World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
65
Citations
10520
World Ranking
2557
National Ranking
1031

Research.com Recognitions

  • 2009 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1985 - Member of the National Academy of Medicine (NAM)

Overview

Joseph W. St. Geme is affiliated with the Children's Hospital of Philadelphia in the United States. Their research spans multiple disciplines within medicine and biochemistry, genetics, and molecular biology, with a particular focus on pediatric and infectious disease topics.

The scientist's scholarly contributions include a range of publications addressing pediatric subspecialties, infectious diseases, and bacterial pathogenesis. Recent papers published by Joseph W. St. Geme include:

  • Raising the Bar: The Need for Increased Financial Support to Sustain and Expand the Community of Pediatric Subspecialists (2023, The Journal of Pediatrics)
  • Leading from the Middle: Benefits of a Physician Leadership Program (2020, The Journal of Pediatrics)
  • Kingella negevensis shares multiple putative virulence factors with Kingella kingae (2020, PLoS ONE)
  • Immunization with HMW1 and HMW2 adhesins protects against colonization by heterologous strains of nontypeable Haemophilus influenzae (2021, Proceedings of the National Academy of Sciences)
  • The Kingella kingae PilC1 MIDAS Motif Is Essential for Type IV Pilus Adhesive Activity and Twitching Motility (2022, Infection and Immunity)

Their frequent coauthors include:

  • Eric A. Porsch
  • Vanessa L. Muñoz
  • Daniel P. Morreale
  • David Haslam
  • Nina R. Montoya

Joseph W. St. Geme's publications are commonly found in the following venues:

  • The Journal of Pediatrics
  • Pediatric Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • mBio
  • PLoS Pathogens

The main fields of study for Joseph W. St. Geme cover:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these broader areas, the scientist's subfields of focus include:

  • Public Health, Environmental and Occupational Health
  • Surgery
  • Epidemiology
  • General Health Professions
  • Molecular Biology

Their research topics further specify an emphasis on:

  • Streptococcal Infections and Treatments
  • Orthopedic Infections and Treatments
  • Infectious Diseases and Tuberculosis
  • Bacterial Identification and Susceptibility Testing
  • Diversity and Career in Medicine
  • Child and Adolescent Health
  • Innovations in Medical Education

Joseph W. St. Geme has been recognized with several honors, including Fellowship of the American Association for the Advancement of Science in 2009 and membership in the National Academy of Medicine since 1985.

Best Publications

  • Pilus and nonpilus bacterial adhesins: Assembly and function in cell recognition

    Scott J. Hultgren;Soman Abraham;Michael Caparon;Per Falk

  • Trimeric autotransporters : a distinct subfamily of autotransporter proteins

    Shane E. Cotter;Neeraj K. Surana;Joseph W. St. Geme

  • IDENTIFICATION OF A SECOND FAMILY OF HIGH-MOLECULAR-WEIGHT ADHESION PROTEINS EXPRESSED BY NON-TYPABLE HAEMOPHILUS INFLUENZAE

    Stephen J. Barenkamp;Joseph W. St. Geme

  • The Haemophilus influenzae HMW1 adhesin is glycosylated in a process that requires HMW1C and phosphoglucomutase, an enzyme involved in lipooligosaccharide biosynthesis.

    Susan Grass;Amy Z. Buscher;W. Edward Swords;Michael A. Apicella

  • Emergency Medical Services and the Pediatric Patient: Are the Needs Being Met?

    James S. Seidel;Mark Hornbein;Kathy Yoshiyama;Dorothy Kuznets

  • A HAEMOPHILUS INFLUENZAE IGA PROTEASE-LIKE PROTEIN PROMOTES INTIMATE INTERACTION WITH HUMAN EPITHELIAL CELLS

    St Geme Jw rd;de la Morena Ml;Falkow S

  • Kingella kingae: an emerging pathogen in young children.

    Pablo Yagupsky;Eric Porsch;Joseph W. St Geme

  • Structure of the outer membrane translocator domain of the Haemophilus influenzae Hia trimeric autotransporter.

    Guoyu Meng;Neeraj K Surana;Joseph W St Geme;Gabriel Waksman

  • Secretion of virulence determinants by the general secretory pathway in gram-negative pathogens: an evolving story.

    Christos Stathopoulos;David R Hendrixson;David G Thanassi;David G Thanassi;Scott J Hultgren

  • Prevalence and distribution of the hmw and hia genes and the HMW and Hia adhesins among genetically diverse strains of nontypeable Haemophilus influenzae.

    Joseph W. St. Geme;Vini V. Kumar;David Cutter;Stephen J. Barenkamp

  • Human milk lactoferrin inactivates two putative colonization factors expressed by Haemophilus influenzae

    Jiazhou Qiu;David R. Hendrixson;Edward N. Baker;Timothy F. Murphy

  • The Haemophilus influenzae Hap Serine Protease Promotes Adherence and Microcolony Formation, Potentiated by a Soluble Host Protein

    David R Hendrixson;Joseph W St. Geme

  • Hematogenous Osteomyelitis in Infants and Children: Imaging of a Changing Disease

    Diego Jaramillo;John P. Dormans;Jorge Delgado;Tal Laor

  • Identification and Characterization of an RTX Toxin in the Emerging Pathogen Kingella kingae

    Thomas E. Kehl-Fie;Thomas E. Kehl-Fie;Joseph W. St. Geme

  • Molecular determinants of the pathogenesis of disease due to non-typable Haemophilus influenzae.

    Venkatarama K. Rao;Graham P. Krasan;David R. Hendrixson;Suzanne Dawid

  • Molecular and cellular determinants of non-typeable Haemophilus influenzae adherence and invasion.

    Joseph W. St Geme

  • Structural determinants of processing and secretion of the Haemophilus influenzae Hap protein

    David R. Hendrixson;David R. Hendrixson;Maria L. De La Morena;Christos Stathopoulos;Joseph W. St Geme Iii

  • Impaired Cellular Resistance to Herpes-Simplex Virus in Wiskott-Aldrich Syndrome

    Joseph W. St. Geme;James T. Prince;Barbara A. Burke;Robert A. Good

  • The Haemophilus influenzae Hap autotransporter binds to fibronectin, laminin, and collagen IV.

    Doran L. Fink;Bruce A. Green;Joseph W. St. Geme

  • Loss of capsule expression by Haemophilus influenzae type b results in enhanced adherence to and invasion of human cells.

    J W St Geme rd;S Falkow

  • The Haemophilus influenzae Hia Adhesin Is an Autotransporter Protein That Remains Uncleaved at the C Terminus and Fully Cell Associated

    Joseph W. St. Geme;David Cutter

Frequent Co-Authors

Gabriel Waksman
Gabriel Waksman University College London
Pablo Yagupsky
Pablo Yagupsky Ben-Gurion University of the Negev
Andrew G. Plaut
Andrew G. Plaut Tufts Medical Center
Stanley Falkow
Stanley Falkow Stanford University
Scott J. Hultgren
Scott J. Hultgren Washington University in St. Louis
Timothy F. Murphy
Timothy F. Murphy University at Buffalo, State University of New York
Huilin Li
Huilin Li Van Andel Institute
Youngchang Kim
Youngchang Kim Argonne National Laboratory
Harold P. Erickson
Harold P. Erickson Duke University
Parastoo Azadi
Parastoo Azadi University of Georgia

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