What is he best known for?
The fields of study he is best known for:
- Gene
- Immune system
- Genetics
Cell biology, Immunology, Wnt signaling pathway, Molecular biology and Progenitor cell are his primary areas of study.
His Cell biology research focuses on Stem cell and Signal transduction.
His work deals with themes such as Peripheral blood mononuclear cell, Internal medicine, Intracellular and Endocrinology, which intersect with Immunology.
His Wnt signaling pathway research is multidisciplinary, incorporating perspectives in Cell growth, Haematopoiesis, Cellular differentiation and Immune system.
Frank J.T. Staal has researched Molecular biology in several fields, including Gene rearrangement, Gene expression, Gene expression profiling, T cell and Transcription factor.
Frank J.T. Staal studied Progenitor cell and Transplantation that intersect with Stem cell factor, Hematopoietic stem cell, CD34 and CD3.
His most cited work include:
- Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients (912 citations)
- Intracellular thiols regulate activation of nuclear factor kappa B and transcription of human immunodeficiency virus (836 citations)
- Endothelial Progenitor Cell Dysfunction: A Novel Concept in the Pathogenesis of Vascular Complications of Type 1 Diabetes (760 citations)
What are the main themes of his work throughout his whole career to date?
His main research concerns Cell biology, Immunology, Stem cell, Haematopoiesis and Wnt signaling pathway.
His studies deal with areas such as T cell, Cell, Genetics and Cellular differentiation as well as Cell biology.
His T cell research focuses on Transcription factor and how it connects with Molecular biology and Transcription.
His Stem cell research incorporates themes from Cancer research, Transplantation and Adult stem cell.
The study incorporates disciplines such as Myeloid, Bone marrow and Homeostasis in addition to Haematopoiesis.
His Wnt signaling pathway research incorporates themes from Lymphopoiesis and Thymocyte.
He most often published in these fields:
- Cell biology (39.18%)
- Immunology (31.44%)
- Stem cell (34.02%)
What were the highlights of his more recent work (between 2017-2021)?
- Cell biology (39.18%)
- Stem cell (34.02%)
- Haematopoiesis (27.84%)
In recent papers he was focusing on the following fields of study:
His primary areas of study are Cell biology, Stem cell, Haematopoiesis, Immune system and Cancer research.
A large part of his Cell biology studies is devoted to Progenitor cell.
The study incorporates disciplines such as Hedgehog signaling pathway, Transforming growth factor, Genetic enhancement and Lymphocyte in addition to Stem cell.
His Haematopoiesis research incorporates elements of Niche, Wnt signaling pathway, Myeloid, Blood cell and In vivo.
Wnt signaling pathway is the subject of his research, which falls under Signal transduction.
His Cancer research research is multidisciplinary, incorporating perspectives in Neuroinflammation, Cell fate determination, Gene knockdown and MEDLINE.
Between 2017 and 2021, his most popular works were:
- An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates (53 citations)
- Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis. (31 citations)
- Ex Vivo Expansion of Hematopoietic Stem Cells for Therapeutic Purposes: Lessons from Development and the Niche. (27 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Immune system
- Genetics
His scientific interests lie mostly in Cell biology, Gene expression, Cancer research, Transplantation and Stem cell.
Frank J.T. Staal interconnects Endothelial stem cell, Phenotype, Angiogenesis and Transcription factor in the investigation of issues within Gene expression.
Frank J.T. Staal combines subjects such as Ex vivo and Genetic enhancement with his study of Transplantation.
His Stem cell research includes themes of HEK 293 cells, Regulation of gene expression and Wnt signaling pathway, Signal transduction.
His studies in Haematopoiesis integrate themes in fields like Cell type and WNT3A.
His Gene study combines topics in areas such as Apoptosis and T cell.
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