Alexander M. Dizhoor

Overview

Best Publications

• Ectopic Expression of a Microbial-Type Rhodopsin Restores Visual Responses in Mice with Photoreceptor Degeneration

  Anding Bi;Jinjuan Cui;Yu Ping Ma;Elena Olshevskaya

  941
  Citations

• Recoverin: a calcium sensitive activator of retinal rod guanylate cyclase.

  Alexander M. Dizhoor;Sanghamitra Ray;Santosh Kumar;Greg Niemi

  631
  Citations

• The human photoreceptor membrane guanylyl cyclase, RetGC, is present in outer segments and is regulated by calcium and a soluble activator

  Alexander M. Dizhoor;David G. Lowe;Elena V. Olshevskaya;Richard P. Laura

  486
  Citations

• Cloning, Sequencing, and Expression of a 24-kDa Ca2+-binding Protein Activating Photoreceptor Guanylyl Cyclase

  Alexander M. Dizhoor;Elena V. Olshevskaya;William J. Henzel;Susan C. Wong

  445
  Citations

• Recoverin immunoreactivity in mammalian cone bipolar cells.

  Ann H. Milam;Dennis M. Dacey;Alexander M. Dizhoor

  343
  Citations

• Cloning and expression of a second photoreceptor-specific membrane retina guanylyl cyclase (RetGC), RetGC-2

  David G. Lowe;Alexander M. Dizhoor;Kathleen Liu;Qimin Gu

  336
  Citations

• Role of the Acylated Amino Terminus of Recoverin in Ca 2+ -Dependent Membrane Interaction

  Alexander M. Dizhoor;Ching Kang Chen;Elena Olshevskaya;Valeria V. Sinelnikova

  303
  Citations

• Role of guanylate cyclase-activating proteins (GCAPs) in setting the flash sensitivity of rod photoreceptors.

  Ana Mendez;Marie E. Burns;Izabela Sokal;Alexander M. Dizhoor

  285
  Citations

• The NH2 terminus of retinal recoverin is acylated by a small family of fatty acids.

  Alexander M. Dizhoor;Lowell H. Ericsson;Richard S. Johnson;Santosh Kumar

  245
  Citations

• Constitutive Activation of Photoreceptor Guanylate Cyclase by Y99C Mutant of GCAP-1 POSSIBLE ROLE IN CAUSING HUMAN AUTOSOMAL DOMINANT CONE DEGENERATION

  Alexander M. Dizhoor;Sergei G. Boikov;Elena V. Olshevskaya

  218
  Citations

• Three-dimensional Structure of Guanylyl Cyclase Activating Protein-2, a Calcium-sensitive Modulator of Photoreceptor Guanylyl Cyclases

  James B. Ames;Alexander M. Dizhoor;Mitsuhiko Ikura;Krzysztof Palczewski

  204
  Citations

• The membrane guanylyl cyclase, retinal guanylyl cyclase-1, is activated through its intracellular domain.

  Richard P. Laura;Alexander M. Dizhoor;James B. Hurley

  201
  Citations

• Cloning, expression, and crystallization of recoverin, a calcium sensor in vision.

  Sanghamitra Ray;Sergey Zozulya;Gregory A. Niemi;Kevin M. Flaherty

  173
  Citations

• Ca2+ and Mg2+ Binding Properties of GCAP-1 EVIDENCE THAT Mg2+-BOUND FORM IS THE PHYSIOLOGICAL ACTIVATOR OF PHOTORECEPTOR GUANYLYL CYCLASE

  Igor V. Peshenko;Alexander M. Dizhoor

  157
  Citations

• Calcium Binding, but Not a Calcium-Myristoyl Switch, Controls the Ability of Guanylyl Cyclase-activating Protein GCAP-2 to Regulate Photoreceptor Guanylyl Cyclase

  Elena V. Olshevskaya;Robert E. Hughes;James B. Hurley;Alexander M. Dizhoor

  145
  Citations

• The Y99C mutation in guanylyl cyclase-activating protein 1 increases intracellular Ca2+ and causes photoreceptor degeneration in transgenic mice.

  Elena V. Olshevskaya;Peter D. Calvert;Michael L. Woodruff;Igor V. Peshenko

  143
  Citations

• Mg2+/Ca2+ cation binding cycle of guanylyl cyclase activating proteins (GCAPs): role in regulation of photoreceptor guanylyl cyclase.

  Alexander M. Dizhoor;Elena V. Olshevskaya;Igor V. Peshenko

  143
  Citations

• Inactivation of EF-hands Makes GCAP-2 (p24) a Constitutive Activator of Photoreceptor Guanylyl Cyclase by Preventing a Ca2+-induced “Activator-to-Inhibitor” Transition

  Alexander M. Dizhoor;James B. Hurley

  140
  Citations

• Determining consequences of retinal membrane guanylyl cyclase (RetGC1) deficiency in human Leber congenital amaurosis en route to therapy: residual cone-photoreceptor vision correlates with biochemical properties of the mutants

  Samuel G. Jacobson;Artur V. Cideciyan;Igor V. Peshenko;Alexander Sumaroka

  139
  Citations

• Recoverin's role: conclusion withdrawn

  James B. Hurley;Alexander M. Dizhoor;Sanghanitra Ray;Lubert Stryer

  133
  Citations