World's Best Scientists 2026 revealed!
Erik Falck-Pedersen

Erik Falck-Pedersen

D-Index & Metrics

Biology and Biochemistry

D-Index
43
Citations
7094
World Ranking
19401
National Ranking
7918

Overview

Erik Falck-Pedersen is affiliated with Cornell University in the United States. Their research spans several interconnected fields, primarily within biochemistry, genetics, molecular biology, and medicine. The scientist's work is particularly focused on molecular biology, oncology, neurology, cancer research, and genetics.

The recent papers authored or co-authored by Erik Falck-Pedersen illustrate a range of topics in their research portfolio. These include:

  • ADAM17 stabilizes its interacting partner inactive Rhomboid 2 (iRhom2) but not inactive Rhomboid 1 (iRhom1), 2020, Journal of Biological Chemistry
  • E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes, 2020, Proceedings of the National Academy of Sciences
  • Reciprocal impacts of telomerase activity and ADRN/MES differentiation state in neuroblastoma tumor biology, 2021, Communications Biology
  • Reciprocal impacts of telomerase activity and tumor cell differentiation in neuroblastoma tumor biology, 2021, bioRxiv (Cold Spring Harbor Laboratory)

Erik Falck-Pedersen collaborates frequently with several researchers, reflecting a collaborative approach to scientific inquiry. Frequent co-authors include:

  • Eun Young Yu
  • Syed Zahid
  • Sarah Aloe
  • Xi Kathy Zhou
  • Nai-Kong V. Cheung

The publication venues where their work appears underline an engagement with recognized scientific journals and repositories in biomedical research. These venues include:

  • Journal of Biological Chemistry
  • Proceedings of the National Academy of Sciences
  • Communications Biology
  • bioRxiv (Cold Spring Harbor Laboratory)

The main topics covered in Erik Falck-Pedersen's research involve complex biological mechanisms and disease processes. Key research topics can be summarized as:

  • Neuroblastoma Research and Treatments
  • Mitochondrial Function and Pathology
  • Cancer, Hypoxia, and Metabolism
  • Signaling Pathways in Disease
  • Peptidase Inhibition and Analysis
  • HER2/EGFR in Cancer Research
  • Virus-based gene therapy research

This diverse range of topics aligns with their contributions across multiple subfields, reflecting an integrated approach to understanding disease mechanisms at the molecular and cellular levels.

Best Publications

  • Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration

    Stefan Worgall;Gerhard Wolff;Erik Falck-Pedersen;Ronald G. Crystal

  • Adenovirus Type 5 and 7 Capsid Chimera: Fiber Replacement Alters Receptor Tropism without Affecting Primary Immune Neutralization Epitopes

    J Gall;A Kass-Eisler;L Leinwand;E Falck-Pedersen

  • A poly(A) addition site and a downstream termination region are required for efficient cessation of transcription by RNA polymerase II in the mouse beta maj-globin gene.

    John Logan;Erik Falck-Pedersen;James E. Darnell;Thomas Shenk

  • “Sero-Switch” Adenovirus-Mediated In Vivo Gene Transfer: Circumvention of Anti-Adenovirus Humoral Immune Defenses Against Repeat Adenovirus Vector Administration by Changing the Adenovirus Serotype

    Andrea Mastrangeli;Ben-Gary Harvey;Jeffrey Yao;Gerhard Wolff

  • Quantitative determination of adenovirus-mediated gene delivery to rat cardiac myocytes in vitro and in vivo

    Alyson Kass-Eisler;Erik Falck-Pedersen;Mauricio Alvira;Johanna Rivera

  • Sensitization of IFN-gamma Jak-STAT signaling during macrophage activation.

    Xiaoyu Hu;Carmen Herrero;Wai-Ping Li;Taras T Antoniv

  • TNF-α-dependent maturation of local dendritic cells is critical for activating the adaptive immune response to virus infection

    Jose M. Trevejo;Michael W. Marino;Nicola Philpott;Regis Josien

  • The impact of developmental stage, route of administration and the immune system on adenovirus-mediated gene transfer.

    A Kass-Eisler;E Falck-Pedersen;D H Elfenbein;M Alvira

  • Fiber swap between adenovirus subgroups B and C alters intracellular trafficking of adenovirus gene transfer vectors.

    Naoki Miyazawa;Philip L. Leopold;Neil R. Hackett;Barbara Ferris

  • Adenovirus Detection by the cGAS/STING/TBK1 DNA Sensing Cascade

    Eric Lam;Saskia Stein;Erik Falck-Pedersen

  • Construction and Characterization of Hexon-Chimeric Adenoviruses: Specification of Adenovirus Serotype

    Jason G. D. Gall;Ronald G. Crystal;Erik Falck-Pedersen

  • Circumventing the immune response to adenovirus-mediated gene therapy.

    A Kass-Eisler;L Leinwand;J Gall;B Bloom

  • Tumor necrosis factor α plays a central role in immune-mediated clearance of adenoviral vectors

    Keith B. Elkon;Chau Ching Liu;Jason G. Gall;Jose Trevejo

  • Sensing Infection by Adenovirus: Toll-Like Receptor-Independent Viral DNA Recognition Signals Activation of the Interferon Regulatory Factor 3 Master Regulator

    Marcelo Nociari;Oksana Ocheretina;John W. Schoggins;Erik Falck-Pedersen

  • Adenovirale vektoren, die nicht von gruppe c adenovirus typen abgeleitet sind

    Karil Abrahamsen;G. Ronald Potomac Crystal;S. Erik Dobbs Ferry Falck-Pedersen;Andrea New York Mastrangeli

  • Adenovirus-induced maturation of dendritic cells through a PI3 kinase-mediated TNF-α induction pathway

    Nicola J. Philpott;Marcelo Nociari;Keith B. Elkon;Erik Falck-Pedersen

  • Chimeric adenovirus fiber protein

    Thomas J. Wickham;Erik Falck-Pedersen;Petrus W. Roelvink;Joseph T. Bruder

  • A p5 integration efficiency element mediates Rep-dependent integration into AAVS1 at chromosome 19

    Nicola J. Philpott;Janette Gomos;Kenneth I. Berns;Erik Falck-Pedersen

  • Modification of the genetic program of human alveolar macrophages by adenovirus vectors in vitro is feasible but inefficient, limited in part by the low level of expression of the coxsackie/adenovirus receptor.

    Robert J. Kaner;Stefan Worgall;Philip L. Leopold;Eric Stolze

  • Transcription termination within the E1A gene of adenovirus induced by insertion of the mouse β-major globin terminator element

    E. Falck-Pedersen;J. Logan;Thomas Eugene Shenk;J. E. Darnell

Frequent Co-Authors

Ronald G. Crystal
Ronald G. Crystal Cornell University
John W. Schoggins
John W. Schoggins The University of Texas Southwestern Medical Center
Eric Lam
Eric Lam Sun Yat-sen University
Leslie A. Leinwand
Leslie A. Leinwand University of Colorado Boulder
Michel Sadelain
Michel Sadelain Columbia University
James E. Darnell
James E. Darnell Rockefeller University
Thiago Y. Oliveira
Thiago Y. Oliveira Rockefeller University
Enrique Rodriguez-Boulan
Enrique Rodriguez-Boulan Cornell University
Kenneth I. Berns
Kenneth I. Berns University of Florida
Keith B. Elkon
Keith B. Elkon University of Washington

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