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Genetics
Ireland
2026

D-Index & Metrics

Genetics

D-Index
66
Citations
14270
World Ranking
2629
National Ranking
10

Research.com Recognitions

  • 2026 - Research.com Genetics in Ireland Leader Award
  • 2025 - Research.com Genetics in Ireland Leader Award
  • 1996 - Member of the Royal Irish Academy

Overview

Peter Humphries is affiliated with Trinity College Dublin in Ireland and has contributed extensively to the fields of mathematics and molecular biology, with a particular focus on retinal development and disorders. Their work spans several subfields, including mathematical physics, algebra and number theory, geometry and topology, and applied mathematics.

This researcher has published in a variety of scientific venues, including:

  • arXiv (Cornell University)
  • The Medical Journal of Australia
  • Investigative Ophthalmology & Visual Science
  • Genes
  • Science Advances

Among their notable papers are:

  • Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms, 2022, Investigative Ophthalmology & Visual Science
  • Findings from a Genotyping Study of over 1000 People with Inherited Retinal Disorders in Ireland, 2020, Genes
  • Matrix metalloproteinase-3 (MMP-3)-mediated gene therapy for glaucoma, 2023, Science Advances
  • Optimized OPA1 Isoforms 1 and 7 Provide Therapeutic Benefit in Models of Mitochondrial Dysfunction, 2020, Frontiers in Neuroscience
  • Novel 199 base pair NEFH promoter drives expression in retinal ganglion cells, 2020, Scientific Reports

Their research covers topics such as:

  • Advanced Algebra and Geometry
  • Analytic Number Theory Research
  • Algebraic Geometry and Number Theory
  • Finite Group Theory Research
  • Retinal Development and Disorders
  • advanced mathematical theories
  • Glaucoma and retinal disorders

Frequent collaborators in their work include:

  • Jesse Thorner
  • Rizwanur Khan
  • Paul F. Kenna
  • G. Jane Farrar
  • Matthew Carrigan

Peter Humphries' awards include being named a Member of the Royal Irish Academy in 1996.

Best Publications

  • Genetic Reactivation of Cone Photoreceptors Restores Visual Responses in Retinitis Pigmentosa

    Volker Busskamp;Jens Duebel;David Balya;Mathias Fradot;Mathias Fradot;Mathias Fradot

  • Retinopathy induced in mice by targeted disruption of the rhodopsin gene

    Humphries Mm;Rancourt D;Farrar Gj;Kenna P;Kenna P

  • A three-base-pair deletion in the peripherin– RDS gene in one form of retinitis pigmentosa

    Farrar Gj;Kenna P;Jordan Sa;Kumar-Singh R

  • NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components

    Sarah L. Doyle;Matthew Campbell;Ema Ozaki;Robert G. Salomon

  • Autosomal dominant retinitis pigmentosa (ADRP): Localization of an ADRP gene to the long arm of chromosome 3

    Peter McWilliam;G.Jane Farrar;Paul Kenna;Daniel G. Bradley

  • On the genetics of retinitis pigmentosa and on mutation-independent approaches to therapeutic intervention

    G. Jane Farrar;Paul F. Kenna;Peter Humphries

  • The Blood-Retina Barrier

    Matthew Campbell;Peter Humphries

  • On the molecular genetics of retinitis pigmentosa

    P Humphries;P Kenna;GJ Farrar

  • New views on RPE65 deficiency: the rod system is the source of vision in a mouse model of Leber congenital amaurosis.

    Mathias W. Seeliger;Christian Grimm;Fredrik Ståhlberg;Fredrik Ståhlberg;Christoph Friedburg

  • Dose-dependent expression of claudin-5 is a modifying factor in schizophrenia

    C Greene;J Kealy;M M Humphries;Y Gong

  • Identification of an IMPDH1 mutation in autosomal dominant retinitis pigmentosa (RP10) revealed following comparative microarray analysis of transcripts derived from retinas of wild-type and Rho-/- mice.

    Avril Kennan;Aileen Aherne;Arpad Palfi;Marian Humphries

  • Evaluation of mixed chimerism by in vitro amplification of dinucleotide repeat sequences using the polymerase chain reaction

    M Lawler;P Humphries;SR McCann

  • RNA interference-mediated suppression and replacement of human rhodopsin in vivo.

    Mary O’Reilly;Arpad Palfi;Naomi Chadderton;Sophia Millington-Ward

  • Spectral Domain Optical Coherence Tomography in Mouse Models of Retinal Degeneration

    Gesine Huber;Susanne C. Beck;Christian Grimm;Ayse Sahaboglu-Tekgoz

  • Retinal cells integrate into the outer nuclear layer and differentiate into mature photoreceptors after subretinal transplantation into adult mice.

    Udo Bartsch;Wasi Oriyakhel;Paul F. Kenna;Stephan Linke

  • Cone opsin mislocalization in Rpe65-/- mice: a defect that can be corrected by 11-cis retinal.

    Baerbel Rohrer;Heather R. Lohr;Peter Humphries;T. Michael Redmond

  • Light in retinitis pigmentosa.

    Avril Kennan;Aileen Aherne;Pete Humphries

  • Altered retinal microRNA expression profile in a mouse model of retinitis pigmentosa.

    Carol J Loscher;Karsten Hokamp;Paul F Kenna;Alasdair C Ivens

  • Improved retinal function in a mouse model of dominant retinitis pigmentosa following AAV-delivered gene therapy.

    Naomi Chadderton;Sophia Millington-Ward;Arpad Palfi;Mary O'Reilly

  • Suppression and Replacement Gene Therapy for Autosomal Dominant Disease in a Murine Model of Dominant Retinitis Pigmentosa

    Sophia Millington-Ward;Naomi Chadderton;Mary O'Reilly;Arpad Palfi

Frequent Co-Authors

Paul F. Kenna
Paul F. Kenna Trinity College Dublin
G. Jane Farrar
G. Jane Farrar Trinity College Dublin
Mark Lawler
Mark Lawler Queen's University Belfast
Martin Biel
Martin Biel Ludwig-Maximilians-Universität München
Stephen P. Daiger
Stephen P. Daiger The University of Texas Health Science Center at Houston
Mathias W. Seeliger
Mathias W. Seeliger University of Tübingen
Uwe Wolfrum
Uwe Wolfrum Johannes Gutenberg University of Mainz
Andreas Wenzel
Andreas Wenzel Novartis (Switzerland)
Daniel G. Bradley
Daniel G. Bradley Trinity College Dublin
Andreas Gal
Andreas Gal Universität Hamburg

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