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Mathias W. Seeliger

Mathias W. Seeliger

D-Index & Metrics

Biology and Biochemistry

D-Index
72
Citations
16306
World Ranking
6391
National Ranking
449

Overview

Mathias W. Seeliger is affiliated with the University of Tübingen in Germany. Their research spans multiple fields with a focus on biochemistry, genetics, molecular biology, medicine, and neuroscience.

The main subfields of study in their work include:

  • Molecular Biology
  • Ophthalmology
  • Cellular and Molecular Neuroscience
  • Neurology
  • Radiology, Nuclear Medicine and Imaging

Seeliger's primary research topics cover a range of areas related to vision and retinal conditions:

  • Retinal Development and Disorders
  • Retinal Diseases and Treatments
  • Connexins and lens biology
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Photoreceptor and optogenetics research
  • Retinal and Optic Conditions
  • Cell Adhesion Molecules Research

Recent significant papers authored or co-authored by Seeliger include:

  • "Safety and Vision Outcomes of Subretinal Gene Therapy Targeting Cone Photoreceptors in Achromatopsia," 2020, JAMA Ophthalmology
  • "Three-year results of phase I retinal gene therapy trial for CNGA3-mutated achromatopsia: results of a non randomised controlled trial," 2021, British Journal of Ophthalmology
  • "Mural Cell SRF Controls Pericyte Migration, Vessel Patterning and Blood Flow," 2022, Circulation Research
  • "Inherited Retinal Degeneration: PARP-Dependent Activation of Calpain Requires CNG Channel Activity," 2022, Biomolecules
  • "T-type voltage-gated channels, Na+/Ca2+-exchanger, and calpain-2 promote photoreceptor cell death in inherited retinal degeneration," 2024, Cell Communication and Signaling

Frequent co-authors in their publications include:

  • Regine Mühlfriedel
  • François Paquet-Durand
  • Alexander Günter
  • Vithiyanjali Sothilingam
  • Regine Muehlfriedel

Seeliger has published regularly in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • British Journal of Ophthalmology
  • JAMA Ophthalmology
  • Circulation Research
  • Biomolecules

Best Publications

  • Genetic Reactivation of Cone Photoreceptors Restores Visual Responses in Retinitis Pigmentosa

    Volker Busskamp;Jens Duebel;David Balya;Mathias Fradot;Mathias Fradot;Mathias Fradot

  • HIF-1-induced erythropoietin in the hypoxic retina protects against light-induced retinal degeneration

    Christian Grimm;Andreas Wenzel;Matthias Groszer;Helmut Mayser

  • Mutation of CDH23, encoding a new member of the cadherin gene family, causes Usher syndrome type 1D

    Bolz H;von Brederlow B;Ramírez A;Bryda Ec

  • Genetic disorders of vision revealed by a behavioral screen of 400 essential loci in zebrafish.

    Stephan C. F. Neuhauss;Oliver Biehlmaier;Mathias W. Seeliger;Tilak Das

  • Selective loss of cone function in mice lacking the cyclic nucleotide-gated channel CNG3

    Martin Biel;Mathias Seeliger;Alexander Pfeifer;Konrad Kohler

  • Guidelines for basic multifocal electroretinography (mfERG)

    Michael F Marmor;Donald C Hood;David Keating;Mineo Kondo

  • Disruption of the taurine transporter gene (taut) leads to retinal degeneration in mice

    Birgit Heller-Stilb;Claudia van Roeyen;Kristina Rascher;Hans-Georg Hartwig

  • Functional and structural recovery of the retina after gene therapy in the RPE65 null mutation dog.

    Kristina Narfström;Martin L Katz;Ragnheidur Bragadottir;Mathias Seeliger

  • Crumbs homologue 1 is required for maintenance of photoreceptor cell polarization and adhesion during light exposure.

    Serge A. van de Pavert;Albena Kantardzhieva;Anna Malysheva;Jan Meuleman

  • Detection of behavioral alterations and learning deficits in mice lacking synaptophysin.

    U. Schmitt;N. Tanimoto;M. Seeliger;F. Schaeffel

  • New views on RPE65 deficiency: the rod system is the source of vision in a mouse model of Leber congenital amaurosis.

    Mathias W. Seeliger;Christian Grimm;Fredrik Ståhlberg;Fredrik Ståhlberg;Christoph Friedburg

  • Noninvasive, In Vivo Assessment of Mouse Retinal Structure Using Optical Coherence Tomography

    M. Dominik Fischer;Gesine Huber;Gesine Huber;Susanne C. Beck;Naoyuki Tanimoto

  • Prolonged Recovery of Retinal Structure/Function after Gene Therapy in an Rs1h-Deficient Mouse Model of X-Linked Juvenile Retinoschisis

    Seok H. Min;Laurie L. Molday;Mathias W. Seeliger;Astra Dinculescu

  • Inactivation of the murine X-linked juvenile retinoschisis gene, Rs1h, suggests a role of retinoschisin in retinal cell layer organization and synaptic structure.

    Bernhard H. F. Weber;Heinrich Schrewe;Laurie L. Molday;Andrea Gehrig

  • A portable albumin binder from a DNA-encoded chemical library

    Christoph E. Dumelin;Sabrina Trüssel;Fabian Buller;Eveline Trachsel

  • Mutations in the unfolded protein response regulator ATF6 cause the cone dysfunction disorder achromatopsia

    Susanne Kohl;Ditta Zobor;Wei-Chieh Chiang;Nicole Weisschuh

  • Spectral Domain Optical Coherence Tomography in Mouse Models of Retinal Degeneration

    Gesine Huber;Susanne C. Beck;Christian Grimm;Ayse Sahaboglu-Tekgoz

  • Restoration of Cone Vision in the CNGA3−/− Mouse Model of Congenital Complete Lack of Cone Photoreceptor Function

    Stylianos Michalakis;Regine Mühlfriedel;Naoyuki Tanimoto;Vidhyasankar Krishnamoorthy

  • Loss of the Cholesterol-Binding Protein Prominin-1/CD133 Causes Disk Dysmorphogenesis and Photoreceptor Degeneration

    Serena Zacchigna;Hideyasu Oh;Michaela Wilsch-Bräuninger;Ewa Missol-Kolka

  • In vivo confocal imaging of the retina in animal models using scanning laser ophthalmoscopy

    Mathias W. Seeliger;Susanne C. Beck;Naira Pereyra-Muñoz;Susann Dangel

Frequent Co-Authors

Martin Biel
Martin Biel Ludwig-Maximilians-Universität München
Eberhart Zrenner
Eberhart Zrenner University of Tübingen
Jan Wijnholds
Jan Wijnholds Leiden University Medical Center
Christian Grimm
Christian Grimm University of Zurich
Bernd Wissinger
Bernd Wissinger University of Tübingen
Andreas Wenzel
Andreas Wenzel Novartis (Switzerland)
Peter Humphries
Peter Humphries Trinity College Dublin
Bernhard H. F. Weber
Bernhard H. F. Weber University of Regensburg
Susanne Kohl
Susanne Kohl University of Tübingen
Charlotte E. Remé
Charlotte E. Remé University of Zurich

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