D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics D-index 64 Citations 12,400 282 World Ranking 2018 National Ranking 8

Research.com Recognitions

Awards & Achievements

1996 - Member of the Royal Irish Academy

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Genetics

Peter Humphries mainly investigates Retinitis pigmentosa, Genetics, Gene, Rhodopsin and Retinal. His research in Retinitis pigmentosa intersects with topics in Retinal degeneration, Night vision, Congenital stationary night blindness and Point mutation. His Rhodopsin study integrates concerns from other disciplines, such as Molecular biology, Mutant, Electroretinography and Novel mutation.

His Retinal research includes themes of Retinopathy, Retina and Cell biology. His research integrates issues of Biophysics, Homeostasis and Anatomy in his study of Retina. In his research, Transgene is intimately related to Opsin, which falls under the overarching field of Cell biology.

His most cited work include:

  • Genetic Reactivation of Cone Photoreceptors Restores Visual Responses in Retinitis Pigmentosa (471 citations)
  • Retinopathy induced in mice by targeted disruption of the rhodopsin gene (470 citations)
  • A three-base-pair deletion in the peripherin– RDS gene in one form of retinitis pigmentosa (354 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Genetics, Retinitis pigmentosa, Gene, Cell biology and Molecular biology. In his work, Mutant, Genetically modified mouse and Transgene is strongly intertwined with Rhodopsin, which is a subfield of Retinitis pigmentosa. His Gene course of study focuses on Nucleic acid and Effector.

The various areas that Peter Humphries examines in his Cell biology study include Retina, Retinal, Knockout mouse and Gene expression. His Retinal research includes themes of Macular degeneration and Pathology. His biological study deals with issues like DNA, which deal with fields such as Recombinant DNA.

He most often published in these fields:

  • Genetics (40.46%)
  • Retinitis pigmentosa (33.88%)
  • Gene (28.95%)

What were the highlights of his more recent work (between 2011-2021)?

  • Retina (17.43%)
  • Retinal (16.12%)
  • Cell biology (19.41%)

In recent papers he was focusing on the following fields of study:

Peter Humphries spends much of his time researching Retina, Retinal, Cell biology, Retinal degeneration and Retinitis pigmentosa. The Retina study combines topics in areas such as Genetic enhancement and Pathology. The study incorporates disciplines such as Cell type and Bioinformatics in addition to Retinal.

His studies in Cell biology integrate themes in fields like Programmed cell death, Transgene and Blood-retina barrier. Peter Humphries interconnects Degeneration, Rhodopsin and Knockout mouse in the investigation of issues within Retinal degeneration. His Retinitis pigmentosa study deals with the bigger picture of Genetics.

Between 2011 and 2021, his most popular works were:

  • NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components (280 citations)
  • The Blood-Retina Barrier (114 citations)
  • IL-18 attenuates experimental choroidal neovascularization as a potential therapy for wet age-related macular degeneration. (75 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Mutation

Peter Humphries mainly focuses on Genetics, Retinitis pigmentosa, Retina, Tight junction and Retinal. His research in Retinal degeneration, Mutation and Gene are components of Genetics. His Retinitis pigmentosa study incorporates themes from Disease and DNA sequencing.

His Retina study combines topics in areas such as Transgene, Recombinant DNA, Real-time polymerase chain reaction, Green fluorescent protein and Flow cytometry. His work deals with themes such as Cognition, Homeostasis and Small interfering RNA, which intersect with Tight junction. His Retinal study combines topics from a wide range of disciplines, such as Inflammasome, Notch signaling pathway and Transplantation.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Genetic Reactivation of Cone Photoreceptors Restores Visual Responses in Retinitis Pigmentosa

Volker Busskamp;Jens Duebel;David Balya;Mathias Fradot;Mathias Fradot;Mathias Fradot.
Science (2010)

679 Citations

Retinopathy induced in mice by targeted disruption of the rhodopsin gene

Humphries Mm;Rancourt D;Farrar Gj;Kenna P;Kenna P.
Nature Genetics (1997)

611 Citations

A three-base-pair deletion in the peripherin– RDS gene in one form of retinitis pigmentosa

Farrar Gj;Kenna P;Jordan Sa;Kumar-Singh R.
Nature (1991)

500 Citations

NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components

Sarah L. Doyle;Matthew Campbell;Ema Ozaki;Robert G. Salomon.
Nature Medicine (2012)

401 Citations

Autosomal dominant retinitis pigmentosa (ADRP): Localization of an ADRP gene to the long arm of chromosome 3

Peter McWilliam;G.Jane Farrar;Paul Kenna;Daniel G. Bradley.
Genomics (1989)

305 Citations

On the genetics of retinitis pigmentosa and on mutation-independent approaches to therapeutic intervention

G. Jane Farrar;Paul F. Kenna;Peter Humphries.
The EMBO Journal (2002)

292 Citations

On the molecular genetics of retinitis pigmentosa

P Humphries;P Kenna;GJ Farrar.
Science (1992)

258 Citations

New views on RPE65 deficiency: the rod system is the source of vision in a mouse model of Leber congenital amaurosis.

Mathias W. Seeliger;Christian Grimm;Fredrik Ståhlberg;Fredrik Ståhlberg;Christoph Friedburg.
Nature Genetics (2001)

257 Citations

The Blood-Retina Barrier

Matthew Campbell;Peter Humphries.
Advances in Experimental Medicine and Biology (2013)

224 Citations

Evaluation of mixed chimerism by in vitro amplification of dinucleotide repeat sequences using the polymerase chain reaction

M Lawler;P Humphries;SR McCann.
Blood (1991)

222 Citations

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