Biochemistry, Methionine sulfoxide reductase, Methionine, Methionine sulfoxide and MSRA are his primary areas of study. His studies deal with areas such as Sulfoxide and Nitric oxide as well as Biochemistry. His work carried out in the field of Methionine sulfoxide reductase brings together such families of science as Apolipoprotein B, Reactive oxygen species, Escherichia coli, Molecular biology and Cysteine.
His research integrates issues of Apoptosis, Complement C1q and Gene in his study of Molecular biology. The concepts of his Methionine study are interwoven with issues in Regulation of gene expression, Redox, Cholesterol and Potassium channel. His study in MSRA is interdisciplinary in nature, drawing from both Oxidative stress and Mutant.
Nathan Brot mainly focuses on Biochemistry, Molecular biology, Escherichia coli, Methionine and Methionine sulfoxide reductase. His research in Methionine sulfoxide, Enzyme, MSRA, Ribosomal protein and Ribosome are components of Biochemistry. His Methionine sulfoxide research focuses on subjects like Peptide sequence, which are linked to Amino acid.
His Molecular biology research includes elements of In vitro and RNA, RNA polymerase, Gene expression, Gene. Nathan Brot works in the field of Methionine, namely Methionine synthase. Nathan Brot combines subjects such as Thioredoxin, Reactive oxygen species and Cysteine with his study of Methionine sulfoxide reductase.
His scientific interests lie mostly in Biochemistry, Methionine sulfoxide reductase, MSRA, Methionine and Methionine sulfoxide. His Biochemistry research focuses on Stereochemistry and how it connects with Organic chemistry. Nathan Brot interconnects Molecular biology, Disulfide bond and Ferredoxin-thioredoxin reductase in the investigation of issues within Methionine sulfoxide reductase.
The study incorporates disciplines such as Cysteine, Metallothionein and Escherichia coli in addition to MSRA. His work deals with themes such as Endocrinology, Internal medicine, Cholesterol, Apolipoprotein B and Bacteria, which intersect with Methionine. In Methionine sulfoxide, Nathan Brot works on issues like Methionine synthase, which are connected to Antioxidant.
His primary areas of investigation include Biochemistry, Methionine sulfoxide reductase, Methionine, MSRA and Methionine sulfoxide. In general Biochemistry, his work in TBARS is often linked to 8-Hydroxy-2'-deoxyguanosine and Neuroprostanes linking many areas of study. His research in Methionine sulfoxide reductase intersects with topics in Apoptosis, Mitochondrion, Inner mitochondrial membrane, Cell biology and Molecular biology.
His studies in Methionine integrate themes in fields like Internal medicine, Cholesterol and Apolipoprotein B. His MSRA research also works with subjects such as
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C-Reactive Protein Binds to Apoptotic Cells, Protects the Cells from Assembly of the Terminal Complement Components, and Sustains an Antiinflammatory Innate Immune Response
Debra Gershov;SunJung Kim;Nathan Brot;Keith B. Elkon.
Journal of Experimental Medicine (2000)
Biomarkers of oxidative stress study II : are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning?
M.B. Kadiiska;B.C. Gladen;D.D. Baird;D. Germolec.
Free Radical Biology and Medicine (2005)
Association between lupus psychosis and anti-ribosomal P protein antibodies.
Eloisa Bonfa;Steven J. Golombek;Lee D. Kaufman;Susan Skelly.
The New England Journal of Medicine (1987)
High-quality life extension by the enzyme peptide methionine sulfoxide reductase
Hongyu Ruan;Xiang Dong Tang;Mai-Lei Chen;Mei-Ling A. Joiner.
Proceedings of the National Academy of Sciences of the United States of America (2002)
I-PLA2 Activation during Apoptosis Promotes the Exposure of Membrane Lysophosphatidylcholine Leading to Binding by Natural Immunoglobulin M Antibodies and Complement Activation
Sun Jun Kim;Debra Gershov;Xiaojing Ma;Nathan Brot.
Journal of Experimental Medicine (2002)
ENZYMATIC REDUCTION OF PROTEIN-BOUND METHIONINE SULFOXIDE
Nathan Brot;Lawrence Weissbach;Jean Werth;Herbert Weissbach.
Proceedings of the National Academy of Sciences of the United States of America (1981)
Escherichia coli peptide methionine sulfoxide reductase gene: regulation of expression and role in protecting against oxidative damage.
J Moskovitz;M A Rahman;J Strassman;S O Yancey.
Journal of Bacteriology (1995)
Biochemistry and physiological role of methionine sulfoxide residues in proteins
Nathan Brot;Herbert Weissbach.
Archives of Biochemistry and Biophysics (1983)
Peptide methionine sulfoxide reductase: structure, mechanism of action, and biological function
Herbert Weissbach;Frantzy Etienne;Toshinori Hoshi;Stefan H. Heinemann.
Archives of Biochemistry and Biophysics (2002)
Methionine sulfoxide reductases: history and cellular role in protecting against oxidative damage.
Herbert Weissbach;Lionel Resnick;Nathan Brot.
Biochimica et Biophysica Acta (2005)
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