Mark Lawler

Overview

Best Publications

• Effect of delays in the 2-week-wait cancer referral pathway during the COVID-19 pandemic on cancer survival in the UK: a modelling study.

  Amit Sud;Bethany Torr;Michael E Jones;John Broggio

  491
  Citations

• Integrating Genomics into Healthcare: A Global Responsibility

  Zornitza Stark;Lena Dolman;Teri A. Manolio;Brad Ozenberger

  370
  Citations

• Activated protein C inhibits lipopolysaccharide-induced nuclear translocation of nuclear factor kappaB (NF-kappaB) and tumour necrosis factor alpha (TNF-alpha) production in the THP-1 monocytic cell line.

  B. White;M. Schmidt;C. Murphy;W. Livingstone

  321
  Citations

• Autosomal dominant retinitis pigmentosa (ADRP): Localization of an ADRP gene to the long arm of chromosome 3

  Peter McWilliam;G.Jane Farrar;Paul Kenna;Daniel G. Bradley

  306
  Citations

• Estimated impact of the COVID-19 pandemic on cancer services and excess 1-year mortality in people with cancer and multimorbidity: near real-time data on cancer care, cancer deaths and a population-based cohort study.

  Alvina G Lai;Laura Pasea;Amitava Banerjee;Amitava Banerjee;Geoff Hall;Geoff Hall

  282
  Citations

• Evaluation of mixed chimerism by in vitro amplification of dinucleotide repeat sequences using the polymerase chain reaction

  M Lawler;P Humphries;SR McCann

  224
  Citations

• Expression of the NF‐κB targets BCL2 and BIRC5/Survivin characterizes small B‐cell and aggressive B‐cell lymphomas, respectively

  Lorraine Tracey;Alberto Pérez-Rosado;Maria Jesús Artiga;Francisca I Camacho

  211
  Citations

• Cyclosporin A and short-term methotrexate versus cyclosporin A as graft versus host disease prophylaxis in patients with severe aplastic anemia given allogeneic bone marrow transplantation from an HLA-identical sibling: results of a GITMO/EBMT randomized trial.

  F Locatelli;B Bruno;M Zecca;M T Van-Lint

  199
  Citations

• Mycosis fungoides shows concurrent deregulation of multiple genes involved in the TNF signaling pathway: an expression profile study

  Lorraine Tracey;Raquel Villuendas;Ana Maria Dotor;Inmaculada Spiteri

  184
  Citations

• 4-Amino-1,8-naphthalimide-based Tröger's bases as high affinity DNA targeting fluorescent supramolecular scaffolds

  Emma B Veale;Daniel O Frimannsson;Mark Lawler;Thorfinnur Gunnlaugsson

  175
  Citations

• Targeting c-MET in gastrointestinal tumours: rationale, opportunities and challenges

  Conor A Bradley;Manuel Salto-Tellez;Manuel Salto-Tellez;Pierre Laurent-Puig;Alberto Bardelli

  174
  Citations

• Estimating excess mortality in people with cancer and multimorbidity in the COVID-19 emergency

  Alvina G. Lai;Laura Pasea;Amitava Banerjee;Amitava Banerjee;Spiros Denaxas

  171
  Citations

• Challenging the Cancer Molecular Stratification Dogma: Intratumoral Heterogeneity Undermines Consensus Molecular Subtypes and Potential Diagnostic Value in Colorectal Cancer

  Philip D. Dunne;Darragh G. McArt;Conor A. Bradley;Paul G. O'Reilly

  163
  Citations

• Hypoxia in prostate cancer: a powerful shield against tumour destruction?

  L. Marignol;M. Coffey;M. Lawler;D. Hollywood

  154
  Citations

• The epigenome as a therapeutic target in prostate cancer

  Antoinette S Perry;R William G Watson;Mark Lawler;Donal Hollywood

  154
  Citations

• Autosomal dominant retinitis pigmentosa: linkage to rhodopsin and evidence for genetic heterogeneity

  G. Jane Farrar;Peter McWilliam;Daniel G. Bradley;Paul Kenna

  145
  Citations

• A harmonized meta-knowledgebase of clinical interpretations of somatic genomic variants in cancer.

  Alex H Wagner;Brian Walsh;Georgia Mayfield;David Tamborero;David Tamborero

  140
  Citations

• Personalized management of elderly patients with rectal cancer: Expert recommendations of the European Society of Surgical Oncology, European Society of Coloproctology, International Society of Geriatric Oncology, and American College of Surgeons Commission on Cancer

  Isacco Montroni;Giampaolo Ugolini;Nicole M. Saur;Antonino Spinelli

  135
  Citations

• Wilms' tumor gene 1 (WT1) expression in childhood acute lymphoblastic leukemia: a wide range of WT1 expression levels, its impact on prognosis and minimal residual disease monitoring

  L Boublikova;M Kalinova;J Ryan;F Quinn

  125
  Citations

• The emerging roles of DNA methylation in the clinical management of prostate cancer.

  Antoinette S Perry;Ruth Foley;Karen Woodson;Mark Lawler

  118
  Citations