D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 132 Citations 56,521 689 World Ranking 265 National Ranking 191

Research.com Recognitions

Awards & Achievements

2019 - Member of the National Academy of Medicine (NAM)

2012 - Prize of the Foundation for Polish Science - Nagroda Fundacji na rzecz Nauki Polskiej for characterizing crystal structures of native and activated G protein-coupled receptor, rhodopsin, involved in eyesight

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Biochemistry

Krzysztof Palczewski mostly deals with Biochemistry, Rhodopsin, Visual phototransduction, Retinal and Cell biology. As part of his studies on Biochemistry, he often connects relevant subjects like Biophysics. His research in Rhodopsin intersects with topics in Protein structure, G protein-coupled receptor, Rhodopsin kinase and Phosphorylation.

The Visual phototransduction study combines topics in areas such as Arrestin, GUCY2D, Crystallography, Regeneration and Retinal Cone Photoreceptor Cells. His work in Retinal covers topics such as Retina which are related to areas like Binding protein, Molecular biology, Endocrinology and Anatomy. His biological study spans a wide range of topics, including Mutation and Calcium-binding protein.

His most cited work include:

  • Crystal Structure of Rhodopsin: A G Protein-Coupled Receptor (4772 citations)
  • Atomic-force microscopy: Rhodopsin dimers in native disc membranes (663 citations)
  • G protein-coupled receptor rhodopsin. (548 citations)

What are the main themes of his work throughout his whole career to date?

Krzysztof Palczewski mainly focuses on Biochemistry, Rhodopsin, Cell biology, Visual phototransduction and Retinal. His Rhodopsin research is multidisciplinary, incorporating perspectives in Biophysics, G protein-coupled receptor and Rhodopsin kinase. His studies in G protein-coupled receptor integrate themes in fields like Heterotrimeric G protein, G protein, Membrane protein and Transmembrane protein.

His work deals with themes such as Photoreceptor cell, Genetics and Calcium-binding protein, which intersect with Cell biology. His research in Visual phototransduction intersects with topics in Retinal Cone Photoreceptor Cells and Retinaldehyde. Krzysztof Palczewski interconnects Retina and Internal medicine in the investigation of issues within Retinal.

He most often published in these fields:

  • Biochemistry (34.97%)
  • Rhodopsin (32.31%)
  • Cell biology (27.83%)

What were the highlights of his more recent work (between 2015-2021)?

  • Retinal (22.66%)
  • Cell biology (27.83%)
  • Retina (20.28%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Retinal, Cell biology, Retina, Visual phototransduction and Biophysics. His Retinal research entails a greater understanding of Biochemistry. The study incorporates disciplines such as Retinal degeneration and Retinitis pigmentosa in addition to Cell biology.

His Visual phototransduction research includes elements of Adaptation, Electroretinography, Regeneration and Retinaldehyde. His Biophysics research is multidisciplinary, relying on both G protein-coupled receptor, Chromophore, Rhodopsin, Opsin and Phosphodiesterase. His Rhodopsin study combines topics from a wide range of disciplines, such as Protein structure, Membrane protein and Function.

Between 2015 and 2021, his most popular works were:

  • Retinoids and Retinal Diseases. (47 citations)
  • Two-Photon Autofluorescence Imaging Reveals Cellular Structures Throughout the Retina of the Living Primate Eye (45 citations)
  • Photoreceptor Cells Influence Retinal Vascular Degeneration in Mouse Models of Retinal Degeneration and Diabetes. (37 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Amino acid

His scientific interests lie mostly in Cell biology, G protein-coupled receptor, Rhodopsin, Retinal and Retina. His Cell biology research incorporates themes from Retinal degeneration and Retinitis pigmentosa. The G protein-coupled receptor study combines topics in areas such as Helix and Stereochemistry.

As part of his studies on Rhodopsin, he frequently links adjacent subjects like Biophysics. His Retinal research includes themes of Endocrinology, Internal medicine, Vascular permeability and Gene, Transfection. His Retina research integrates issues from Genetics, Autofluorescence and Computational biology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Crystal Structure of Rhodopsin: A G Protein-Coupled Receptor

Krzysztof Palczewski;T. Kumasaka;T. Hori;C. A. Behnke.
Science (2000)

7108 Citations

Advances in determination of a high-resolution three-dimensional structure of rhodopsin, a model of G-protein-coupled receptors (GPCRs).

David C. Teller;Tetsuji Okada;Craig A. Behnke;Krzysztof Palczewski.
Biochemistry (2001)

812 Citations

Atomic-force microscopy: Rhodopsin dimers in native disc membranes

Dimitrios Fotiadis;Yan Liang;Slawomir Filipek;David A Saperstein.
Nature (2003)

803 Citations

G protein-coupled receptor rhodopsin.

Krzysztof Palczewski.
Annual Review of Biochemistry (2006)

706 Citations

Organization of the G Protein-coupled Receptors Rhodopsin and Opsin in Native Membranes

Yan Liang;Dimitrios Fotiadis;Sławomir Filipek;David A. Saperstein.
Journal of Biological Chemistry (2003)

691 Citations

Long-Term Restoration of Rod and Cone Vision by Single Dose rAAV-Mediated Gene Transfer to the Retina in a Canine Model of Childhood Blindness

Gregory M. Acland;Gustavo D. Aguirre;Jean Bennett;Tomas S. Aleman.
Molecular Therapy (2005)

542 Citations

Crystal structure of a photoactivated deprotonated intermediate of rhodopsin.

David Salom;David T. Lodowski;Ronald E. Stenkamp;Isolde Le Trong.
Proceedings of the National Academy of Sciences of the United States of America (2006)

517 Citations

Activation of rhodopsin: new insights from structural and biochemical studies

Tetsuji Okada;Tetsuji Okada;Oliver P. Ernst;Krzysztof Palczewski;Klaus Peter Hofmann.
Trends in Biochemical Sciences (2001)

502 Citations

Sequence analyses of G-protein-coupled receptors: similarities to rhodopsin.

Tara Mirzadegan;Gil Benkö;Sławomir Filipek;Krzysztof Palczewski.
Biochemistry (2003)

467 Citations

Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agents.

Gabriel H. Travis;Marcin Golczak;Alexander R. Moise;Krzysztof Palczewski.
Annual Review of Pharmacology and Toxicology (2007)

438 Citations

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