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D-Index
92
Citations
40698
World Ranking
11129
National Ranking
438

Overview

Willem E. Fibbe is affiliated with Leiden University Medical Center in the Netherlands. Their research primarily spans the field of Medicine with a focus on Genetics, Surgery, Hematology, Immunology, and Oncology as subfields of study.

The scientist's main research interests include mesenchymal stem cell research, tissue engineering and regenerative medicine, pancreatic function and diabetes, hematopoietic stem cell transplantation, CAR-T cell therapy research, biomedical ethics and regulation, and renal transplantation outcomes and treatments.

Willem E. Fibbe has contributed to several recent publications, including:

  • Safety and Preliminary Efficacy of Mesenchymal Stromal Cell (ORBCEL-M) Therapy in Diabetic Kidney Disease: A Randomized Clinical Trial (NEPHSTROM), 2023, Journal of the American Society of Nephrology
  • Human leukocyte antigen selected allogeneic mesenchymal stromal cell therapy in renal transplantation: The Neptune study, a phase I single-center study, 2020, American Journal of Transplantation
  • Autologous bone marrow-derived mesenchymal stromal cell therapy with early tacrolimus withdrawal: The randomized prospective, single-center, open-label TRITON study, 2021, American Journal of Transplantation
  • Cytokine Mixtures Mimicking the Local Milieu in Patients with Inflammatory Bowel Disease Impact Phenotype and Function of Mesenchymal Stromal Cells, 2022, Stem Cells Translational Medicine
  • A unique immune signature in blood separates therapy-refractory from therapy-responsive acute graft-versus-host disease, 2022, Blood

Their frequent coauthors include Melissa van Pel, Dominique Bonnet, Simón Méndez-Ferrer, Sjaak Philipsen, and Jan Jacob Schuringa.

Willem E. Fibbe regularly publishes in scientific journals such as:

  • Journal of the American Society of Nephrology
  • American Journal of Transplantation
  • Blood
  • Experimental Hematology
  • Stem Cells Translational Medicine

Best Publications

  • Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study.

    Katarina Le Blanc;Francesco Frassoni;Lynne Ball;Franco Locatelli

  • Immunomodulatory properties of mesenchymal stromal cells.

    Alma J. Nauta;Willem E. Fibbe

  • Isolation of Mesenchymal Stem Cells of Fetal or Maternal Origin from Human Placenta

    Pieternella S. in 't Anker;Sicco A. Scherjon;Carin Kleijburg‐van der Keur;Godelieve M.J.S. de Groot‐Swings

  • Mesenchymal stromal cells: sensors and switchers of inflammation.

    Maria Ester Bernardo;Willem E. Fibbe

  • Amniotic fluid as a novel source of mesenchymal stem cells for therapeutic transplantation

    Pieternella S. in `t Anker;Sicco A. Scherjon;Carin Kleijburg-van der Keur;Willy A. Noort

  • Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins

    A. H. Schinkel;U. Mayer;E. Wagenaar;C. A. A. M. Mol

  • Mesenchymal Stem Cells Inhibit Generation and Function of Both CD34+-Derived and Monocyte-Derived Dendritic Cells

    Alma J. Nauta;Alwine B. Kruisselbrink;Ellie Lurvink;Roel Willemze

  • Donor-derived mesenchymal stem cells are immunogenic in an allogeneic host and stimulate donor graft rejection in a nonmyeloablative setting

    Alma J. Nauta;Geert Westerhuis;Alwine B. Kruisselbrink;Ellie G. A. Lurvink

  • Sarcoma derived from cultured mesenchymal stem cells

    Jakub Tolar;Alma J. Nauta;Mark J. Osborn;Angela Panoskaltsis Mortari

  • Autologous Hematopoietic Stem Cell Transplantation vs Intravenous Pulse Cyclophosphamide in Diffuse Cutaneous Systemic Sclerosis: A Randomized Clinical Trial

    J.M. van Laar;D. Farge;J.K. Sont;K. Naraghi

  • Autologous bone marrow-derived mesenchymal stromal cell treatment for refractory luminal Crohn's disease: results of a phase I study

    Marjolijn Duijvestein;Anne Christine W Vos;Helene Roelofs;Manon E Wildenberg

  • Human fetal lymphoid tissue–inducer cells are interleukin 17–producing precursors to RORC + CD127 + natural killer–like cells

    Tom Cupedo;Natasha K Crellin;Natalie Papazian;Elwin J Rombouts

  • Cotransplantation of ex vivo expanded mesenchymal stem cells accelerates lymphocyte recovery and may reduce the risk of graft failure in haploidentical hematopoietic stem-cell transplantation.

    Lynne M. Ball;Maria Ester Bernardo;Helene Roelofs;Arjan Lankester

  • Mesenchymal stem cells in human second-trimester bone marrow, liver, lung, and spleen exhibit a similar immunophenotype but a heterogeneous multilineage differentiation potential

    in 't Anker Ps;Noort Wa;Scherjon Sa;Kleijburg-van der Keur C

  • Mesenchymal stem cells promote engraftment of human umbilical cord blood–derived CD34+ cells in NOD/SCID mice

    Willy A Noort;Alwine B Kruisselbrink;Pieternella S in't Anker;Marjolein Kruger

  • Adipose Tissue-Derived Multipotent Stromal Cells Have a Higher Immunomodulatory Capacity Than Their Bone Marrow-Derived Counterparts

    Sara M. Melief;Jaap Jan Zwaginga;Willem E. Fibbe;Helene Roelofs

  • International Society for Cellular Therapy perspective on immune functional assays for mesenchymal stromal cells as potency release criterion for advanced phase clinical trials

    Jacques Galipeau;Mauro Krampera;John Barrett;Francesco Dazzi

  • Isolation of functionally distinct mesenchymal stem cell subsets using antibodies against CD56, CD271, and mesenchymal stem cell antigen-1

    Venkata Lokesh Battula;Sabrina Treml;Petra M. Bareiss;Friederike Gieseke

  • Risk of tumorigenicity in mesenchymal stromal cell-based therapies--bridging scientific observations and regulatory viewpoints.

    Lisbeth Barkholt;Lisbeth Barkholt;Egbert Flory;Egbert Flory;Veronika Jekerle;Sophie Lucas-Samuel

  • Multipotent Stromal Cells Induce Human Regulatory T Cells Through a Novel Pathway Involving Skewing of Monocytes Toward Anti-inflammatory Macrophages

    Sara M. Melief;Ellen Schrama;Martijn H. Brugman;Machteld M. Tiemessen

Frequent Co-Authors

Roel Willemze
Roel Willemze Leiden University Medical Center
Martin J. Schalij
Martin J. Schalij Leiden University Medical Center
Jaap Jan Zwaginga
Jaap Jan Zwaginga Leiden University Medical Center
Jeroen J. Bax
Jeroen J. Bax Leiden University Medical Center
Frank J.T. Staal
Frank J.T. Staal Leiden University Medical Center
Ghislain Opdenakker
Ghislain Opdenakker Rega Institute for Medical Research
Albert de Roos
Albert de Roos Leiden University Medical Center
J.H. Frederik Falkenburg
J.H. Frederik Falkenburg Leiden University Medical Center
Anneke Brand
Anneke Brand Leiden University Medical Center
Katarina Le Blanc
Katarina Le Blanc Karolinska University Hospital

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