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Immunology

D-Index
64
Citations
12260
World Ranking
2963
National Ranking
1393

Overview

James B. Dale is affiliated with the University of Tennessee Health Science Center in the United States. Their research primarily focuses on medicine, with significant contributions to public health, environmental and occupational health, infectious diseases, epidemiology, clinical biochemistry, and molecular biology.

The scientist's main research topics include streptococcal infections and treatments, antimicrobial resistance in Staphylococcus, neonatal and maternal infections, otolaryngology and infectious diseases, infective endocarditis diagnosis and management, bacterial identification and susceptibility testing, and immune response and inflammation.

Recent publications by James B. Dale cover a range of topics within infectious diseases and public health:

  • Update on group A streptococcal vaccine development (2020), published in Current Opinion in Infectious Diseases
  • A controlled human infection model of Streptococcus pyogenes pharyngitis (CHIVAS-M75): an observational, dose-finding study (2021), published in The Lancet Microbe
  • The American Heart Association's Call to Action for Reducing the Global Burden of Rheumatic Heart Disease: A Policy Statement From the American Heart Association (2020), published in Circulation
  • Prevalence of group A β-hemolytic streptococcal throat carriage and prospective pilot surveillance of streptococcal sore throat in Ugandan school children (2020), published in International Journal of Infectious Diseases
  • Systematic Review and Meta-analysis of the Prevalence of Group A Streptococcal emm Clusters in Africa To Inform Vaccine Development (2020), published in mSphere

Frequently collaborating with James B. Dale are Mark E. Engel, Babu Muhamed, Kélin Engel, Andrea Beaton, and Michelle P. Aranha.

Their research has been published predominantly in the following venues:

  • Vaccine
  • Circulation
  • mSphere
  • Current Opinion in Infectious Diseases
  • The Lancet Microbe

Best Publications

  • Blocking Neuronal Signaling to Immune Cells Treats Streptococcal Invasive Infection

    Felipe A. Pinho-Ribeiro;Buket Baddal;Rianne Haarsma;Maghnus O’Seaghdha

  • Safety and Immunogenicity of 26-Valent Group A Streptococcus Vaccine in Healthy Adult Volunteers

    Shelly A. McNeil;Scott A. Halperin;Joanne M. Langley;Bruce Smith

  • New 30-valent M protein-based vaccine evokes cross-opsonic antibodies against non-vaccine serotypes of group A streptococci.

    James B. Dale;Thomas A. Penfound;Thomas A. Penfound;Edna Y. Chiang;Edna Y. Chiang;William J. Walton

  • A systematic and functional classification of Streptococcus pyogenes that serves as a new tool for molecular typing and vaccine development

    Martina L Sanderson-Smith;David M P De Oliveira;Julien Guglielmini;David J McMillan

  • Immunogenicity of a 26-valent group A streptococcal vaccine

    Mary C. Hu;Michael A. Walls;Steven D. Stroop;Mark A. Reddish

  • Epitopes of streptococcal M proteins shared with cardiac myosin.

    James B. Dale;Edwin H. Beachey

  • Epitopes of streptococcal M proteins that evoke antibodies that cross-react with human brain.

    M S Bronze;J B Dale

  • Hyaluronate capsule and surface M protein in resistance to opsonization of group A streptococci

    J B Dale;R G Washburn;M B Marques;M R Wessels

  • Cloning, sequencing, and expression of a fibronectin/fibrinogen-binding protein from group A streptococci.

    H. S. Courtney;Yi Li;J. B. Dale;D. L. Hasty

  • Type-specific protective immunity evoked by synthetic peptide of Streptococcus pyogenes M protein

    Edwin H. Beachey;Jerome M. Seyer;James B. Dale;W. Andrew Simpson

  • Prevalence of Rheumatic Heart Disease in Children and Young Adults in Nicaragua

    John A. Paar;Nubia M. Berrios;John D. Rose;Mercedes Cáceres

  • Molecular mechanisms of adhesion, colonization, and invasion of group A streptococci.

    Harry S Courtney;David L Hasty;James B Dale

  • Streptococcal C5a peptidase is a highly specific endopeptidase.

    P P Cleary;U Prahbu;J B Dale;D E Wexler

  • Human and murine antibodies cross-reactive with streptococcal M protein and myosin recognize the sequence GLN-LYS-SER-LYS-GLN in M protein.

    M W Cunningham;J M McCormack;P G Fenderson;M K Ho

  • Multiple, heart-cross-reactive epitopes of streptococcal M proteins.

    James B. Dale;Edwin H. Beachey

  • Safety and immunogenicity of a recombinant multivalent Group A streptococcal Vaccine in healthy adults: Phase 1 trial

    Karen L. Kotloff;Mary Corretti;Mary Corretti;Kathleen Palmer;James D. Campbell

  • Multivalent group A streptococcal vaccine designed to optimize the immunogenicity of six tandem M protein fragments

    James B Dale

  • SERUM OPACITY FACTOR IS A MAJOR FIBRONECTIN-BINDING PROTEIN AND A VIRULENCE DETERMINANT OF M TYPE 2 STREPTOCOCCUS PYOGENES

    Harry S. Courtney;David L. Hasty;David L. Hasty;Yi Li;Herbert C. Chiang

  • Group A Streptococcal Pharyngitis Serotype Surveillance in North America, 2000–2002

    Stanford T. Shulman;Robert R. Tanz;William Kabat;Kathleen Kabat

  • Temporal Changes in Streptococcal M Protein Types and the Near-Disappearance of Acute Rheumatic Fever in the United States

    Stanford T. Shulman;Gene Stollerman;Bernard Beall;James B. Dale

  • Protective antigenic determinant of streptococcal M protein shared with sarcolemmal membrane protein of human heart.

    James Dale;Edwin H. Beachey

Frequent Co-Authors

David L. Hasty
David L. Hasty University of Tennessee Health Science Center
Edwin H. Beachey
Edwin H. Beachey University of Tennessee Health Science Center
Stanford T. Shulman
Stanford T. Shulman Northwestern University
Bernard Beall
Bernard Beall Centers for Disease Control and Prevention
Jonathan R. Carapetis
Jonathan R. Carapetis Telethon Kids Institute
Jerome M. Seyer
Jerome M. Seyer University of Tennessee Health Science Center
P. Patrick Cleary
P. Patrick Cleary University of Minnesota
Michael F. Good
Michael F. Good Griffith University
Shelly A. McNeil
Shelly A. McNeil Dalhousie University
Itzhak Ofek
Itzhak Ofek Tel Aviv University

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