D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 57 Citations 10,232 105 World Ranking 2006 National Ranking 982

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Antibody

Keith B. Elkon spends much of his time researching Immunology, Apoptosis, Fas receptor, Antigen and Molecular biology. His Immunology study frequently links to related topics such as Systemic lupus erythematosus. He works mostly in the field of Apoptosis, limiting it down to topics relating to Autoimmunity and, in certain cases, Phagocytosis and Immunoglobulin G.

His Fas receptor research includes elements of Phenotype, Fas ligand, CD8 and Mutation. His research in Antigen intersects with topics in Autoantibody and Graft-versus-host disease. His work deals with themes such as Fetus, Reverse transcriptase, Northern blot and Cell biology, which intersect with Molecular biology.

His most cited work include:

  • Systemic vasculitis with asthma and eosinophilia: a clinical approach to the Churg-Strauss syndrome (961 citations)
  • Complement-dependent Clearance of Apoptotic Cells by Human Macrophages (601 citations)
  • C-Reactive Protein Binds to Apoptotic Cells, Protects the Cells from Assembly of the Terminal Complement Components, and Sustains an Antiinflammatory Innate Immune Response (590 citations)

What are the main themes of his work throughout his whole career to date?

Keith B. Elkon focuses on Immunology, Antibody, Autoantibody, Molecular biology and Apoptosis. Immunology is often connected to Systemic lupus erythematosus in his work. His Antibody study integrates concerns from other disciplines, such as Internal medicine, Gel electrophoresis and Ribosomal protein.

The Autoantibody study combines topics in areas such as Subclass, Counterimmunoelectrophoresis, Epitope, Antigen and Anti-SSA/Ro autoantibodies. His Molecular biology research integrates issues from Complementary DNA, Amino acid and Peptide sequence. Keith B. Elkon has researched Apoptosis in several fields, including Cancer research and Signal transduction.

He most often published in these fields:

  • Immunology (69.77%)
  • Antibody (44.96%)
  • Autoantibody (37.98%)

What were the highlights of his more recent work (between 1998-2008)?

  • Apoptosis (27.13%)
  • Immunology (69.77%)
  • Fas receptor (20.93%)

In recent papers he was focusing on the following fields of study:

Keith B. Elkon mostly deals with Apoptosis, Immunology, Fas receptor, Autoimmunity and Cancer research. His study in Apoptosis is interdisciplinary in nature, drawing from both Signal transduction, Cell biology and Complement system. His Immunology and Autoantibody, B cell, Autoimmune disease, Immune system and Adoptive cell transfer investigations all form part of his Immunology research activities.

His Autoantibody study combines topics in areas such as Spleen, Lupus erythematosus and Pathology. His Lupus erythematosus research includes themes of Systemic lupus erythematosus and Endocrinology. His research investigates the link between Fas receptor and topics such as Death domain that cross with problems in FADD.

Between 1998 and 2008, his most popular works were:

  • C-Reactive Protein Binds to Apoptotic Cells, Protects the Cells from Assembly of the Terminal Complement Components, and Sustains an Antiinflammatory Innate Immune Response (590 citations)
  • Impaired Fas response and autoimmunity in Pten+/- mice (485 citations)
  • The molecular basis for apoptotic defects in patients with CD95 (Fas/Apo-1) mutations (156 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Antibody

The scientist’s investigation covers issues in Cytokine, Apoptosis, Cell biology, Innate immune system and Immunology. The various areas that Keith B. Elkon examines in his Apoptosis study include Cancer research and Signal transduction. His work carried out in the field of Signal transduction brings together such families of science as Tumor suppressor gene and Autoimmune disease.

