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Microbiology
USA
2026

D-Index & Metrics

Microbiology

D-Index
130
Citations
58440
World Ranking
77
National Ranking
37

Research.com Recognitions

  • 2026 - Research.com Microbiology in United States Leader Award
  • 2025 - Research.com Microbiology in United States Leader Award
  • 2020 - Fellow, National Academy of Inventors
  • 2017 - Member of the National Academy of Medicine (NAM)
  • 2011 - Member of the National Academy of Sciences
  • 2009 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Scott J. Hultgren is affiliated with Washington University in St. Louis in the United States. Their research primarily focuses on urinary tract infections (UTIs), microbial pathogenesis, and host-pathogen interactions. The scientist's work spans several fields of study, with Medicine and Biochemistry, Genetics and Molecular Biology being the main disciplines. Subfields include Epidemiology, Molecular Biology, Endocrinology, Surgery, and Rheumatology.

Key topics addressed in Scott J. Hultgren's research include:

  • Urinary Tract Infections Management
  • Escherichia coli research studies
  • Gut microbiota and health
  • Pelvic floor disorders treatments
  • Antibiotic Resistance in Bacteria
  • Antimicrobial Resistance in Staphylococcus
  • Urinary Bladder and Prostate Research

Scott J. Hultgren has contributed to several recent publications, among them:

  • "Urinary tract infections: microbial pathogenesis, host-pathogen interactions and new treatment strategies" (2020, Nature Reviews Microbiology)
  • "Longitudinal multi-omics analyses link gut microbiome dysbiosis with recurrent urinary tract infections in women" (2022, Nature Microbiology)
  • "StrainGE: a toolkit to track and characterize low-abundance strains in complex microbial communities" (2022, Genome Biology)
  • "Urinary tract infections: pathogenesis, host susceptibility and emerging therapeutics" (2024, Nature Reviews Microbiology)
  • "Microbial co-occurrences on catheters from long-term catheterized patients" (2024, Nature Communications)

The scientist frequently publishes in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Microbiology
  • Nature Communications
  • Proceedings of the National Academy of Sciences
  • Science Advances

Notable frequent co-authors include:

  • Karen Dodson
  • Jerome S. Pinkner
  • Chloe L. P. Obernuefemann
  • Andrew L. Kau
  • Ashlee M. Earl

Scott J. Hultgren's recognition within the scientific community includes election to several prestigious bodies and fellowships:

  • Fellow, National Academy of Inventors, 2020
  • Member of the National Academy of Medicine (NAM), 2017
  • Member of the National Academy of Sciences, 2011
  • Fellow of the American Association for the Advancement of Science (AAAS), 2009

Best Publications

  • Urinary tract infections: epidemiology, mechanisms of infection and treatment options

    Ana L Flores-Mireles;Jennifer N Walker;Michael G. Caparon;Scott J. Hultgren

  • Induction and Evasion of Host Defenses by Type 1-Piliated Uropathogenic Escherichia Coli

    M.A. Mulvey;Y.S. Lopez-Boado;C.L. Wilson;R. Roth

  • Role of Escherichia coli Curli Operons in Directing Amyloid Fiber Formation

    Matthew R. Chapman;Lloyd S. Robinson;Jerome S. Pinkner;Robyn Roth

  • Intracellular bacterial biofilm-like pods in urinary tract infections

    Gregory G. Anderson;Joseph J. Palermo;Joel D. Schilling;Robyn Roth

  • Regulation of Intestinal α-Defensin Activation by the Metalloproteinase Matrilysin in Innate Host Defense

    Carole L. Wilson;Andre J. Ouellette;Donald P. Satchell;Tokiyoshi Ayabe

  • Bacterial Biofilms: Development, Dispersal, and Therapeutic Strategies in the Dawn of the Postantibiotic Era

    Maria Kostakioti;Maria Hadjifrangiskou;Scott J. Hultgren

  • Establishment of a persistent Escherichia coli reservoir during the acute phase of a bladder infection.

    Matthew A. Mulvey;Joel D. Schilling;Scott J. Hultgren

  • The biology and future prospects of antivirulence therapies

    Lynette Cegelski;Garland R. Marshall;Gary R. Eldridge;Scott J. Hultgren

  • Type 1 pilus‐mediated bacterial invasion of bladder epithelial cells

    Juan J. Martinez;Matthew A. Mulvey;Joel D. Schilling;Jerome S. Pinkner

  • Differentiation and developmental pathways of uropathogenic Escherichia coli in urinary tract pathogenesis.

    Sheryl S. Justice;Chia Hung;Julie A. Theriot;Daniel A. Fletcher

  • X-ray Structure of the FimC-FimH Chaperone-Adhesin Complex from Uropathogenic Escherichia coli

    Devapriya Choudhury;Andrew Thompson;Vivian Stojanoff;Solomon Langermann

  • Identification of genes subject to positive selection in uropathogenic strains of Escherichia coli: A comparative genomics approach

    Swaine L. Chen;Chia Seui Hung;Jian Xu;Christopher S. Reigstad

  • Morphological plasticity as a bacterial survival strategy.

    Sheryl S. Justice;David A. Hunstad;Lynette Cegelski;Scott J. Hultgren

  • Bad bugs and beleaguered bladders: interplay between uropathogenic Escherichia coli and innate host defenses.

    Matthew A. Mulvey;Joel D. Schilling;Juan J. Martinez;Scott J. Hultgren

  • Detection of intracellular bacterial communities in human urinary tract infection.

    David A S Rosen;Thomas M. Hooton;Walter E. Stamm;Peter A. Humphrey

  • Prevention of mucosal Escherichia coli infection by FimH-adhesin-based systemic vaccination.

    Solomon Langermann;Solomon Langermann;Susan Palaszynski;Susan Palaszynski;Michelle Barnhart;Michelle Barnhart;Gale Auguste;Gale Auguste

  • Mechanisms of uropathogenic Escherichia coli persistence and eradication from the urinary tract.

    Indira U. Mysorekar;Scott J. Hultgren

  • Bacterial adhesins: common themes and variations in architecture and assembly.

    Gabriel E. Soto;Scott J. Hultgren

  • FimH adhesin of type 1 pili is assembled into a fibrillar tip structure in the Enterobacteriaceae.

    C H Jones;J S Pinkner;R Roth;J Heuser

  • Pilus and nonpilus bacterial adhesins: Assembly and function in cell recognition

    Scott J. Hultgren;Soman Abraham;Michael Caparon;Per Falk

Frequent Co-Authors

Jerome S. Pinkner
Jerome S. Pinkner Washington University in St. Louis
Gabriel Waksman
Gabriel Waksman University College London
Michael G. Caparon
Michael G. Caparon Washington University in St. Louis
Jan Kihlberg
Jan Kihlberg Uppsala University
Staffan Normark
Staffan Normark Karolinska Institute
John E. Heuser
John E. Heuser Washington University in St. Louis
Thomas M. Hooton
Thomas M. Hooton University of Miami
Jeffrey I. Gordon
Jeffrey I. Gordon Washington University in St. Louis
Carl Frieden
Carl Frieden Washington University in St. Louis

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