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Overview

Arjan C. Lankester is affiliated with Leiden University Medical Center in the Netherlands. Their research primarily focuses on the fields of medicine, immunology, and microbiology with a significant emphasis on hematology and immunology within these areas.

Their work spans several subfields, including hematology, immunology, genetics, public health, environmental and occupational health, and pediatrics, perinatology and child health. The main research topics addressed by Lankester encompass hematopoietic stem cell transplantation, acute lymphoblastic leukemia research, immunodeficiency and autoimmune disorders, immune cell function and interaction, acute myeloid leukemia research, childhood cancer survivors' quality of life, and hemoglobinopathies and related disorders.

Frequent publication venues for their research include:

  • Bone Marrow Transplantation
  • Blood
  • Journal of Clinical Immunology
  • Transplantation and Cellular Therapy
  • Journal of Allergy and Clinical Immunology

Lankester has collaborated extensively with various researchers, most notably Bénédicte Neven, Andrew R. Gennery, Michael H. Albert, Frans J. Smiers, and Erik G. J. von Asmuth.

Selected recent papers illustrate the scope and focus of their research contributions:

  • EBMT/ESID inborn errors working party guidelines for hematopoietic stem cell transplantation for inborn errors of immunity, 2021, Bone Marrow Transplantation
  • Hematopoietic cell transplantation and cellular therapy survey of the EBMT: monitoring of activities and trends over 30 years, 2021, Bone Marrow Transplantation
  • Indications for haematopoietic cell transplantation for haematological diseases, solid tumours and immune disorders: current practice in Europe, 2022, Bone Marrow Transplantation
  • The challenge of COVID-19 and hematopoietic cell transplantation; EBMT recommendations for management of hematopoietic cell transplant recipients, their donors, and patients undergoing CAR T-cell therapy, 2020, Bone Marrow Transplantation
  • The EBMT activity survey on hematopoietic-cell transplantation and cellular therapy 2018: CAR-T's come into focus, 2020, Bone Marrow Transplantation

The concentration of publications in Bone Marrow Transplantation and related journals underlines a specialized interest in transplantation and cellular therapy within hematology and immunology. Their research covers both clinical guidelines and epidemiological surveys, reflecting involvement in both practical and systemic aspects of hematopoietic stem cell transplantation and associated immune disorders.

Best Publications

  • Cotransplantation of ex vivo expanded mesenchymal stem cells accelerates lymphocyte recovery and may reduce the risk of graft failure in haploidentical hematopoietic stem-cell transplantation.

    Lynne M. Ball;Maria Ester Bernardo;Helene Roelofs;Arjan Lankester

  • Tumor-Infiltrating Macrophages Are Associated with Metastasis Suppression in High-Grade Osteosarcoma: A Rationale for Treatment with Macrophage Activating Agents

    Emilie P. Buddingh;Marieke L. Kuijjer;Ronald A J Duim;Horst Bürger

  • Prevalence, clinical characteristics, and prognosis of GATA2-related myelodysplastic syndromes in children and adolescents.

    Marcin W. Wlodarski;Marcin W. Wlodarski;Shinsuke Hirabayashi;Victor Pastor;Jan Starý

  • Hematopoietic cell transplantation and cellular therapy survey of the EBMT: monitoring of activities and trends over 30 years

    Jakob R. Passweg;Helen Baldomero;Christian Chabannon;Grzegorz W. Basak

  • X-linked lymphoproliferative disease due to SAP/SH2D1A deficiency: a multicenter study on the manifestations, management, and outcome of the disease

    Claire Booth;Kimberly C. Gilmour;Paul Veys;Andrew R. Gennery

  • Association between anti-thymocyte globulin exposure and CD4+ immune reconstitution in paediatric haemopoietic cell transplantation: a multicentre, retrospective pharmacodynamic cohort analysis

    Rick Admiraal;Charlotte van Kesteren;Charlotte van Kesteren;Cornelia M Jol-van der Zijde;Arjan C Lankester

  • Death after hematopoietic stem cell transplantation: changes over calendar year time, infections and associated factors.

