2026 Christian Grimm: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	63	10301	9512	184	162	245	13002

Overview

Christian Grimm is affiliated with the University of Zurich in Switzerland. Their research work spans multiple areas within biochemistry, genetics, molecular biology, and medicine, with a focus on molecular biology and ophthalmology.

The scientist's main fields of study include:

Biochemistry, Genetics and Molecular Biology
Medicine

Subfields of interest are diverse and cover:

Molecular Biology
Ophthalmology
Cancer Research
Cellular and Molecular Neuroscience
Genetics

The topics addressed in their research include:

Retinal Development and Disorders
Retinal Diseases and Treatments
Photoreceptor and optogenetics research
Cancer, Hypoxia, and Metabolism
Interferon and immune responses
Virus-based gene therapy research
Circadian rhythm and melatonin

Christian Grimm has published several papers, notable recent works include:

mRNA trans-splicing dual AAV vectors for (epi)genome editing and gene therapy, 2023, Nature Communications
HDAC inhibition ameliorates cone survival in retinitis pigmentosa mice, 2020, Cell Death and Differentiation
Single-cell RNA sequencing of the retina in a model of retinitis pigmentosa reveals early responses to degeneration in rods and cones, 2022, BMC Biology
Retinal Layer Separation (ReLayS) method enables the molecular analysis of photoreceptor segments and cell bodies, as well as the inner retina, 2022, Scientific Reports
Deficits in mitochondrial TCA cycle and OXPHOS precede rod photoreceptor degeneration during chronic HIF activation, 2023, Molecular Neurodegeneration

Frequent co-authors collaborating with Christian Grimm are:

Marijana Samardzija
Duygu Karademir
Lynn J. A. Ebner
Luca Merolla
Vyara Todorova

The researcher has contributed to publications in venues including:

Advances in Experimental Medicine and Biology
Experimental Eye Research
bioRxiv (Cold Spring Harbor Laboratory)
Scientific Reports
Nature Communications

Best Publications

Molecular mechanisms of light-induced photoreceptor apoptosis and neuroprotection for retinal degeneration.

Andreas Wenzel;Christian Grimm;Marijana Samardzija;Charlotte E. Remé

895
Citations
HIF-1-induced erythropoietin in the hypoxic retina protects against light-induced retinal degeneration

Christian Grimm;Andreas Wenzel;Matthias Groszer;Helmut Mayser

752
Citations
Genetic engineering of Schizosaccharomyces pombe: a system for gene disruption and replacement using the ura4 gene as a selectable marker.

Christian Grimm;Jürg Kohli;Johanne Murray;Kinsey Maundrell

594
Citations
Age-related macular degeneration. The lipofusion component N-retinyl-N-retinylidene ethanolamine detaches proapoptotic proteins from mitochondria and induces apoptosis in mammalian retinal pigment epithelial cells.

Marianne Suter;Charlotte E. Reme;Christian Grimm;Andreas Wenzel

465
Citations
Protection of Rpe65 -deficient mice identifies rhodopsin as a mediator of light-induced retinal degeneration

C Grimm;A Wenzel;F Hafezi;S Yu

355
Citations
Evidence for two apoptotic pathways in light-induced retinal degeneration

Wenshan Hao;Andreas Wenzel;Martin S. Obin;Ching-Kang Chen;Ching-Kang Chen

345
Citations
The Rpe65 Leu450Met Variation Increases Retinal Resistance Against Light-Induced Degeneration by Slowing Rhodopsin Regeneration

Andreas Wenzel;Charlotte E. Remé;Theodore P. Williams;Farhad Hafezi

334
Citations
Rhodopsin-mediated blue-light damage to the rat retina: effect of photoreversal of bleaching.

Christian Grimm;Andreas Wenzel;Theodore P. Williams;Pascal O. Rol

324
Citations
The constitutive transport element (CTE) of Mason-Pfizer monkey virus (MPMV) accesses a cellular mRNA export pathway.

Amy E. Pasquinelli;Robert K. Ernst;Elsebet Lund;Christian Grimm

305
Citations
Apoptotic cell death in retinal degenerations.

Charlotte E Remé;Christian Grimm;Farhad Hafezi;Andreas Marti

295
Citations
New views on RPE65 deficiency: the rod system is the source of vision in a mouse model of Leber congenital amaurosis.

Mathias W. Seeliger;Christian Grimm;Fredrik Ståhlberg;Fredrik Ståhlberg;Christoph Friedburg

258
Citations
Noninvasive, In Vivo Assessment of Mouse Retinal Structure Using Optical Coherence Tomography

M. Dominik Fischer;Gesine Huber;Gesine Huber;Susanne C. Beck;Naoyuki Tanimoto

243
Citations
Spectral Domain Optical Coherence Tomography in Mouse Models of Retinal Degeneration

Gesine Huber;Susanne C. Beck;Christian Grimm;Ayse Sahaboglu-Tekgoz

215
Citations
c-fos Controls the “Private Pathway” of Light-Induced Apoptosis of Retinal Photoreceptors

Andreas Wenzel;Christian Grimm;Andreas Marti;Nicole Kueng-Hitz

204
Citations
From oxygen to erythropoietin: relevance of hypoxia for retinal development, health and disease.

Christian Caprara;Christian Grimm

190
Citations
Gene expression in the mouse retina: the effect of damaging light.

Grimm C;Wenzel A;Hafezi F;Remé Ce

185
Citations
Cooperative Phagocytes: Resident Microglia and Bone Marrow Immigrants Remove Dead Photoreceptors in Retinal Lesions

Sandrine Joly;Mike Francke;Elke Ulbricht;Susanne Beck

184
Citations
Role of the Norrie disease pseudoglioma gene in sprouting angiogenesis during development of the retinal vasculature.

Ulrich F O Luhmann;Jihong Lin;Niyazi Acar;Stefanie Lammel

173
Citations
Differential role of Jak-STAT signaling in retinal degenerations

Marijana Samardzija;Andreas Wenzel;Svenja Aufenberg;Markus Thiersch

166
Citations
Leukemia Inhibitory Factor Extends the Lifespan of Injured Photoreceptors In Vivo

Sandrine Joly;Christina Lange;Markus Thiersch;Marijana Samardzija

163
Citations