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Frank J.T. Staal

D-Index & Metrics

Biology and Biochemistry

D-Index
73
Citations
21201
World Ranking
5887
National Ranking
148

Frank J.T. Staal publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Frank J.T. Staal sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 218 publications — 57th percentile

57% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Frank J.T. Staal D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Frank J.T. Staal sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 73 D-Index — 71st percentile

71% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Frank J.T. Staal is affiliated with Leiden University Medical Center in the Netherlands. Their research spans various intersecting fields including Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. The primary subfields of their work include Molecular Biology, Immunology, Oncology, Genetics, and Infectious Diseases.

The scientist's research topics cover a range of contemporary biomedical themes such as CAR-T cell therapy research, CRISPR and Genetic Engineering, Immune Cell Function and Interaction, Virus-based gene therapy research, T-cell and B-cell Immunology, SARS-CoV-2 and COVID-19 Research, and Immunodeficiency and Autoimmune Disorders.

Frequent coauthors collaborating with Frank J.T. Staal include:

  • Karin Pike-Overzet
  • Kirsten Canté-Barrett
  • Jacques J. M. van Dongen
  • Arjan C. Lankester
  • Sandra A. Vloemans

The scientist has published extensively, with a concentration of papers appearing in venues such as Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, Frontiers in Immunology, Cells, Cancer Cell, and Frontiers in Cell and Developmental Biology.

Notable recent publications include:

  • "An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates" (2020, Cancer Cell)
  • "Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis" (2020, Cell Metabolism)
  • "Inflammation and Wnt Signaling: Target for Immunomodulatory Therapy?" (2021, Frontiers in Cell and Developmental Biology)
  • "An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates" (2020, Cancer Cell)
  • "Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8+ T cell responses following COVID-19" (2021, Nature Immunology)

Best Publications

  • Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients

    Steven J. Howe;Marc R. Mansour;Kerstin Schwarzwaelder;Cynthia Bartholomae

  • Intracellular thiols regulate activation of nuclear factor kappa B and transcription of human immunodeficiency virus

    F J Staal;M Roederer;L A Herzenberg

  • Endothelial Progenitor Cell Dysfunction: A Novel Concept in the Pathogenesis of Vascular Complications of Type 1 Diabetes

    Cindy J.M. Loomans;Eelco J.P. de Koning;Frank J.T. Staal;Maarten B. Rookmaaker

  • WNT signalling in the immune system: WNT is spreading its wings.

    Frank J. T. Staal;Tiago C. Luis;Machteld M. Tiemessen

  • Cytokine-stimulated human immunodeficiency virus replication is inhibited by N-acetyl-L-cysteine.

    M. Roederer;F. J. T. Staal;P. A. Raju;S. W. Ela

  • Glutathione deficiency and human immunodeficiency virus infection.

    F.J.T Staal;S.W Ela;M Roederer;M.T Anderson

  • Separation of oxidant-initiated and redox-regulated steps in the NF-kappa B signal transduction pathway

    M. T. Anderson;F. J. T. Staal;C. Gitler;L. A. Herzenberg

  • WNT signalling and haematopoiesis: a WNT-WNT situation.

    Frank J.T. Staal;Hans C. Clevers

  • New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling

    Willem A. Dik;Karin Pike-Overzet;Floor Weerkamp;Dick de Ridder;Dick de Ridder

  • Integrated Transcript and Genome Analyses Reveal NKX2-1 and MEF2C as Potential Oncogenes in T Cell Acute Lymphoblastic Leukemia

    Irene Homminga;Rob Pieters;Anton W. Langerak;Johan J. de Rooi

  • Wnt signals are transmitted through N‐terminally dephosphorylated β‐catenin

    Frank J T Staal;Mascha van Noort;Ger J Strous;Hans C Clevers

  • A discriminating messenger RNA signature for bipolar disorder formed by an aberrant expression of inflammatory genes in monocytes.

