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Françoise Jacob-Dubuisson

Françoise Jacob-Dubuisson

D-Index & Metrics

Biology and Biochemistry

D-Index
41
Citations
6474
World Ranking
19558
National Ranking
949

Overview

Françoise Jacob-Dubuisson is affiliated with the Institut Pasteur in France and has contributed extensively to the fields of biochemistry, genetics, and molecular biology. Their research encompasses a range of topics primarily focused on bacterial genetics, microbial natural products, and molecular mechanisms relevant to health and disease.

Their main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these fields, they specialize in subfields such as:

  • Molecular Biology
  • Genetics
  • Microbiology
  • Pharmacology
  • Nutrition and Dietetics

Jacob-Dubuisson's work addresses key topics related to bacterial systems and their interactions with hosts and environments. The main research topics they cover are:

  • Bacterial Genetics and Biotechnology
  • Bacterial Infections and Vaccines
  • Microbial Natural Products and Biosynthesis
  • Bacterial biofilms and quorum sensing
  • Trace Elements in Health
  • Escherichia coli research studies
  • RNA and protein synthesis mechanisms

They have published in several venues, demonstrating a consistent presence in well-regarded journals and repositories. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Zenodo (CERN European Organization for Nuclear Research)
  • Virulence
  • Proceedings of the National Academy of Sciences
  • mBio

Notable recent papers by Françoise Jacob-Dubuisson include:

  • "Pathogenicity and virulence of Bordetella pertussis and its adaptation to its strictly human host," 2021, published in Virulence
  • "Posttranscriptional Regulation by Copper with a New Upstream Open Reading Frame," 2022, published in mBio
  • "A widespread family of ribosomal peptide metallophores involved in bacterial adaptation to metal stress," 2024, published in Proceedings of the National Academy of Sciences
  • "Streamlined copper defenses make Bordetella pertussis reliant on custom-made operon," 2021, published in Communications Biology
  • "Structural Insight into the Role of the PAS Domain for Signal Transduction in Sensor Kinase BvgS," 2021, published in Journal of Bacteriology

Jacob-Dubuisson collaborates frequently with several researchers in their field, including:

  • Rudy Antoine
  • Alex Rivera-Millot
  • Giuseppe Sicoli
  • Laura Leprévost
  • Guy Lippens

Best Publications

  • Two-partner secretion in Gram-negative bacteria: a thrifty, specific pathway for large virulence proteins.

    Françoise Jacob‐Dubuisson;Camille Locht;Rudy Antoine

  • Structure of the membrane protein FhaC: a member of the Omp85-TpsB transporter superfamily.

    Bernard Clantin;Anne-Sophie Delattre;Prakash Rucktooa;Nathalie Saint

  • Outer-membrane PapC molecular usher discriminately recognizes periplasmic chaperone-pilus subunit complexes.

    Karen W. Dodson;Francoise Jacob-Dubuisson;Robert T. Striker;Scott J. Hultgren

  • Structural insights into the signalling mechanisms of two-component systems.

    Françoise Jacob-Dubuisson;Ariel Mechaly;Jean-Michel Betton;Rudy Antoine

  • The crystal structure of filamentous hemagglutinin secretion domain and its implications for the two-partner secretion pathway

    Bernard Clantin;Hélène Hodak;Eve Willery;Camille Locht

  • Protein secretion through autotransporter and two-partner pathways.

    Françoise Jacob-Dubuisson;Rachel Fernandez;Loic Coutte

  • Initiation of assembly and association of the structural elements of a bacterial pilus depend on two specialized tip proteins.

    F Jacob-Dubuisson;J Heuser;K Dodson;S Normark

  • Beta‐helix model for the filamentous haemagglutinin adhesin of Bordetella pertussis and related bacterial secretory proteins

    Andrey V. Kajava;Naiqian Cheng;Ryan Cleaver;Martin Kessel

  • PapD chaperone function in pilus biogenesis depends on oxidant and chaperone-like activities of DsbA

    Francoise Jacob-Dubuisson;Jerome Pinkner;Zheng Xu;Robert Striker

  • Subtilisin-like autotransporter serves as maturation protease in a bacterial secretion pathway

    Loic Coutte;Rudy Antoine;Hervé Drobecq;Camille Locht

  • Chaperone-assisted self-assembly of pili independent of cellular energy.

    F Jacob-Dubuisson;R Striker;S J Hultgren

  • Role of Adhesin Release for Mucosal Colonization by a Bacterial Pathogen

    Loïc Coutte;Sylvie Alonso;Nathalie Reveneau;Eve Willery

  • Novel topological features of FhaC, the outer membrane transporter involved in the secretion of the Bordetella pertussis filamentous hemagglutinin.

    Sandrine Guédin;Eve Willery;Jan Tommassen;Emmanuelle Fort

  • Bordetella pertussis, molecular pathogenesis under multiple aspects.

    Camille Locht;Rudy Antoine;Françoise Jacob-Dubuisson

  • Channel Formation by FhaC, the Outer Membrane Protein Involved in the Secretion of the Bordetella pertussis Filamentous Hemagglutinin

    Françoise Jacob-Dubuisson;Chahrazed El-Hamel;Nathalie Saint;Sandrine Guédin

  • Secretion signal of the filamentous haemagglutinin, a model two‐partner secretion substrate

    Hélène Hodak;Hélène Hodak;Bernard Clantin;Bernard Clantin;Eve Willery;Eve Willery;Vincent Villeret;Vincent Villeret

  • New Virulence-Activated and Virulence-Repressed Genes Identified by Systematic Gene Inactivation and Generation of Transcriptional Fusions in Bordetella pertussis

    Rudy Antoine;Sylvie Alonso;Dominique Raze;Loïc Coutte

  • Lack of functional complementation between Bordetella pertussis filamentous hemagglutinin and Proteus mirabilis HpmA hemolysin secretion machineries.

    Françoise Jacob-Dubuisson;Corinne Buisine;Eve Willery;Geneviève Renauld-Mongénie

  • N‐terminal characterization of the Bordetella pertussis filamentous haemagglutinin

    Corinne Lambert‐Buisine;Eve Willery;Camille Locht;Françoise Jacob‐Dubuisson

  • Evidence that a globular conformation is not compatible with FhaC‐mediated secretion of the Bordetella pertussis filamentous haemagglutinin

    Sandrine Guédin;Eve Willery;Camille Locht;Françoise Jacob‐Dubuisson

Frequent Co-Authors

Camille Locht
Camille Locht Institut Pasteur
Scott J. Hultgren
Scott J. Hultgren Washington University in St. Louis
Hervé Vezin
Hervé Vezin University of Lille
André Capron
André Capron Institut Pasteur
Sylvie Alonso
Sylvie Alonso National University of Singapore
Philippe Froguel
Philippe Froguel Imperial College London
Frank Sobott
Frank Sobott University of Leeds
Frits R. Mooi
Frits R. Mooi National Institute of Public Health and the Environment (RIVM)
David A. Relman
David A. Relman Stanford University
Ruiting Lan
Ruiting Lan University of New South Wales

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