Xin Yuan Fu

Overview

Best Publications

• In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration

  Keiichiro Suzuki;Yuji Tsunekawa;Reyna Hernández-Benítez;Reyna Hernández-Benítez;Jun Wu;Jun Wu

  1266
  Citations

• Function of Mitochondrial Stat3 in Cellular Respiration

  Joanna Wegrzyn;Ramesh Potla;Yong Joon Chwae;Naresh B.V. Sepuri

  1160
  Citations

• Subcortical brain volume differences in participants with attention deficit hyperactivity disorder in children and adults: a cross-sectional mega-analysis

  Martine Hoogman;Janita Bralten;Derrek P. Hibar;Maarten Mennes

  1012
  Citations

• Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1

  Yue E. Chin;Motoo Kitagawa;Wu Chou S. Su;Zhi Hao You

  1009
  Citations

• Proteins of transcription factor ISGF-3: one gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon alpha.

  Chris Schindler;Xin Yuan Fu;Teresa Improta;Ruedi Aebersold

  861
  Citations

• The proteins of ISGF-3, the interferon alpha-induced transcriptional activator, define a gene family involved in signal transduction.

  Xin Yuan Fu;Chris Schindler;Teresa Improta;Ruedi Aebersold

  740
  Citations

• Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis.

  Y E Chin;M Kitagawa;K Kuida;R A Flavell

  679
  Citations

• ISGF3, the transcriptional activator induced by interferon alpha, consists of multiple interacting polypeptide chains.

  Xin Yuan Fu;Daniel S. Kessler;Susan A. Veals;David E. Levy

  622
  Citations

• A transcription factor with SH2 and SH3 domains is directly activated by an interferon α-induced cytoplasmic protein tyrosine kinase(s)

  Xin Yuan Fu

  512
  Citations

• Subunit of an alpha-interferon-responsive transcription factor is related to interferon regulatory factor and Myb families of DNA-binding proteins.

  Susan A. Veals;Chris Schindler;Debra Leonard;Xin Yuan Fu

  507
  Citations

• STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity.

  Thomas Welte;Samuel S.M. Zhang;Tian Wang;Zhiyuan Zhang

  483
  Citations

• Interferon-alpha regulates nuclear translocation and DNA-binding affinity of ISGF3, a multimeric transcriptional activator.

  Daniel S. Kessler;Susan A. Veals;Xin Yuan Fu;David E. Levy

  430
  Citations

• Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation

  Qian Gao;Michael J. Wolfgang;Susanne Neschen;Katsutaro Morino

  428
  Citations

• IFN-γ Induces Cell Growth Inhibition by Fas-mediated Apoptosis: Requirement of STAT1 Protein for Up-Regulation of Fas and FasL Expression

  Xiulong Xu;Xin-Yuan Fu;Janet Plate;Anita S-F. Chong

  422
  Citations

• STAT3 Is Required for Flt3L-Dependent Dendritic Cell Differentiation

  Yasmina Laouar;Thomas Welte;Xin Yuan Fu;Richard A. Flavell

  416
  Citations

• Transcription factor p91 interacts with the epidermal growth factor receptor and mediates activation of the c-fos gene promoter

  Xin-Yuan Fu;Jiao-Jiao Zhang

  397
  Citations

• Cardiomyocyte-restricted knockout of STAT3 results in higher sensitivity to inflammation, cardiac fibrosis, and heart failure with advanced age

  Jörg J. Jacoby;April Kalinowski;Mu Gen Liu;Mu Gen Liu;Samuel S.M. Zhang

  395
  Citations

• Smad4 signalling in T cells is required for suppression of gastrointestinal cancer

  Byung Gyu Kim;Cuiling Li;Wenhui Qiao;Mizuko Mamura

  385
  Citations

• Activation of Stat1 by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism.

  Wu Chou S. Su;Motoo Kitagawa;Ninrong Xue;Bing Xie

  354
  Citations

• Carbon monoxide differentially modulates STAT1 and STAT3 and inhibits apoptosis via a phosphatidylinositol 3-kinase/Akt and p38 kinase-dependent STAT3 pathway during anoxia-reoxygenation injury.

  Xuchen Zhang;Peiying Shan;Jawed Alam;Xin-Yuan Fu

  272
  Citations