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Biology and Biochemistry

D-Index
59
Citations
10770
World Ranking
12711
National Ranking
5419

Research.com Recognitions

  • 2013 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1997 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

Gordon L. Fain is affiliated with the University of California, Los Angeles in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology as well as Neuroscience, with a specialized focus on Molecular Biology and Cellular and Molecular Neuroscience. Additional subfields include Endocrine and Autonomic Systems, Cognitive Neuroscience, and Cell Biology.

The main topics in Gordon L. Fain's work encompass:

  • Retinal Development and Disorders
  • Photoreceptor and optogenetics research
  • Circadian rhythm and melatonin
  • Receptor Mechanisms and Signaling
  • Neuroscience and Neuropharmacology Research
  • Neuroscience and Neural Engineering
  • Neurobiology and Insect Physiology Research

Several recent papers authored or coauthored by Fain illustrate the scope of their research, including:

  • "Elevated energy requirement of cone photoreceptors," 2020, published in Proceedings of the National Academy of Sciences
  • "Rod Photoreceptors Avoid Saturation in Bright Light by the Movement of the G Protein Transducin," 2021, Journal of Neuroscience
  • "Membrane conductances of mouse cone photoreceptors," 2020, The Journal of General Physiology
  • "Cones and cone pathways remain functional in advanced retinal degeneration," 2023, Current Biology
  • "Light responses of mammalian cones," 2021, Pflügers Archiv - European Journal of Physiology

Frequent collaborators in their work include:

  • Alapakkam P. Sampath
  • Rikard Frederiksen
  • Ala Morshedian
  • Norianne T. Ingram
  • Erika M. Ellis

Gordon L. Fain has published extensively in venues such as Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, Current Biology, bioRxiv (Cold Spring Harbor Laboratory), The Journal of Physiology, and the Proceedings of the National Academy of Sciences. These publications highlight ongoing contributions to areas ranging from molecular neuroscience to vision science.

Recognition for their scientific contributions includes being named a Fellow of the American Association for the Advancement of Science (AAAS) in 2013 and a Fellow of the John Simon Guggenheim Memorial Foundation in 1997.

Best Publications

  • Adaptation in Vertebrate Photoreceptors

    Gordon L. Fain;Hugh R. Matthews;M. Carter Cornwall;Yiannis Koutalos

  • Photoreceptor light adaptation is mediated by cytoplasmic calcium concentration.

    H. R. Matthews;R. L. W. Murphy;G. L. Fain;T. D. Lamb

  • ATP Consumption by Mammalian Rod Photoreceptors in Darkness and in Light

    Haruhisa Okawa;Alapakkam P. Sampath;Simon B. Laughlin;Gordon L. Fain

  • Phototransduction and the evolution of photoreceptors.

    Gordon L. Fain;Roger Hardie;Simon B. Laughlin

  • Sensitivity of toad rods: Dependence on wave‐length and background illumination.

    G L Fain

  • Bleached pigment activates transduction in isolated rods of the salamander retina.

    M C Cornwall;G L Fain

  • Measurement of cytoplasmic calcium concentration in the rods of wild-type and transducin knock-out mice

    Michael L. Woodruff;A. P. Sampath;Hugh R. Matthews;N. V. Krasnoperova

  • Spontaneous activity of opsin apoprotein is a cause of Leber congenital amaurosis.

    Michael L Woodruff;Zhongyan Wang;Hae Yun Chung;T Michael Redmond

  • Photoreceptor degeneration in vitamin A deprivation and retinitis pigmentosa: the equivalent light hypothesis.

    Gordon L. Fain;John E. Lisman

  • Membrane conductances of photoreceptors.

    G.L. Fain;G.L. Fain;J.E. Lisman;J.E. Lisman

  • Cytoplasmic calcium as the messenger for light adaptation in salamander rods

    G L Fain;T D Lamb;H R Matthews;R L Murphy

  • Contribution of a caesium-sensitive conductance increase to the rod photoresponse

    G. L. Fain;F. N. Quandt;B. L. Bastian;H. M. Gerschenfeld

  • Intracellular recordings from single rods and cones in the mudpuppy retina.

    Gordon L. Fain;John E. Dowling

  • AIPL1, the protein that is defective in Leber congenital amaurosis, is essential for the biosynthesis of retinal rod cGMP phosphodiesterase

    Xiaoqing Liu;Oleg V. Bulgakov;Xiao Hong Wen;Michael L. Woodruff

  • D-aspartate potentiates the effects of L-glutamate on horizontal cells in goldfish retina

    Andrew T. Ishida;Gordon L. Fain

  • Calcium and the mechanism of light adaptation in vertebrate photoreceptors.

    Gordon L. Fain;Hugh R. Matthews

  • Light adaptation in cone photoreceptors of the salamander: a role for cytoplasmic calcium.

    H. R. Matthews;G. L. Fain;R. L. W. Murphy;T. D. Lamb

  • Receptor Coupling in the Toad Retina

    Gordon L. Fain;Geoffrey H. Gold;John E. Dowling

  • The Y99C mutation in guanylyl cyclase-activating protein 1 increases intracellular Ca2+ and causes photoreceptor degeneration in transgenic mice.

    Elena V. Olshevskaya;Peter D. Calvert;Michael L. Woodruff;Igor V. Peshenko

  • Why photoreceptors die (and why they don't).

    Gordon L. Fain

Frequent Co-Authors

Alexander M. Dizhoor
Alexander M. Dizhoor Salus University
Debora B. Farber
Debora B. Farber University of California, Los Angeles
Paul A. Sieving
Paul A. Sieving University of California, Davis
John E. Lisman
John E. Lisman Brandeis University
Gabriel H. Travis
Gabriel H. Travis University of California, Los Angeles
John E. Dowling
John E. Dowling Harvard University
Tiansen Li
Tiansen Li National Institutes of Health
George Sachs
George Sachs University of California, Los Angeles
Rosalie K. Crouch
Rosalie K. Crouch Medical University of South Carolina
Stephen P. Goff
Stephen P. Goff Columbia University Medical Center

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