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Molecular Biology
USA
2026
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Genetics and Molecular Biology
USA
2024

D-Index & Metrics

Molecular Biology

D-Index
154
Citations
106258
World Ranking
74
National Ranking
47

James E. Darnell publication distribution in Molecular Biology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Molecular Biology in 2026. The highlighted bar marks where James E. Darnell sits on this spectrum.

47–56 publications: 7 scientists 57–66 publications: 17 scientists 67–76 publications: 65 scientists 77–86 publications: 90 scientists 87–96 publications: 125 scientists 97–106 publications: 131 scientists 107–116 publications: 162 scientists 117–126 publications: 177 scientists 127–136 publications: 158 scientists 137–146 publications: 158 scientists 147–156 publications: 146 scientists 157–166 publications: 159 scientists 167–176 publications: 131 scientists 177–186 publications: 110 scientists 187–196 publications: 112 scientists 197–206 publications: 100 scientists 207–216 publications: 89 scientists 217–226 publications: 98 scientists 227–236 publications: 74 scientists 237–246 publications: 72 scientists 247–256 publications: 63 scientists 257–266 publications: 53 scientists 267–276 publications: 54 scientists 277–286 publications: 49 scientists 287–296 publications: 52 scientists 297–306 publications: 43 scientists 307–316 publications: 46 scientists 317–326 publications: 41 scientists 327–336 publications: 42 scientists 337–346 publications: 31 scientists 347–356 publications: 28 scientists 357–366 publications: 29 scientists 367–376 publications: 26 scientists 377–386 publications: 24 scientists 387–396 publications: 24 scientists 397–406 publications: 14 scientists 407–416 publications: 13 scientists 417–426 publications: 20 scientists 427–436 publications: 12 scientists 437–446 publications: 20 scientists 447–456 publications: 11 scientists 457–466 publications: 10 scientists 467–476 publications: 14 scientists 477–486 publications: 14 scientists 487–496 publications: 10 scientists 497–506 publications: 13 scientists 507–516 publications: 13 scientists 517–526 publications: 2 scientists 527–536 publications: 4 scientists 537–546 publications: 6 scientists 547–556 publications: 8 scientists 557–563 publications: 6 scientists 564+ publications: 100 scientists
47 publications 564+

This scientist: 330 publications — 85th percentile

85% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 564 publications or more.

James E. Darnell D-index placement in Molecular Biology in 2026

The chart shows the D-index (discipline H-index) distribution of Molecular Biology scientists ranked by Research.com in 2026. The highlighted bar marks where James E. Darnell sits on this spectrum.

40–41 D-Index: 36 scientists 42–43 D-Index: 101 scientists 44–45 D-Index: 115 scientists 46–47 D-Index: 121 scientists 48–49 D-Index: 118 scientists 50–51 D-Index: 130 scientists 52–53 D-Index: 106 scientists 54–55 D-Index: 116 scientists 56–57 D-Index: 113 scientists 58–59 D-Index: 129 scientists 60–61 D-Index: 120 scientists 62–63 D-Index: 105 scientists 64–65 D-Index: 131 scientists 66–67 D-Index: 95 scientists 68–69 D-Index: 97 scientists 70–71 D-Index: 106 scientists 72–73 D-Index: 83 scientists 74–75 D-Index: 89 scientists 76–77 D-Index: 77 scientists 78–79 D-Index: 70 scientists 80–81 D-Index: 73 scientists 82–83 D-Index: 60 scientists 84–85 D-Index: 48 scientists 86–87 D-Index: 45 scientists 88–89 D-Index: 50 scientists 90–91 D-Index: 31 scientists 92–93 D-Index: 51 scientists 94–95 D-Index: 43 scientists 96–97 D-Index: 38 scientists 98–99 D-Index: 39 scientists 100–101 D-Index: 41 scientists 102–103 D-Index: 29 scientists 104–105 D-Index: 33 scientists 106–107 D-Index: 35 scientists 108–109 D-Index: 20 scientists 110–111 D-Index: 38 scientists 112–113 D-Index: 19 scientists 114–115 D-Index: 28 scientists 116–117 D-Index: 13 scientists 118–119 D-Index: 23 scientists 120–121 D-Index: 16 scientists 122–123 D-Index: 15 scientists 124–125 D-Index: 11 scientists 126–127 D-Index: 21 scientists 128–129 D-Index: 7 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 14 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 9 scientists 138–139 D-Index: 8 scientists 140–141 D-Index: 16 scientists 142–143 D-Index: 7 scientists 144 D-Index: 7 scientists 145+ D-Index: 100 scientists
40 D-Index 145+

This scientist: 154 D-Index — 98th percentile

98% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 145 D-Index or more.

