World's Best Scientists 2026 revealed!
Alexander Tarakhovsky

Alexander Tarakhovsky

D-Index & Metrics

Biology and Biochemistry

D-Index
66
Citations
23998
World Ranking
8470
National Ranking
3809

Overview

Alexander Tarakhovsky is affiliated with Rockefeller University in the United States and focuses their research primarily within the fields of Biochemistry, Genetics, and Molecular Biology. Their work spans several subfields including Molecular Biology, Immunology, Electrical and Electronic Engineering, Oncology, and Public Health, Environmental and Occupational Health.

The scientist's research topics cover a variety of areas with a strong emphasis on interferon and immune responses, genomics and chromatin dynamics, epigenetics and DNA methylation, RNA research and splicing, polyomavirus and related diseases, as well as aspects of full-duplex wireless communications and energy harvesting in wireless networks.

Frequent venues for their publications include bioRxiv (Cold Spring Harbor Laboratory) where they have published four papers, Frontiers in Immunology, FEBS Letters, Nature, and Genes & Development.

Notable recent papers include:

  • The catalytic domain of the histone methyltransferase NSD2/MMSET is required for the generation of B1 cells in mice, 2020, FEBS Letters
  • Control of enhancer and promoter activation in the type I interferon response by the histone demethylase Kdm4d/JMJD2d, 2023, Frontiers in Immunology
  • A histone-like motif in yellow fever virus contributes to viral replication, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Chromatin mimicry by human JC virus, 2024, bioRxiv (Cold Spring Harbor Laboratory)
  • Control of enhancer activation in the type I interferon response by the histone demethylase Kdm4d / JMJD2d, 2023, bioRxiv (Cold Spring Harbor Laboratory)

Alexander Tarakhovsky collaborates frequently with a group of co-authors including Rab K. Prinjha, Rohit Chandwani, Terry Fang, Scott Dewell, and Uwe Schaefer.

Best Publications

  • Suppression of inflammation by a synthetic histone mimic

    Edwige Nicodeme;Kate L. Jeffrey;Uwe Schaefer;Soren Beinke

  • Blimp1 is a critical determinant of the germ cell lineage in mice

    Yasuhide Ohinata;Bernhard Payer;Dónal O'Carroll;Katia Ancelin

  • Essential Role of the Histone Methyltransferase G9a in Cocaine-induced Plasticity

    Ian Maze;Herbert E. Iii. Covington;David M. Dietz;Quincey LaPlant;Quincey LaPlant

  • Maternal microRNAs are essential for mouse zygotic development

    Fuchou Tang;Masahiro Kaneda;Dónal O’Carroll;Petra Hajkova

  • Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement

    I-hsin Su;Ashwin Basavaraj;Andrew N. Krutchinsky;Oliver Hobert

  • Ezh2 Orchestrates Gene Expression for the Stepwise Differentiation of Tissue-Specific Stem Cells

    Elena Ezhkova;H. Amalia Pasolli;Joel S. Parker;Nicole Stokes

  • Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs

    Rui Yi;Dónal O'Carroll;Hilda A Pasolli;Zhihong Zhang

  • Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases.

    Masahiro Kawabuchi;Yoshinori Satomi;Toshifumi Takao;Yasutsugu Shimonishi

  • Immunodeficiency in Protein Kinase Cβ-Deficient Mice

    Michael Leitges;Christian Schmedt;Rodolphe Guinamard;Jean Davoust

  • A role for CD5 in TCR-mediated signal transduction and thymocyte selection

    Alexander Tarakhovsky;Steven B. Kanner;Joachim Hombach;Jeffrey A. Ledbetter

  • MicroRNA biogenesis is required for mouse primordial germ cell development and spermatogenesis.

    Katsuhiko Hayashi;Susana M. Chuva de Sousa Lopes;Masahiro Kaneda;Fuchou Tang

  • Blimp1 Defines a Progenitor Population that Governs Cellular Input to the Sebaceous Gland

    Valerie Horsley;Dónal O'Carroll;Reuben Tooze;Yasuhide Ohinata

  • Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav

    A. Tarakhovsky;M. Turner;S. Schaal;P. J. Mee

  • Dicer-dependent microRNA pathway safeguards regulatory T cell function.

    Adrian Liston;Li-Fan Lu;Donal O'Carroll;Alexander Tarakhovsky

  • Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex

    João D. Pereira;Stephen N. Sansom;James Smith;Marc-Werner Dobenecker

  • Negative regulation of Toll-like receptor 4 signaling by the Toll-like receptor homolog RP105

    Senad Divanovic;Aurelien Trompette;Sowsan F Atabani;Rajat Madan

  • Abnormal development of secondary lymphoid tissues in lymphotoxin beta-deficient mice.

    Marat B. Alimzhanov;Dmitry V. Kuprash;Marie H. Kosco-Vilbois;Arne Luz

  • A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway

    Dónal O’Carroll;Ingrid Mecklenbrauker;Partha Pratim Das;Angela Santana

  • The Toll-like Receptor Protein Rp105 Regulates Lipopolysaccharide Signaling in B Cells

    Hirotaka Ogata;I-hsin Su;Kensuke Miyake;Yoshinori Nagai

  • Polycomb Group Protein Ezh2 Controls Actin Polymerization and Cell Signaling

    I-hsin Su;Marc-Werner Dobenecker;Ephraim Dickinson;Matthew Oser

Frequent Co-Authors

Rab K. Prinjha
Rab K. Prinjha GlaxoSmithKline (United Kingdom)
Dónal O'Carroll
Dónal O'Carroll University of Edinburgh
Michel C. Nussenzweig
Michel C. Nussenzweig Rockefeller University
Vyacheslav Yurchenko
Vyacheslav Yurchenko University of Ostrava
Benjamin A. Garcia
Benjamin A. Garcia Washington University in St. Louis
M. Azim Surani
M. Azim Surani University of Cambridge
Klaus Rajewsky
Klaus Rajewsky Max Delbrück Center for Molecular Medicine
Michael Leitges
Michael Leitges University of Oslo
Elaine Fuchs
Elaine Fuchs Rockefeller University
Sheila C. Barton
Sheila C. Barton University of Cambridge

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