His Cell biology study combines topics from a wide range of disciplines, such as Fas ligand, Complement component 3, Classical complement pathway, Inhibitor of apoptosis and Complement membrane attack complex. His Innate immune system research incorporates elements of Acquired immune system, Tumor necrosis factor alpha, Immunity, Defective virus and Adoptive cell transfer. His research investigates the connection with Immunology and areas like Cytotoxic T cell which intersect with concerns in Autoimmunity.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Systemic vasculitis with asthma and eosinophilia: a clinical approach to the Churg-Strauss syndrome

John G. Lanham;Keith B. Elkon;Charles D. Pusey;Graham R. Hughes.
Medicine (1984)

1520 Citations

Complement-dependent Clearance of Apoptotic Cells by Human Macrophages

Dror Mevorach;John O. Mascarenhas;Debra Gershov;Keith B. Elkon.
Journal of Experimental Medicine (1998)

942 Citations

C-Reactive Protein Binds to Apoptotic Cells, Protects the Cells from Assembly of the Terminal Complement Components, and Sustains an Antiinflammatory Innate Immune Response

Debra Gershov;SunJung Kim;Nathan Brot;Keith B. Elkon.
Journal of Experimental Medicine (2000)

908 Citations

SYSTEMIC EXPOSURE TO IRRADIATED APOPTOTIC CELLS INDUCES AUTOANTIBODY PRODUCTION

Dror Mevorach;Jun Liang Zhou;Xin Song;Keith B. Elkon.
Journal of Experimental Medicine (1998)

843 Citations

Fas gene mutations in the Canale-Smith syndrome, an inherited lymphoproliferative disorder associated with autoimmunity.

Jörn Drappa;Akshay K. Vaishnaw;Kathleen E. Sullivan;Jia Li Chu.
The New England Journal of Medicine (1996)

662 Citations

Impaired Fas response and autoimmunity in Pten+/- mice

Antonio Di Cristofano;Paraskevi Kotsi;Yu Feng Peng;Carlos Cordon-Cardo.
Science (1999)

637 Citations

The defect in Fas mRNA expression in MRL/lpr mice is associated with insertion of the retrotransposon, ETn.

Jia Li Chu;Jorn Drappa;Andrew Parnassa;Keith B. Elkon.
Journal of Experimental Medicine (1993)

333 Citations

CD40 ligation induces apo-1/fas expression on human B lymphocytes and facilitates apoptosis through the apo-1/fas pathway

Elaine J. Schattner;Keith B. Elkon;Dae Hyun Yoo;Joseph Tumang.
Journal of Experimental Medicine (1995)

315 Citations

The Fas protein is expressed at high levels on CD4+CD8+ thymocytes and activated mature lymphocytes in normal mice but not in the lupus-prone strain, MRL lpr/lpr.

Jorn Drappa;Nathan Brot;Keith B. Elkon.
Proceedings of the National Academy of Sciences of the United States of America (1993)

284 Citations

The apoptosis-1/Fas protein in human systemic lupus erythematosus.

Eduardo Mysler;Paolo Bini;Jörn Drappa;Paula Ramos.
Journal of Clinical Investigation (1994)

274 Citations

Best Scientists Citing Keith B. Elkon

Yehuda Shoenfeld

Yehuda Shoenfeld

Sheba Medical Center

Publications: 50

Jill P. Buyon

Jill P. Buyon

New York University

Publications: 42

Martin Herrmann

Martin Herrmann

University of Erlangen-Nuremberg

Publications: 40

John D. Mountz

John D. Mountz

University of Alabama at Birmingham

Publications: 37

Loïc Guillevin

Loïc Guillevin

Université Paris Cité

Publications: 33

Pier Paolo Pandolfi

Pier Paolo Pandolfi

Beth Israel Deaconess Medical Center

Publications: 31

Michael J. Lenardo

Michael J. Lenardo

National Institutes of Health

Publications: 31

Sharon E. Straus

Sharon E. Straus

University of Toronto

Publications: 29

Mark Walport

Mark Walport

Wellcome Trust

Publications: 28

Frédéric Rieux-Laucat

Frédéric Rieux-Laucat

Imagine Institute of Genetic Diseases

Publications: 28

Jennifer M. Puck

Jennifer M. Puck

University of California, San Francisco

Publications: 27

Hideo Yagita

Hideo Yagita

Juntendo University

Publications: 27

John B. Harley

John B. Harley

Cincinnati Children's Hospital Medical Center

Publications: 26

Alberto Mantovani

Alberto Mantovani

Humanitas University

Publications: 26

Peter H. Krammer

Peter H. Krammer

German Cancer Research Center

Publications: 25

Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking d-index is inferred from publications deemed to belong to the considered discipline.

If you think any of the details on this page are incorrect, let us know.

Contact us
Something went wrong. Please try again later.