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Biology and Biochemistry

D-Index
75
Citations
56156
World Ranking
5177
National Ranking
74

Overview

Katarina Le Blanc is affiliated with Karolinska University Hospital in Sweden. Their research primarily focuses on Medicine, with contributions spanning Genetics, Surgery, Pulmonary and Respiratory Medicine, Oncology, and Hematology. The scientist's work shows a significant focus on Mesenchymal stem cell research and related biomedical fields.

Their main topics of study include:

  • Mesenchymal stem cell research
  • Tissue Engineering and Regenerative Medicine
  • Neonatal Respiratory Health Research
  • Hematopoietic Stem Cell Transplantation
  • Biomedical Ethics and Regulation
  • Extracellular vesicles in disease
  • Cancer-related cognitive impairment studies

Frequent collaborators in their research are:

  • Mauro Krampera
  • Ellen Iacobaeus
  • Nadir Kadri
  • Erik Boberg
  • Jacques Galipeau

The scientist has published extensively in various academic journals, with a notable presence in Cytotherapy and Bone Marrow Transplantation. Other journals include Cell Stem Cell, The Lancet Neurology, and Cellular and Molecular Immunology. Their publication record reflects contributions across clinical and translational medicine spheres.

Selected recent papers include:

  • "Mesenchymal stromal cells: Putative microenvironmental modulators become cell therapy," 2021, Cell Stem Cell
  • "Safety, tolerability, and activity of mesenchymal stem cells versus placebo in multiple sclerosis (MESEMS): a phase 2, randomised, double-blind crossover trial," 2021, The Lancet Neurology
  • "Current perspectives on mesenchymal stromal cell therapy for graft versus host disease," 2023, Cellular and Molecular Immunology
  • "Treatment of chronic GvHD with mesenchymal stromal cells induces durable responses: A phase II study," 2020, Stem Cells Translational Medicine
  • "ISCT MSC committee statement on the US FDA approval of allogenic bone-marrow mesenchymal stromal cells," 2025, Cytotherapy

The scientific contributions of Katarina Le Blanc focus on the clinical applications and therapeutic potential of mesenchymal stromal cells, particularly in immune modulation and regenerative therapies. Their work intersects with multiple disciplines and addresses both experimental and clinical challenges in stem cell therapy.

Best Publications

  • Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement

    M. Dominici;K. Le Blanc;I. Mueller;I. Slaper-Cortenbach

  • Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells

    Katarina Le Blanc;Ida Rasmusson;Berit Sundberg;Cecilia Götherström

  • Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study.

    Katarina Le Blanc;Francesco Frassoni;Lynne Ball;Franco Locatelli

  • HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells.

    Katarina Le Blanc;Charlotte Tammik;Kerstin Rosendahl;Eva Zetterberg

  • Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex.

    K. Le Blanc;L. Tammik;B. Sundberg;S. E. Haynesworth

  • Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting

    Oscar P. B. Wiklander;Joel Z. Nordin;Aisling O'Loughlin;Ylva Gustafsson

  • Multipotent mesenchymal stromal cells and the innate immune system

    Katarina Le Blanc;Dimitrios Mougiakakos

  • Immunomodulation by mesenchymal stem cells and clinical experience

    K. Le Blanc;O. Ringdén

  • Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytes or natural killer cells.

    Ida Rasmusson;Olle Ringdén;Berit Sundberg;Katarina Le Blanc

  • Mesenchymal stem cells inhibit lymphocyte proliferation by mitogens and alloantigens by different mechanisms

    Ida Rasmusson;Olle Ringdén;Berit Sundberg;Katarina Le Blanc

  • Immunobiology of Human Mesenchymal Stem Cells and Future Use in Hematopoietic Stem Cell Transplantation

    Katarina Le Blanc;Olle Ringdén

  • Transplantation of mesenchymal stem cells to enhance engraftment of hematopoietic stem cells.

    K. Le Blanc;H. Samuelsson;B. Gustafsson;M. Remberger

  • Fetal mesenchymal stem-cell engraftment in bone after in utero transplantation in a patient with severe osteogenesis imperfecta.

    Katarina Le Blanc;Cecilia Götherström;Olle Ringdén;Moustapha Hassan

  • Mesenchymal Stem Cells Inhibit the Expression of CD25 (Interleukin‐2 Receptor) and CD38 on Phytohaemagglutinin‐Activated Lymphocytes

    K Le Blanc;I Rasmusson;C Götherström;C Seidel

  • Concise review: hitting the right spot with mesenchymal stromal cells.

    Jakub Tolar;Katarina Le Blanc;Armand Keating;Bruce R. Blazar

  • Functional studies of mesenchymal stem cells derived from adult human adipose tissue.

    Andrea Dicker;Katarina Le Blanc;Gaby Åström;Vanessa van Harmelen

  • Xenoreactivity and engraftment of human mesenchymal stem cells transplanted into infarcted rat myocardium.

    K.H Grinnemo;A Månsson;G Dellgren;D Klingberg

  • Do Cryopreserved Mesenchymal Stromal Cells Display Impaired Immunomodulatory and Therapeutic Properties

    Guido Moll;Jessica J. Alm;Lindsay C. Davies;Lena von Bahr

  • Mesenchymal Stem Cells Stimulate Antibody Secretion in Human B Cells

    Ida Rasmusson;K Le Blanc;K Le Blanc;B Sundberg;B Sundberg;O Ringdén;O Ringdén

  • Long-Term Complications, Immunologic Effects, and Role of Passage for Outcome in Mesenchymal Stromal Cell Therapy

    Lena von Bahr;Berit Sundberg;Lena Lönnies;Birgitta Sander

Frequent Co-Authors

Olle Ringdén
Olle Ringdén Karolinska Institute
Per Ljungman
Per Ljungman Karolinska University Hospital
Willem E. Fibbe
Willem E. Fibbe Leiden University Medical Center
A. John Barrett
A. John Barrett National Institutes of Health
Olle Korsgren
Olle Korsgren Uppsala University
Bo Nilsson
Bo Nilsson Uppsala University
Francesco Dazzi
Francesco Dazzi King's College London
Rolf Kiessling
Rolf Kiessling Karolinska Institute
Arjan C. Lankester
Arjan C. Lankester Leiden University Medical Center
Claes Örvell
Claes Örvell Karolinska University Hospital

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