Claus Nerlov

Overview

Best Publications

• A CREB-C/EBPbeta cascade induces M2 macrophage-specific gene expression and promotes muscle injury repair.

  Daniela Ruffell;Foteini Mourkioti;Adriana Gambardella;Peggy Kirstetter

  787
  Citations

• Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy

  Alejandra Sanjuan-Pla;Iain C. Macaulay;Christina T. Jensen;Petter S. Woll

  648
  Citations

• Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal

  Eric M. Pietras;Cristina Mirantes-Barbeito;Sarah Fong;Dirk Loeffler

  604
  Citations

• Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block

  Peggy Kirstetter;Kristina Anderson;Bo T Porse;Sten Eirik W Jacobsen

  579
  Citations

• DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction

  Ann-Marie Bröske;Lena Vockentanz;Shabnam Kharazi;Matthew R Huska

  520
  Citations

• c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II.

  Lin-Heng Li;C. Nerlov;G. Prendergast;D. Macgregor

  430
  Citations

• E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo.

  Bo T. Porse;Thomas Å. Pedersen;Xiufeng Xu;Bo Lindberg

  400
  Citations

• Myelodysplastic Syndromes Are Propagated by Rare and Distinct Human Cancer Stem Cells In Vivo

  Petter S. Woll;Una Kjällquist;Onima Chowdhury;Helen Doolittle

  371
  Citations

• Hierarchically related lineage-restricted fates of multipotent haematopoietic stem cells.

  Joana Carrelha;Yiran Meng;Laura M. Kettyle;Tiago C. Luis

  343
  Citations

• Genetic pathways in therapy-related myelodysplasia and acute myeloid leukemia.

  Jens Pedersen-Bjergaard;Mette K. Andersen;Debes H. Christiansen;Claus Nerlov

  343
  Citations

• Modeling of C/EBPalpha mutant acute myeloid leukemia reveals a common expression signature of committed myeloid leukemia-initiating cells.

  Peggy Kirstetter;Mikkel B Schuster;Oksana Bereshchenko;Susan Moore

  306
  Citations

• Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells.

  Amit Grover;Alejandra Sanjuan-Pla;Alejandra Sanjuan-Pla;Supat Thongjuea;Joana Carrelha;Joana Carrelha

  303
  Citations

• NMD is essential for hematopoietic stem and progenitor cells and for eliminating by-products of programmed DNA rearrangements

  Joachim Weischenfeldt;Inge Damgaard;David Bryder;Kim Theilgaard-Mönch

  297
  Citations

• Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging

  Ya-Hsuan Ho;Raquel del Toro;José Rivera-Torres;Justyna Rak

  247
  Citations

• Disease evolution and outcomes in familial AML with germline CEBPA mutations

  Kiran Tawana;Jun Wang;Aline Renneville;Aline Renneville;Csaba Bödör

  243
  Citations

• Distinct myeloid progenitor-differentiation pathways identified through single-cell RNA sequencing

  Roy Drissen;Roy Drissen;Natalija Buza-Vidas;Petter Woll;Supat Thongjuea

  238
  Citations

• Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia

  Florian Grebien;Masoud Vedadi;Masoud Vedadi;Matthäus Getlik;Roberto Giambruno

  231
  Citations

• Early myeloid lineage choice is not initiated by random PU.1 to GATA1 protein ratios.

  Philipp S. Hoppe;Michael Schwarzfischer;Dirk Loeffler;Konstantinos D. Kokkaliaris

  219
  Citations

• Myeloid and lymphoid contribution to non-haematopoietic lineages through irradiation-induced heterotypic cell fusion.

  Jens Martin Nygren;Karina Liuba;Martin Breitbach;Simon Stott

  206
  Citations

• Hierarchically Related Lineage-Restricted Fates of Multipotent Hematopoietic Stem Cells

  Joana Carrelha;Yiran Meng;Laura Kettyle;Tiago Luis

  1
  Citations