D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 53 Citations 9,861 131 World Ranking 8553 National Ranking 152

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Retina

Christian Grimm spends much of his time researching Retinal degeneration, Retina, Cell biology, Retinal and Apoptosis. His Retinal degeneration research incorporates elements of Photoreceptor cell and Retinal pigment epithelium, RPE65. His work deals with themes such as Erythropoietin, Hypoxia and Vascular endothelial growth factor, which intersect with Retina.

His study in Cell biology is interdisciplinary in nature, drawing from both Genetics, Retinitis pigmentosa, Programmed cell death and Small nuclear RNA. His biological study spans a wide range of topics, including Phagocyte, Neuroglia, Anatomy and Pathology. The Apoptosis study combines topics in areas such as Gene expression, Transcription factor, Immunology, Molecular biology and Knockout mouse.

His most cited work include:

  • Molecular mechanisms of light-induced photoreceptor apoptosis and neuroprotection for retinal degeneration. (533 citations)
  • HIF-1-induced erythropoietin in the hypoxic retina protects against light-induced retinal degeneration (467 citations)
  • Genetic engineering of Schizosaccharomyces pombe: a system for gene disruption and replacement using the ura4 gene as a selectable marker. (361 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Cell biology, Retina, Retinal, Retinal degeneration and Apoptosis. His Cell biology research is multidisciplinary, incorporating perspectives in Neuroprotection, Hypoxia, Programmed cell death and Transcription factor. His Retina research focuses on subjects like Molecular biology, which are linked to RNA.

His Retinal study integrates concerns from other disciplines, such as Macular degeneration, Anatomy and Pathology. Mutant is closely connected to RPE65 in his research, which is encompassed under the umbrella topic of Retinal degeneration. Christian Grimm interconnects Erythropoietin, Immunology and c-Fos in the investigation of issues within Apoptosis.

He most often published in these fields:

  • Cell biology (46.41%)
  • Retina (39.24%)
  • Retinal (38.40%)

What were the highlights of his more recent work (between 2017-2021)?

  • Retinal (38.40%)
  • Cell biology (46.41%)
  • Retina (39.24%)

In recent papers he was focusing on the following fields of study:

Christian Grimm mainly focuses on Retinal, Cell biology, Retina, Retinal degeneration and Retinal pigment epithelium. His Retinal research is multidisciplinary, relying on both Biophysics, Hypoxia, Macular degeneration and Pathology. His work deals with themes such as Autophagy, Methylation, Zebrafish, Opsin and Visual phototransduction, which intersect with Cell biology.

His studies deal with areas such as Rhodopsin, Neurodegeneration and Neuroprotection as well as Retina. His research integrates issues of Light damage, Molecular biology, Hot spot and Programmed cell death in his study of Retinal degeneration. The Retinal pigment epithelium study combines topics in areas such as PEDF and Outer nuclear layer.

Between 2017 and 2021, his most popular works were:

  • Impaired ABCA1/ABCG1-mediated lipid efflux in the mouse retinal pigment epithelium (RPE) leads to retinal degeneration (26 citations)
  • OCRL deficiency impairs endolysosomal function in a humanized mouse model for Lowe syndrome and Dent disease. (19 citations)
  • Hif1a inactivation rescues photoreceptor degeneration induced by a chronic hypoxia-like stress (16 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Internal medicine

His primary areas of study are Retinal, Retina, Macular degeneration, Retinal degeneration and Pathology. Christian Grimm has included themes like Biomarker, Molecular biology and Proteomics in his Retinal study. Retinal pigment epithelium is the focus of his Retina research.

His studies in Retinal degeneration integrate themes in fields like Outer plexiform layer, Neurodegeneration and Cell biology. Christian Grimm combines subjects such as Rhodopsin, Lipid metabolism, Genetically modified mouse and Neuroprotection with his study of Cell biology. His biological study spans a wide range of topics, including Multiple sclerosis, Optic neuritis and Optic nerve.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Molecular mechanisms of light-induced photoreceptor apoptosis and neuroprotection for retinal degeneration.

Andreas Wenzel;Christian Grimm;Marijana Samardzija;Charlotte E. Remé.
Progress in Retinal and Eye Research (2005)

842 Citations

HIF-1-induced erythropoietin in the hypoxic retina protects against light-induced retinal degeneration

Christian Grimm;Andreas Wenzel;Matthias Groszer;Helmut Mayser.
Nature Medicine (2002)

727 Citations

Genetic engineering of Schizosaccharomyces pombe: a system for gene disruption and replacement using the ura4 gene as a selectable marker.

Christian Grimm;Jürg Kohli;Johanne Murray;Kinsey Maundrell.
Molecular Genetics and Genomics (1988)

563 Citations

Age-related macular degeneration. The lipofusion component N-retinyl-N-retinylidene ethanolamine detaches proapoptotic proteins from mitochondria and induces apoptosis in mammalian retinal pigment epithelial cells.

Marianne Suter;Charlotte E. Reme;Christian Grimm;Andreas Wenzel.
Journal of Biological Chemistry (2000)

449 Citations

Protection of Rpe65 -deficient mice identifies rhodopsin as a mediator of light-induced retinal degeneration

C Grimm;A Wenzel;F Hafezi;S Yu.
Nature Genetics (2000)

319 Citations

Evidence for two apoptotic pathways in light-induced retinal degeneration

Wenshan Hao;Wenshan Hao;Andreas Wenzel;Martin S. Obin;Ching-Kang Chen;Ching-Kang Chen.
Nature Genetics (2002)

318 Citations

The Rpe65 Leu450Met Variation Increases Retinal Resistance Against Light-Induced Degeneration by Slowing Rhodopsin Regeneration

Andreas Wenzel;Charlotte E. Remé;Theodore P. Williams;Farhad Hafezi.
The Journal of Neuroscience (2001)

303 Citations

Apoptotic cell death in retinal degenerations.

Charlotte E Remé;Christian Grimm;Farhad Hafezi;Andreas Marti.
Progress in Retinal and Eye Research (1998)

281 Citations

Rhodopsin-mediated blue-light damage to the rat retina: effect of photoreversal of bleaching.

Christian Grimm;Andreas Wenzel;Theodore P. Williams;Pascal O. Rol.
Investigative Ophthalmology & Visual Science (2001)

274 Citations

The constitutive transport element (CTE) of Mason-Pfizer monkey virus (MPMV) accesses a cellular mRNA export pathway.

Amy E. Pasquinelli;Robert K. Ernst;Elsebet Lund;Christian Grimm.
The EMBO Journal (1997)

274 Citations

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