Andrew C. Larner

Overview

Best Publications

• Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein

  Chao Lan Yu;Debra J. Meyer;George S. Campbell;Andrew C. Larner

  1413
  Citations

• Function of Mitochondrial Stat3 in Cellular Respiration

  Joanna Wegrzyn;Ramesh Potla;Yong Joon Chwae;Naresh B.V. Sepuri

  1160
  Citations

• Mitochondrial STAT3 supports Ras-dependent oncogenic transformation.

  Daniel J. Gough;Alicia Corlett;Karni Schlessinger;Joanna Wegrzyn

  837
  Citations

• Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins

  Michael David;Emanuel Petricoin;Christopher Benjamin;Richard Pine

  675
  Citations

• Interleukin-10 Inhibits Expression of Both Interferon – and Interferon γ– Induced Genes by Suppressing Tyrosine Phosphorylation of STAT1

  Satoshi Ito;Parswa Ansari;Minoru Sakatsume;Harold Dickensheets

  597
  Citations

• Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes.

  Chris M. Bacon;Emanuel F. Petricoin;John R. Ortaldo;Robert C. Rees

  579
  Citations

• Differential regulation of the alpha/beta interferon-stimulated Jak/Stat pathway by the SH2 domain-containing tyrosine phosphatase SHPTP1.

  M David;H E Chen;S Goelz;A C Larner

  466
  Citations

• Tyrosine phosphorylation of DNA binding proteins by multiple cytokines

  Andrew C. Larner;Michael David;Gerald M. Feldman;Ken-Ichi Igarashi

  431
  Citations

• Interferon-gamma induces tyrosine phosphorylation of interferon-gamma receptor and regulated association of protein tyrosine kinases, Jak1 and Jak2, with its receptor.

  K. Igarashi;G. Garotta;L. Ozmen;A. Ziemiecki

  254
  Citations

• STAT Activation by Epidermal Growth Factor (EGF) and Amphiregulin REQUIREMENT FOR THE EGF RECEPTOR KINASE BUT NOT FOR TYROSINE PHOSPHORYLATION SITES OR JAK1

  Michael David;Lily Wong;Richard Flavell;Stewart A. Thompson

  234
  Citations

• Interferon-stimulated transcription: isolation of an inducible gene and identification of its regulatory region

  D Levy;A Larner;A Chaudhuri;L E Babiss

  228
  Citations

• The Import of the Transcription Factor STAT3 into Mitochondria Depends on GRIM-19, a Component of the Electron Transport Chain

  Prasad Tammineni;Chandrashekhar Anugula;Fareed Mohammed;Murari Anjaneyulu

  226
  Citations

• Growth hormone induces a DNA binding factor related to the interferon-stimulated 91-kDa transcription factor

  Debra J. Meyer;George S. Campbell;Brent H. Cochran;Lawrence S. Argetsinger

  222
  Citations

• Control of lytic function by mitogen-activated protein kinase/extracellular regulatory kinase 2 (ERK2) in a human natural killer cell line: identification of perforin and granzyme B mobilization by functional ERK2.

  Sheng Wei;Ana M. Gamero;Jin Hong Liu;Angela A. Daulton

  215
  Citations

• Prolactin recruits STAT1, STAT3 and STAT5 independent of conserved receptor tyrosines TYR402, TYR479, TYR515 and TYR580

  Luis DaSilva;Hallgeir Rui;Rebecca A. Erwin;O.M. Zack Howard

  214
  Citations

• The Jak Kinases Differentially Associate with the α and β (Accessory Factor) Chains of the Interferon γ Receptor to Form a Functional Receptor Unit Capable of Activating STAT Transcription Factors

  Minoru Sakatsume;Ken-ichi Igarashi;Karen D. Winestock;Gianni Garotta

  204
  Citations

• Phosphorylation Events Modulate the Ability of Interferon Consensus Sequence Binding Protein to Interact with Interferon Regulatory Factors and to Bind DNA

  Rakefet Sharf;David Meraro;Aviva Azriel;Angela M. Thornton

  200
  Citations

• Toward a new STATe: The role of STATs in mitochondrial function

  Jeremy A. Meier;Andrew C. Larner

  199
  Citations

• Mitochondrial-targeted Signal Transducer and Activator of Transcription 3 (STAT3) Protects against Ischemia-induced Changes in the Electron Transport Chain and the Generation of Reactive Oxygen Species

  Karol Szczepanek;Qun Chen;Marta Derecka;Marta Derecka;Fadi N. Salloum

  197
  Citations

• Antiproliferative action of interferon-alpha requires components of T-cell-receptor signalling.

  Emanuel F. Petricoin;Satoshi Ito;Brandi L. Williams;Susette Audet

  197
  Citations