Andrew C. Larner mainly focuses on Tyrosine phosphorylation, Molecular biology, Phosphorylation, Signal transduction and Cell biology. His Tyrosine phosphorylation research includes themes of ROR1, Tyrosine kinase and Cancer research. The Molecular biology study combines topics in areas such as STAT2, STAT3 and SH2 domain.
His study on Phosphorylation is mostly dedicated to connecting different topics, such as Transcription factor. Andrew C. Larner works in the field of Signal transduction, focusing on STAT protein in particular. His studies deal with areas such as Receptor tyrosine kinase and JAK-STAT signaling pathway as well as Protein tyrosine phosphatase.
Andrew C. Larner focuses on Cell biology, Molecular biology, Tyrosine phosphorylation, Signal transduction and Transcription factor. In his study, T-cell receptor, Programmed cell death and Apoptosis is strongly linked to Cytokine, which falls under the umbrella field of Cell biology. RNA is closely connected to Transcription in his research, which is encompassed under the umbrella topic of Molecular biology.
His Tyrosine phosphorylation research integrates issues from Tyrosine kinase, Cancer research and Receptor tyrosine kinase. His Signal transduction study results in a more complete grasp of Biochemistry. Andrew C. Larner works mostly in the field of Transcription factor, limiting it down to concerns involving Interferon gamma and, occasionally, Phosphatase.
His primary areas of investigation include Cell biology, Mitochondrion, STAT3, Transcription factor and Electron Transport Complex I. His study in the field of Wnt signaling pathway also crosses realms of Mitophagy. The STAT3 study which covers Molecular biology that intersects with Serine.
His Transcription factor research incorporates themes from Adipose tissue, Endocrinology, Internal medicine, Signal transduction and STAT protein. To a larger extent, Andrew C. Larner studies Biochemistry with the aim of understanding Signal transduction. His research in Oxidative stress intersects with topics in Mitochondrial apoptosis-induced channel and Tyrosine phosphorylation.
His scientific interests lie mostly in Mitochondrion, Cell biology, STAT3, Electron Transport Complex I and Transcription factor. His study looks at the intersection of Mitochondrion and topics like STAT2 with STAT5, STAT6 and STAT1. His Cell biology study typically links adjacent topics like Molecular biology.
Andrew C. Larner interconnects Cytoprotection, Oxidative phosphorylation and Electron transport chain in the investigation of issues within ATP–ADP translocase. The various areas that Andrew C. Larner examines in his Mitochondrial transport study include Chaperone and Inner mitochondrial membrane. His STAT protein study contributes to a more complete understanding of Phosphorylation.
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Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein
Chao Lan Yu;Debra J. Meyer;George S. Campbell;Andrew C. Larner.
Function of Mitochondrial Stat3 in Cellular Respiration
Joanna Wegrzyn;Ramesh Potla;Yong Joon Chwae;Naresh B.V. Sepuri.
Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins
Michael David;Emanuel Petricoin;Christopher Benjamin;Richard Pine.
Mitochondrial STAT3 supports Ras-dependent oncogenic transformation.
Daniel J. Gough;Alicia Corlett;Karni Schlessinger;Joanna Wegrzyn.
Interleukin-10 Inhibits Expression of Both Interferon – and Interferon γ– Induced Genes by Suppressing Tyrosine Phosphorylation of STAT1
Satoshi Ito;Parswa Ansari;Minoru Sakatsume;Harold Dickensheets.
Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytes.
Chris M. Bacon;Emanuel F. Petricoin;John R. Ortaldo;Robert C. Rees.
Proceedings of the National Academy of Sciences of the United States of America (1995)
Differential regulation of the alpha/beta interferon-stimulated Jak/Stat pathway by the SH2 domain-containing tyrosine phosphatase SHPTP1.
M David;H E Chen;S Goelz;A C Larner.
Molecular and Cellular Biology (1995)
Tyrosine phosphorylation of DNA binding proteins by multiple cytokines
Andrew C. Larner;Michael David;Gerald M. Feldman;Ken-Ichi Igarashi.
Interferon-gamma induces tyrosine phosphorylation of interferon-gamma receptor and regulated association of protein tyrosine kinases, Jak1 and Jak2, with its receptor.
K. Igarashi;G. Garotta;L. Ozmen;A. Ziemiecki.
Journal of Biological Chemistry (1994)
STAT Activation by Epidermal Growth Factor (EGF) and Amphiregulin REQUIREMENT FOR THE EGF RECEPTOR KINASE BUT NOT FOR TYROSINE PHOSPHORYLATION SITES OR JAK1
Michael David;Lily Wong;Richard Flavell;Stewart A. Thompson.
Journal of Biological Chemistry (1996)
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