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in United States Leader Award
  • 2025 - Research.com Molecular Biology in United States Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in United States Leader Award
  • 2023 - Research.com Molecular Biology in United States Leader Award
  • 2002 - US President's National Medal of Science "For his seminal scientific discoveries related to gene expression in animal cells, including pathways of RNA processing and signal transduction from the cell surface to genes in the nucleus, and for his contributions as a scientific educator", Presented by President George W. Bush in a White House East Room ceremony on November 6, 2003.
  • 1998 - E.B. Wilson Medal, American Society for Cell Biology
  • 1996 - Fellow of the Royal Society, United Kingdom
  • 1991 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1986 - Canada Gairdner International Award
  • 1973 - Fellow of the American Academy of Arts and Sciences
  • 1963 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

James E. Darnell is affiliated with Rockefeller University in the United States. Their research spans multiple fields, including Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. The main subfields of study in their work include Immunology, Molecular Biology, Oncology, and Epidemiology.

The scientific topics covered by Darnell's research focus on Cytokine Signaling Pathways and Interactions, interferon and immune responses, Mycobacterium research and diagnosis, RNA Interference and Gene Delivery, Immunotherapy and Immune Responses, and Genomics and Chromatin Dynamics.

Darnell has published in notable venues including Cell and Molecular Therapy Oncology. Their recent publications include:

  • "The JAK-STAT pathway at 30: Much learned, much more to do" (2022, Cell)
  • "Allele-specific depletion of GNAQQ209L via siRNA or an rAAV2-shRNA vector induces selective toxicity in GNAQQ209L uveal melanoma cells" (2025, Molecular Therapy Oncology)

Frequent coauthors contributing to these works are:

  • Rachael L. Philips
  • Yuxin Wang
  • HyeonJoo Cheon
  • Yuka Kanno
  • Massimo Gadina

Darnell's research career has been recognized with several awards and honors, including the US President's National Medal of Science awarded in 2002 for seminal discoveries related to gene expression and signal transduction pathways. Additional distinctions include the E.B. Wilson Medal from the American Society for Cell Biology (1998), Fellowship in the Royal Society, United Kingdom (1996), Fellowship of the American Association for the Advancement of Science (AAAS) in 1991 and again in 1963, the Canada Gairdner International Award (1986), and Fellowship of the American Academy of Arts and Sciences (1973).

Best Publications

  • Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

    James E. Darnell;Ian M. Kerr;George Stark Stark

  • STATs and Gene Regulation

    Jr. James E. Darnell

  • STATs: transcriptional control and biological impact

    David E. Levy;J. E. Darnell

  • Stat3 as an Oncogene

    Jacqueline F Bromberg;Melissa H Wrzeszczynska;Geeta Devgan;Yanxiang Zhao

  • Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

    Zhong Zhong;Zilong Wen;James E. Darnell

  • Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation.

    Zilong Wen;Zhong Zhong;James E Darnell

  • The JAK-STAT pathway at twenty.

    George R. Stark;James E. Darnell

  • Transcription factors as targets for cancer therapy

    James E. Darnell

  • The role of STATs in transcriptional control and their impact on cellular function.

    Jacqueline Bromberg;James E Darnell

  • Leptin activation of Stat3 in the hypothalamus of wild–type and ob/ob mice but not db/db mice

    Christian Vaisse;Jeffrey L Halaas;Curt M. Horvath;James E. Darnell

  • Sedimentation characteristics of rapidly labelled RNA from HeLa cells

    Klaus Scherrer;J.E. Darnell

  • Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors

    Neil Stahl;Thomas J. Farruggella;Teri G. Boulton;Zhong Zhong

  • Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily.

    F M Sladek;W M Zhong;E Lai;J E Darnell

  • Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor.

    Chris Schindler;Ke Shuai;Vincent R. Prezioso;James E. Darnell

  • A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma

    Ke Shuai;George R. Stark;Ian M. Kerr;James E. Darnell

  • Activation of transcription by IFN-gamma: tyrosine phosphorylation of a 91-kD DNA binding protein

    Ke Shuai;Chris Schindler;Vincent R. Prezioso;James E. Darnell

  • Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions.

    Ke Shuai;Curt M. Horvath;Linda H.Tsai Huang;Sajjad A. Qureshi

  • A common nuclear signal transduction pathway activated by growth factor and cytokine receptors.

    Henry B. Sadowski;Ke Shuai;James E. Darnell;Michael Z. Gilman

  • Signal transduction and the control of gene expression.

    Ali H. Brivanlou;James E. Darnell

  • ErratumStat3 as an Oncogene

    Jacqueline F Bromberg;Melissa H Wrzeszczynska;Geeta Devgan;Yanxiang Zhao

Frequent Co-Authors

Zilong Wen
Zilong Wen Hong Kong University of Science and Technology
David E. Levy
David E. Levy New York University
Curt M. Horvath
Curt M. Horvath Northwestern University
John Kuriyan
John Kuriyan Vanderbilt University
Xin Yuan Fu
Xin Yuan Fu National University of Singapore
Ke Shuai
Ke Shuai University of California, Los Angeles
Frances M. Sladek
Frances M. Sladek University of California, Riverside
Thomas Decker
Thomas Decker University of Vienna
Ronald M. Evans
Ronald M. Evans Salk Institute for Biological Studies
Nigel W. Fraser
Nigel W. Fraser University of Pennsylvania

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