann V. Hertzel;Rebecca J. Kapphahn

  • Changes in select redox proteins of the retinal pigment epithelium in age-related macular degeneration.

    Alejandra Decanini;Curtis L. Nordgaard;Xiao Feng;Deborah A. Ferrington

  • Catalytic site‐specific inhibition of the 20S proteasome by 4‐hydroxynonenal

    Deborah A. Ferrington;Rebecca J. Kapphahn

  • Proteomics of the retinal pigment epithelium reveals altered protein expression at progressive stages of age-related macular degeneration.

    Curtis L. Nordgaard;Kristin M. Berg;Rebecca J. Kapphahn;Cavan Reilly

  • Altered bioenergetics and enhanced resistance to oxidative stress in human retinal pigment epithelial cells from donors with age-related macular degeneration.

    Deborah A. Ferrington;Mara C. Ebeling;Rebecca J. Kapphahn;Marcia R. Terluk

  • Proteasome function and protein oxidation in the aged retina.

    Jennifer L. Louie;Rebecca J. Kapphahn;Deborah A. Ferrington

Frequent Co-Authors

Anand Swaroop
Anand Swaroop National Institutes of Health
Kai Kaarniranta
Kai Kaarniranta University of Eastern Finland
Gonçalo R. Abecasis
Gonçalo R. Abecasis University of Michigan–Ann Arbor
Lars G. Fritsche
Lars G. Fritsche University of Michigan–Ann Arbor
Emily Y. Chew
Emily Y. Chew National Institutes of Health
Anu Kauppinen
Anu Kauppinen University of Eastern Finland
Christian Schöneich
Christian Schöneich University of Kansas
Cavan S. Reilly
Cavan S. Reilly University of Minnesota
Steven J. Fliesler
Steven J. Fliesler University at Buffalo, State University of New York
Machelle T. Pardue
Machelle T. Pardue Georgia Institute of Technology

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