Dónal O'Carroll mainly investigates Genetics, Histone methyltransferase, Histone code, Histone H2A and EZH2. His study on microRNA, Embryonic stem cell and Germ cell is often connected to Epiblast as part of broader study in Genetics. Dónal O'Carroll combines subjects such as Cellular differentiation, Piwi-interacting RNA, Dicer and Cell biology with his study of microRNA.
His Histone methyltransferase research includes elements of Enhancer, Gene targeting, Histone deacetylase complex and SUZ12. His research investigates the connection with Histone H2A and areas like Histone H3 which intersect with concerns in Histone H1. His research in EZH2 intersects with topics in Epigenetics of physical exercise, Homeotic selector gene and Heterochromatin, Constitutive heterochromatin, Heterochromatin protein 1.
His primary scientific interests are in Cell biology, Genetics, microRNA, Gene silencing and Gene. His Cell biology research includes themes of Molecular biology, Transcriptome, Dicer and Germline. His Genetics study is mostly concerned with Histone methyltransferase, EZH2, Somatic cell, Embryonic stem cell and Messenger RNA.
His studies in Histone methyltransferase integrate themes in fields like Heterochromatin and Histone H3. He has included themes like DNA microarray, Gene expression, Gene expression profiling, Cellular differentiation and Inflammation in his microRNA study. His Gene silencing research is multidisciplinary, incorporating perspectives in DNA methylation, Reprogramming, Argonaute, Regulation of gene expression and Piwi-interacting RNA.
His main research concerns Cell biology, RNA, Piwi-interacting RNA, Gene and Transcriptome. His study in Cell biology is interdisciplinary in nature, drawing from both DNA methylation, Somatic cell, Germline, microRNA and Dicer. His Somatic cell study which covers Embryonic stem cell that intersects with Gene expression.
His study looks at the relationship between microRNA and fields such as Inflammation, as well as how they intersect with chemical problems. His Piwi-interacting RNA research is multidisciplinary, incorporating elements of Regulation of gene expression, Gene silencing and Spermatogenesis. His Messenger RNA research is classified as research in Genetics.
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Regulation of chromatin structure by site-specific histone H3 methyltransferases
S Rea;F Eisenhaber;D O'Carroll;B D Strahl.
Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins.
Monika Lachner;Dónal O'Carroll;Stephen Rea;Karl Mechtler.
Loss of the Suv39h Histone Methyltransferases Impairs Mammalian Heterochromatin and Genome Stability
Antoine H.F.M. Peters;Dónal O'Carroll;Harry Scherthan;Karl Mechtler.
Rb targets histone H3 methylation and HP1 to promoters
Soren J. Nielsen;Robert Schneider;Uta-Maria Bauer;Andrew J. Bannister.
Blimp1 is a critical determinant of the germ cell lineage in mice
Yasuhide Ohinata;Bernhard Payer;Dónal O'Carroll;Katia Ancelin.
The polycomb-group gene Ezh2 is required for early mouse development.
O'Carroll D;Erhardt S;Pagani M;Barton Sc.
Molecular and Cellular Biology (2001)
Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression
Gerda Lagger;Dónal O'Carroll;Martina Rembold;Harald Khier.
The EMBO Journal (2002)
Maternal microRNAs are essential for mouse zygotic development
Fuchou Tang;Masahiro Kaneda;Dónal O’Carroll;Petra Hajkova.
Genes & Development (2007)
Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs
Rui Yi;Dónal O'Carroll;Hilda A Pasolli;Zhihong Zhang.
Nature Genetics (2006)
Histone H3 lysine 9 methylation is an epigenetic imprint of facultative heterochromatin.
Antoine H F M Peters;Jacqueline E Mermoud;Dónal O'Carroll;Dónal O'Carroll;Michaela Pagani.
Nature Genetics (2002)
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