2019 - Member of the National Academy of Medicine (NAM)
2012 - Prize of the Foundation for Polish Science - Nagroda Fundacji na rzecz Nauki Polskiej for characterizing crystal structures of native and activated G protein-coupled receptor, rhodopsin, involved in eyesight
Krzysztof Palczewski mostly deals with Biochemistry, Rhodopsin, Visual phototransduction, Retinal and Cell biology. As part of his studies on Biochemistry, he often connects relevant subjects like Biophysics. His research in Rhodopsin intersects with topics in Protein structure, G protein-coupled receptor, Rhodopsin kinase and Phosphorylation.
The Visual phototransduction study combines topics in areas such as Arrestin, GUCY2D, Crystallography, Regeneration and Retinal Cone Photoreceptor Cells. His work in Retinal covers topics such as Retina which are related to areas like Binding protein, Molecular biology, Endocrinology and Anatomy. His biological study spans a wide range of topics, including Mutation and Calcium-binding protein.
Krzysztof Palczewski mainly focuses on Biochemistry, Rhodopsin, Cell biology, Visual phototransduction and Retinal. His Rhodopsin research is multidisciplinary, incorporating perspectives in Biophysics, G protein-coupled receptor and Rhodopsin kinase. His studies in G protein-coupled receptor integrate themes in fields like Heterotrimeric G protein, G protein, Membrane protein and Transmembrane protein.
His work deals with themes such as Photoreceptor cell, Genetics and Calcium-binding protein, which intersect with Cell biology. His research in Visual phototransduction intersects with topics in Retinal Cone Photoreceptor Cells and Retinaldehyde. Krzysztof Palczewski interconnects Retina and Internal medicine in the investigation of issues within Retinal.
His primary scientific interests are in Retinal, Cell biology, Retina, Visual phototransduction and Biophysics. His Retinal research entails a greater understanding of Biochemistry. The study incorporates disciplines such as Retinal degeneration and Retinitis pigmentosa in addition to Cell biology.
His Visual phototransduction research includes elements of Adaptation, Electroretinography, Regeneration and Retinaldehyde. His Biophysics research is multidisciplinary, relying on both G protein-coupled receptor, Chromophore, Rhodopsin, Opsin and Phosphodiesterase. His Rhodopsin study combines topics from a wide range of disciplines, such as Protein structure, Membrane protein and Function.
His scientific interests lie mostly in Cell biology, G protein-coupled receptor, Rhodopsin, Retinal and Retina. His Cell biology research incorporates themes from Retinal degeneration and Retinitis pigmentosa. The G protein-coupled receptor study combines topics in areas such as Helix and Stereochemistry.
As part of his studies on Rhodopsin, he frequently links adjacent subjects like Biophysics. His Retinal research includes themes of Endocrinology, Internal medicine, Vascular permeability and Gene, Transfection. His Retina research integrates issues from Genetics, Autofluorescence and Computational biology.
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Crystal Structure of Rhodopsin: A G Protein-Coupled Receptor
Krzysztof Palczewski;T. Kumasaka;T. Hori;C. A. Behnke.
Advances in determination of a high-resolution three-dimensional structure of rhodopsin, a model of G-protein-coupled receptors (GPCRs).
David C. Teller;Tetsuji Okada;Craig A. Behnke;Krzysztof Palczewski.
Atomic-force microscopy: Rhodopsin dimers in native disc membranes
Dimitrios Fotiadis;Yan Liang;Slawomir Filipek;David A Saperstein.
G protein-coupled receptor rhodopsin.
Annual Review of Biochemistry (2006)
Organization of the G Protein-coupled Receptors Rhodopsin and Opsin in Native Membranes
Yan Liang;Dimitrios Fotiadis;Sławomir Filipek;David A. Saperstein.
Journal of Biological Chemistry (2003)
Long-Term Restoration of Rod and Cone Vision by Single Dose rAAV-Mediated Gene Transfer to the Retina in a Canine Model of Childhood Blindness
Gregory M. Acland;Gustavo D. Aguirre;Jean Bennett;Tomas S. Aleman.
Molecular Therapy (2005)
Crystal structure of a photoactivated deprotonated intermediate of rhodopsin.
David Salom;David T. Lodowski;Ronald E. Stenkamp;Isolde Le Trong.
Proceedings of the National Academy of Sciences of the United States of America (2006)
Activation of rhodopsin: new insights from structural and biochemical studies
Tetsuji Okada;Tetsuji Okada;Oliver P. Ernst;Krzysztof Palczewski;Klaus Peter Hofmann.
Trends in Biochemical Sciences (2001)
Sequence analyses of G-protein-coupled receptors: similarities to rhodopsin.
Tara Mirzadegan;Gil Benkö;Sławomir Filipek;Krzysztof Palczewski.
Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agents.
Gabriel H. Travis;Marcin Golczak;Alexander R. Moise;Krzysztof Palczewski.
Annual Review of Pharmacology and Toxicology (2007)
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