    Roos C. Padmos;Manon H. J. Hillegers;Esther M. Knijff;Ronald Vonk

  • Canonical Wnt Signaling Regulates Hematopoiesis in a Dosage-Dependent Fashion

    Tiago C. Luis;Tiago C. Luis;Brigitta A.E. Naber;Brigitta A.E. Naber;Paul P.C. Roozen;Martijn H. Brugman

  • An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates

    Jermaine Goveia;Katerina Rohlenova;Federico Taverna;Lucas Treps

  • Chance or necessity? Insertional mutagenesis in gene therapy and its consequences

    Christopher Baum;Christof von Kalle;Frank J.T Staal;Zhixiong Li

  • Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy

    Annette Deichmann;Salima Hacein-Bey-Abina;Manfred Schmidt;Manfred Schmidt;Alexandrine Garrigue

  • Redox regulation of signal transduction: tyrosine phosphorylation and calcium influx

    F. J. T. Staal;M. T. Anderson;G. E. J. Staal;L. A. Herzenberg

  • Wnt signaling is required for thymocyte development and activates Tcf-1 mediated transcription

    Frank J. T. Staal;Jan Meeldijk;Petra Moerer;Philippe Jay

  • CD34+CD38dim cells in the human thymus can differentiate into T, natural killer, and dendritic cells but are distinct from pluripotent stem cells

    P Res;E Martinez-Caceres;A Cristina Jaleco;F Staal

  • Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo

    Kerstin Schwarzwaelder;Steven J. Howe;Manfred Schmidt;Manfred Schmidt;Martijn H. Brugman

Frequent Co-Authors

Jacques J.M. van Dongen
Jacques J.M. van Dongen Leiden University Medical Center
Leonore A. Herzenberg
Leonore A. Herzenberg Stanford University
Willem E. Fibbe
Willem E. Fibbe Leiden University Medical Center
Anton W. Langerak
Anton W. Langerak Erasmus University Rotterdam
Marcel J. T. Reinders
Marcel J. T. Reinders Delft University of Technology
Leonard A. Herzenberg
Leonard A. Herzenberg Stanford University
Hans Clevers
Hans Clevers Hubrecht Institute for Developmental Biology and Stem Cell Research
Adrian J. Thrasher
Adrian J. Thrasher University College London
Mario Roederer
Mario Roederer National Institute of Allergy and Infectious Diseases
Arjan C. Lankester
Arjan C. Lankester Leiden University Medical Center

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Best Scientists Citing Frank J.T. Staal

Adrian J. Thrasher

Adrian J. Thrasher

University College London

Publications: 96

Axel Schambach

Axel Schambach

Hannover Medical School

Publications: 77

Christopher Baum

Christopher Baum

Charité - University Medicine Berlin

Publications: 58

Marina Cavazzana-Calvo

Marina Cavazzana-Calvo

Necker-Enfants Malades Hospital

Publications: 47

Manfred Schmidt

Manfred Schmidt

German Cancer Research Center

Publications: 47

Alain Fischer

Alain Fischer

Collège de France

Publications: 43

Christof von Kalle

Christof von Kalle

Charité - University Medicine Berlin

Publications: 39

Hemmo A. Drexhage

Hemmo A. Drexhage

Erasmus University Rotterdam

Publications: 36

Tom Taghon

Tom Taghon

Ghent University

Publications: 36

Jacques J.M. van Dongen

Jacques J.M. van Dongen

Leiden University Medical Center

Publications: 36

Alessandro Aiuti

Alessandro Aiuti

Vita-Salute San Raffaele University

Publications: 35

Cynthia E. Dunbar

Cynthia E. Dunbar

National Institutes of Health

Publications: 32

Ellen V. Rothenberg

Ellen V. Rothenberg

California Institute of Technology

Publications: 32

Donald B. Kohn

Donald B. Kohn

University of California, Los Angeles

Publications: 29

Menno C. van Zelm

Menno C. van Zelm

Monash University

Publications: 28

Frederic D. Bushman

Frederic D. Bushman

University of Pennsylvania

Publications: 27

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