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Microbiology

D-Index
72
Citations
19166
World Ranking
1747
National Ranking
747

Research.com Recognitions

  • 2017 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Michael G. Caparon is affiliated with Washington University in St. Louis in the United States. Their research primarily focuses on the field of Medicine, with particular specialization in epidemiology, public health, environmental and occupational health, infectious diseases, rheumatology, and molecular biology.

The main topics of their work include:

  • Streptococcal Infections and Treatments
  • Antimicrobial Resistance in Staphylococcus
  • Urinary Tract Infections Management
  • Pelvic floor disorders treatments
  • Antibiotic Resistance in Bacteria
  • Advanced Chemical Sensor Technologies
  • Respiratory and Cough-Related Research

Michael G. Caparon has published in several notable venues, including:

  • Nature Communications (3 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (3 publications)
  • PLoS Pathogens (1 publication)
  • Science Advances (1 publication)
  • Proceedings of the National Academy of Sciences (1 publication)

Recent papers include:

  • Microbial co-occurrences on catheters from long-term catheterized patients, 2024, Nature Communications
  • Ring-fused 2-pyridones effective against multidrug-resistant Gram-positive pathogens and synergistic with standard-of-care antibiotics, 2022, Proceedings of the National Academy of Sciences
  • Central carbon flux controls growth/damage balance for Streptococcus pyogenes, 2023, PLoS Pathogens
  • Fibrinolytic-deficiencies predispose hosts to septicemia from a catheter-associated UTI, 2024, Nature Communications
  • Dihydrothiazolo ring-fused 2-pyridone antimicrobial compounds treat Streptococcus pyogenes skin and soft tissue infection, 2024, Science Advances

Frequent collaborators include:

  • Scott J. Hultgren
  • Taylor M. Nye
  • Chloe L. P. Obernuefemann
  • Jerome S. Pinkner
  • Ana L. Flores-Mireles

In 2017, Michael G. Caparon was recognized as a Fellow of the American Association for the Advancement of Science (AAAS).

Best Publications

  • Urinary tract infections: epidemiology, mechanisms of infection and treatment options

    Ana L Flores-Mireles;Jennifer N Walker;Michael G. Caparon;Scott J. Hultgren

  • Lactobacillus reuteri induces gut intraepithelial CD4+CD8αα+ T cells.

    Luisa Cervantes-Barragan;Jiani N. Chai;Ma Diarey Tianero;Blanda Di Luccia

  • Pilus and nonpilus bacterial adhesins: Assembly and function in cell recognition

    Scott J. Hultgren;Soman Abraham;Michael Caparon;Per Falk

  • Mry, a trans-acting positive regulator of the M protein gene of Streptococcus pyogenes with similarity to the receptor proteins of two-component regulatory systems.

    J Perez-Casal;M G Caparon;J R Scott

  • Protein F, a fibronectin-binding protein, is an adhesin of the group A streptococcus Streptococcus pyogenes.

    Emanuel Hanski;Michael Caparon

  • Streptococcus-Zebrafish Model of Bacterial Pathogenesis

    Melody N. Neely;John D. Pfeifer;Michael Caparon

  • Membrane cofactor protein (CD46) is a keratinocyte receptor for the M protein of the group A streptococcus.

    N Okada;M K Liszewski;J P Atkinson;M Caparon

  • Cytolysin-Mediated Translocation (CMT): A Functional Equivalent of Type III Secretion in Gram-Positive Bacteria

    John C Madden;Natividad Ruiz;Michael Caparon

  • A role for Trigger Factor and an Rgg-like regulator in the transcription, secretion and processing of the cysteine proteinase of Streptococcus pyogenes

    William R. Lyon;Carmela M. Gibson;Michael G. Caparon

  • Genetic manipulation of pathogenic streptococci.

    Michael G. Caparon;June R. Scott

  • Visualizing pneumococcal infections in the lungs of live mice using bioluminescent Streptococcus pneumoniae transformed with a novel gram-positive lux transposon.

    Kevin P. Francis;Jun Yu;Carolyn Bellinger-Kawahara;Danny Joh

  • Mutation of luxS affects growth and virulence factor expression in Streptococcus pyogenes

    William R. Lyon;John C. Madden;James C. Levin;Jeffrey L. Stein

  • Environmental regulation of virulence in group A streptococci: transcription of the gene encoding M protein is stimulated by carbon dioxide

    M G Caparon;R T Geist;J Perez-Casal;J R Scott

  • Expression of protein F, the fibronectin-binding protein of Streptococcus pyogenes JRS4, in heterologous streptococcal and enterococcal strains promotes their adherence to respiratory epithelial cells.

    E. Hanski;P. A. Horwitz;Michael Caparon

  • Identification of a gene that regulates expression of M protein, the major virulence determinant of group A streptococci

    Michael G. Caparon;June R. Scott

  • A tale of two pili: assembly and function of pili in bacteria

    Kimberly A. Kline;Karen W. Dodson;Michael G. Caparon;Scott J. Hultgren

  • Excision and insertion of the conjugative transposon Tn916 involves a novel recombination mechanism

    Michael G. Caparon;June R. Scott

  • Patterns of virulence gene expression differ between biofilm and tissue communities of Streptococcus pyogenes.

    Kyu Hong Cho;Michael G. Caparon

  • Role of M protein in adherence of group A streptococci.

    M G Caparon;D S Stephens;A Olsén;J R Scott

  • A Microdomain for Protein Secretion in Gram-Positive Bacteria

    Jason Rosch;Michael Caparon

Frequent Co-Authors

Scott J. Hultgren
Scott J. Hultgren Washington University in St. Louis
Jerome S. Pinkner
Jerome S. Pinkner Washington University in St. Louis
June R. Scott
June R. Scott Emory University
Birgitta Henriques-Normark
Birgitta Henriques-Normark Karolinska Institute
Staffan Normark
Staffan Normark Karolinska Institute
Victor Nizet
Victor Nizet University of California, San Diego
Natividad Ruiz
Natividad Ruiz The Ohio State University
Tom Ellenberger
Tom Ellenberger Washington University in St. Louis
Marco Colonna
Marco Colonna Washington University in St. Louis
Lars Björck
Lars Björck Lund University

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