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Biology and Biochemistry

D-Index
55
Citations
10863
World Ranking
15053
National Ranking
6301

Overview

Debora B. Farber is a researcher affiliated with the University of California, Los Angeles in the United States, focusing on fields related to Biochemistry, Genetics, and Molecular Biology. Their work predominantly lies within the subfields of Molecular Biology, Cell Biology, and Developmental Neuroscience.

Their research explores several topics, including:

  • Retinal Development and Disorders
  • CRISPR and Genetic Engineering
  • RNA regulation and disease
  • Melanin and skin pigmentation
  • Neurogenesis and neuroplasticity mechanisms

Recent publications by Farber contribute to the understanding of genetic and cellular mechanisms in ocular and neurodevelopmental contexts. Notable papers include:

  • "CRISPR-AsCas12a Efficiently Corrects a GPR143 Intronic Mutation in Induced Pluripotent Stem Cells from an Ocular Albinism Patient" (2022, The CRISPR Journal)
  • "Decreased CREB phosphorylation impairs embryonic retinal neurogenesis in the Oa1-/- mouse model of Ocular albinism" (2024, bioRxiv, Cold Spring Harbor Laboratory)

Farber often collaborates with several researchers, including:

  • Simona Torriano
  • Edouard Baulier
  • Alejandro Garcia Diaz
  • Barbara Corneo
  • Sonia Guha

Their work has been published primarily in The CRISPR Journal and bioRxiv, indicating engagement with both peer-reviewed and preprint platforms within the field of genetic engineering and molecular biology.

Best Publications

  • Retinal degeneration in the rd mouse is caused by a defect in the β subunit of rod cGMP-phosphodiesterase

    Cathy Bowes;Tiansen Li;Michael Danciger;Michael Danciger;Leslie C. Baxter

  • Transfer of microRNAs by embryonic stem cell microvesicles.

    Alex Yuan;Erica L. Farber;Ana Lia Rapoport;Desiree Tejada

  • Estrogen receptor in the human eye: influence of gender and age on gene expression.

    Sandra B. Ogueta;Steven D. Schwartz;Clyde K. Yamashita;Debora B. Farber

  • Rod-cone dysplasia in Irish setters: a defect in cyclic GMP metabolism in visual cells

    G Aquirre;D Farber;R Lolley;RT Fletcher

  • A deletion in a photoreceptor-specific nuclear receptor mRNA causes retinal degeneration in the rd7 mouse

    Novrouz B. Akhmedov;Natik I. Piriev;Bo Chang;Ana Lia Rapoport

  • Retinal Degeneration in Mice Lacking the γ Subunit of the Rod cGMP Phosphodiesterase

    Stephen H. Tsang;Peter Gouras;Clyde K. Yamashita;Hild Kjeldbye

  • The rd mouse story: Seventy years of research on an animal model of inherited retinal degeneration

    Debora B. Farber;John G. Flannery;Cathy Bowes-Rickman

  • Degenerative changes in a retina affected with autosomal dominant retinitis pigmentosa.

    J G Flannery;D B Farber;A C Bird;D Bok

  • The β subunit of cyclic GMP phosphodiesterase mRNA is deficient in canine rod-cone dysplasia 1

    Debora B. Farber;Janet Seager Danciger;Gustavo Aguirre

  • A QTL on distal Chromosome 3 that influences the severity of light-induced damage to mouse photoreceptors

    Michael Danciger;Michael T. Matthes;Douglas Yasamura;Novrouz B. Akhmedov

  • Mutations in the PDE6B gene in autosomal recessive retinitis pigmentosa

    Michael Danciger;John Blaney;Y.Q. Gao;D.Y. Zhao

  • Progressive photoreceptor degeneration, outer segment dysplasia, and rhodopsin mislocalization in mice with targeted disruption of the retinitis pigmentosa-1 (Rp1) gene.

    Jiangang Gao;Kyeongmi Cheon;Steven Nusinowitz;Qin Liu

  • Retinoschisin, the X-linked retinoschisis protein, is a secreted photoreceptor protein, and is expressed and released by Weri-Rb1 cells.

    Celene Grayson;Silvia N.M. Reid;Juliet A. Ellis;Adam Rutherford

  • Identification and subcellular localization of the RP1 protein in human and mouse photoreceptors.

    Qin Liu;Jie Zhou;Stephen P. Daiger;Debora B. Farber

  • Encapsidated adenovirus mini-chromosome-mediated delivery of genes to the retina: application to the rescue of photoreceptor degeneration

    Rajendra Kumar-Singh;Debora B. Farber;Debora B. Farber

  • From mice to men: the cyclic GMP phosphodiesterase gene in vision and disease. The Proctor Lecture.

    D B Farber

  • Isolation and characterization of a novel oligodendrocyte-specific protein

    J. M. Bronstein;P. Popper;P. E. Micevych;D. B. Farber

  • Retinoschisin, a Photoreceptor-Secreted Protein, and Its Interaction with Bipolar and Müller Cells

    Silvia N. M. Reid;Clyde Yamashita;Debora B. Farber

  • A Nonsense Mutation in a Novel Gene Is Associated With Retinitis Pigmentosa in a Family Linked to the RP1 Locus

    Xavier Guillonneau;Natik I. Piriev;Michael Danciger;Michael Danciger;Christine A. Kozak

  • Retinoschisin, the X-linked Retinoschisis protein, is a secreted photoreceptor protein.

    D Trump;C Grayson;Snm Reid;J Sowden

Frequent Co-Authors

Christine A. Kozak
Christine A. Kozak National Institutes of Health
Claude G. Wasterlain
Claude G. Wasterlain University of California, Los Angeles
Samuel G. Jacobson
Samuel G. Jacobson University of Pennsylvania
John R. Heckenlively
John R. Heckenlively University of Michigan–Ann Arbor
Gustavo D. Aguirre
Gustavo D. Aguirre University of Pennsylvania
Gordon L. Fain
Gordon L. Fain University of California, Los Angeles
Stephen P. Goff
Stephen P. Goff Columbia University Medical Center
John G. Flannery
John G. Flannery University of California, Berkeley
David S. Williams
David S. Williams University of California, Los Angeles
Gerald J. Chader
Gerald J. Chader University of Southern California

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