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D-Index & Metrics

Molecular Biology

D-Index
64
Citations
12688
World Ranking
1757
National Ranking
881

Research.com Recognitions

  • 2003 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

David A. Low is affiliated with the University of California, Santa Barbara in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with particular attention to subfields such as endocrinology, genetics, infectious diseases, molecular medicine, and molecular biology.

Low's work encompasses numerous topics related to bacterial research and biotechnology. Key areas covered include Vibrio bacteria research studies, bacterial genetics and biotechnology, Escherichia coli research studies, antibiotic resistance in bacteria, bacterial biofilms and quorum sensing, Clostridium difficile and Clostridium perfringens research, and bacteriophages and microbial interactions.

Frequent collaborators in their research include Christopher S. Hayes, Zachary C. Ruhe, Fernando Garza-Sánchez, Dinh Q. Nhan, and Steven J. Jensen.

Some of Low's recent publications are:

  • Polymorphic Toxins and Their Immunity Proteins: Diversity, Evolution, and Mechanisms of Delivery (2020), Annual Review of Microbiology
  • Assessment of a Smartphone-Based Loop-Mediated Isothermal Amplification Assay for Detection of SARS-CoV-2 and Influenza Viruses (2022), JAMA Network Open
  • The β-encapsulation cage of rearrangement hotspot (Rhs) effectors is required for type VI secretion (2020), Proceedings of the National Academy of Sciences
  • A broad-spectrum synthetic antibiotic that does not evoke bacterial resistance (2023), EBioMedicine
  • Genetic Evidence for SecY Translocon-Mediated Import of Two Contact-Dependent Growth Inhibition (CDI) Toxins (2021), mBio

They have published frequently in venues such as Proceedings of the National Academy of Sciences, mBio, Nature Communications, bioRxiv (Cold Spring Harbor Laboratory), and Annual Review of Microbiology.

In recognition of their contributions, Low was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2003.

Best Publications

  • Epigenetic Gene Regulation in the Bacterial World

    Josep Casadesús;David Low

  • An essential role for DNA adenine methylation in bacterial virulence.

    Douglas M. Heithoff;Robert L. Sinsheimer;David A. Low;Michael J. Mahan

  • Protease-nexin: a cellular component that links thrombin and plasminogen activator and mediates their binding to cells.

    Joffre B. Baker;David A. Low;Robert L. Simmer;Dennis D. Cunningham

  • Contact-dependent inhibition of growth in Escherichia coli.

    Stephanie K. Aoki;Rupinderjit Pamma;Aaron D. Hernday;Jessica E. Bickham

  • Rhs proteins from diverse bacteria mediate intercellular competition

    Sanna Koskiniemi;James G. Lamoureux;Kiel C. Nikolakakis;Claire t'Kint de Roodenbeke

  • Roles of DNA Adenine Methylation in Regulating Bacterial Gene Expression and Virulence

    David A. Low;Nathan J. Weyand;Michael J. Mahan

  • A widespread family of polymorphic contact-dependent toxin delivery systems in bacteria

    Stephanie K. Aoki;Elie J. Diner;Claire T.Kint De Roodenbeke;Brandt R. Burgess

  • Bacterial contact-dependent delivery systems.

    Christopher S Hayes;Stephanie K Aoki;David A Low

  • The Role of Secretion Systems and Small Molecules in Soft-Rot Enterobacteriaceae Pathogenicity

    Amy Charkowski;Carlos Blanco;Guy Condemine;Dominique Expert

  • Programmed Heterogeneity: Epigenetic Mechanisms in Bacteria

    Josep Casadesús;David A. Low

  • Regulation of pap pilin phase variation by a mechanism involving differential dam methylation states.

    L. B. Blyn;B. A. Braaten;D. A. Low

  • Methylation patterns in pap regulatory DNA control pyelonephritis-associated pili phase variation in E. coli

    B.A. Braaten;X. Nou;L.S. Kaltenbach;D.A. Low

  • Released protease-nexin regulates cellular binding, internalization, and degradation of serine proteases.

    David A. Low;Joffre B. Baker;William C. Koonce;Dennis D. Cunningham

  • Identification of Functional Toxin/Immunity Genes Linked to Contact-Dependent Growth Inhibition (CDI) and Rearrangement Hotspot (Rhs) Systems

    Stephen J. Poole;Elie J. Diner;Stephanie K. Aoki;Bruce A. Braaten

  • Contact-dependent growth inhibition requires the essential outer membrane protein BamA (YaeT) as the receptor and the inner membrane transport protein AcrB

    Stephanie K. Aoki;Juliana C. Malinverni;Kyle Jacoby;Benjamin Thomas

  • DNA adenine methylase is essential for viability and plays a role in the pathogenesis of Yersinia pseudotuberculosis and Vibrio cholerae.

    Steven M. Julio;Douglas M. Heithoff;Daniele Provenzano;Karl E. Klose

  • Genetically distinct pathways guide effector export through the type VI secretion system

    John C. Whitney;Christina M. Beck;Young Ah Goo;Alistair B. Russell

  • Bacterial contact-dependent growth inhibition.

    Zachary C. Ruhe;David A. Low;Christopher S. Hayes

  • Epigenetic phase variation of the pap operon in Escherichia coli

    Marjan W. van der Woude;Bruce A. Braaten;David A. Low

  • Gal-Gal binding and hemolysin phenotypes and genotypes associated with uropathogenic Escherichia coli.

    Peter O'Hanley;David Low;Irevis Romero;David Lark

Frequent Co-Authors

Dennis D. Cunningham
Dennis D. Cunningham University of California, Irvine
Lawrence B. Blyn
Lawrence B. Blyn Ionis Pharmaceuticals (United States)
David Cunningham
David Cunningham Royal Marsden NHS Foundation Trust
Andrzej Joachimiak
Andrzej Joachimiak Argonne National Laboratory
Stanley Falkow
Stanley Falkow Stanford University
Gary K. Schoolnik
Gary K. Schoolnik Stanford University
Sharon J. Peacock
Sharon J. Peacock University of Cambridge
Josep Casadesús
Josep Casadesús University of Seville
Paul Keim
Paul Keim Northern Arizona University
Elaine H. Zackai
Elaine H. Zackai Children's Hospital of Philadelphia

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