    Jan Styczyński;Gloria Tridello;Linda Koster;Simona Iacobelli

  • Indications for haematopoietic stem cell transplantation for haematological diseases, solid tumours and immune disorders: current practice in Europe, 2019

    Rafael F. Duarte;Myriam Labopin;Peter Bader;Grzegorz W. Basak

  • Diagnosis and severity criteria for sinusoidal obstruction syndrome/veno-occlusive disease in pediatric patients

    S. Corbacioglu;E. Carreras;M. Ansari;A. Balduzzi

  • Multiple infusions of mesenchymal stromal cells induce sustained remission in children with steroid‐refractory, grade III–IV acute graft‐versus‐host disease

    Lynne M. Ball;Maria E. Bernardo;Helene Roelofs;Maarten J. D. van Tol

  • Co-infusion of ex vivo-expanded, parental MSCs prevents life-threatening acute GVHD, but does not reduce the risk of graft failure in pediatric patients undergoing allogeneic umbilical cord blood transplantation.

    M E Bernardo;L M Ball;A M Cometa;H Roelofs

  • Total Body Irradiation or Chemotherapy Conditioning in Childhood ALL: A Multinational, Randomized, Noninferiority Phase III Study.

    Christina Peters;Jean-Hugues Dalle;Franco Locatelli;Ulrike Poetschger

  • Human Circulating and Tissue-Resident CD56(bright) Natural Killer Cell Populations.

    Janine E. Melsen;Gertjan Lugthart;Arjan C. Lankester;Marco W. Schilham

  • Outcomes of allogeneic haematopoietic stem cell transplantation from HLA-matched and alternative donors: a European Society for Blood and Marrow Transplantation registry retrospective analysis.

    Roni Shouval;Joshua A. Fein;Myriam Labopin;Nicolaus Kröger

  • Mesenchymal stem cells exert differential effects on alloantigen and virus-specific T-cell responses

    Helen Karlsson;Sujith Samarasinghe;Lynne M. Ball;Berit Sundberg

  • The challenge of COVID-19 and hematopoietic cell transplantation; EBMT recommendations for management of hematopoietic cell transplant recipients, their donors, and patients undergoing CAR T-cell therapy.

    Per Ljungman;Per Ljungman;Malgorzata Mikulska;Rafael de la Camara;Grzegorz W Basak

  • Internally Controlled Real-Time PCR Monitoring of Adenovirus DNA Load in Serum or Plasma of Transplant Recipients

    Eric C. J. Claas;Marco W. Schilham;Caroline S. de Brouwer;Petr Hubacek

  • Ig gene rearrangement steps are initiated in early human precursor B cell subsets and correlate with specific transcription factor expression

    Menno C. van Zelm;Mirjam van der Burg;Dick de Ridder;Barbara H. Barendregt

  • Mutations in ZBTB24 are associated with immunodeficiency, centromeric instability, and facial anomalies syndrome type 2

    Jessica C. de Greef;Jun Wang;Judit Balog;Johan T. den Dunnen

  • High levels of adenovirus DNA in serum correlate with fatal outcome of adenovirus infection in children after allogeneic stem-cell transplantation.

    Marco W. Schilham;Eric C. Claas;Wouter van Zaane;Bianca Heemskerk

Frequent Co-Authors

Robbert G. M. Bredius
Robbert G. M. Bredius Leiden University Medical Center
Marco W. Schilham
Marco W. Schilham Leiden University Medical Center
Peter Bader
Peter Bader Goethe University Frankfurt
Andrew R. Gennery
Andrew R. Gennery Newcastle University
Paul Veys
Paul Veys Great Ormond Street Hospital
Marco Zecca
Marco Zecca University of Pavia
Mary Slatter
Mary Slatter Newcastle University
Pancras C.W. Hogendoorn
Pancras C.W. Hogendoorn Leiden University Medical Center
Henk-Jan Guchelaar
Henk-Jan Guchelaar Leiden University Medical Center
Nicolaus Kröger
Nicolaus Kröger Universität Hamburg

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