Cell biology, Arp2/3 complex, Actin remodeling, MDia1 and Cytoskeleton are his primary areas of study. His work on Actin is typically connected to Membrane transport as part of general Cell biology study, connecting several disciplines of science. His Arp2/3 complex research includes themes of Golgi apparatus and Membrane tubulation.
The various areas that Matthew D. Welch examines in his Actin remodeling study include Paracytophagy and Profilin. His MDia1 study incorporates themes from Actin-binding protein, Actin-Related Protein 3, Actin-Related Protein 2-3 Complex, Lamellipodium and Actin nucleation. Matthew D. Welch has included themes like N-Formylmethionine leucyl-phenylalanine and Chemotaxis in his Actin-binding protein study.
His scientific interests lie mostly in Cell biology, Arp2/3 complex, Actin, Cytoskeleton and Actin remodeling. Matthew D. Welch interconnects Actin-binding protein, Profilin, Actin cytoskeleton, Actin-Related Protein 2-3 Complex and Actin nucleation in the investigation of issues within Cell biology. His work deals with themes such as MDia1, Paracytophagy, Actin remodeling of neurons and Microfilament, which intersect with Arp2/3 complex.
His MDia1 research is multidisciplinary, incorporating perspectives in Formins and Lamellipodium. His work carried out in the field of Actin brings together such families of science as Cytoplasm, Intracellular parasite, Listeria monocytogenes, Microtubule and Motility. His Cytoskeleton research incorporates elements of Pseudopodia and Effector.
His primary scientific interests are in Cell biology, Rickettsia, Innate immune system, Microbiology and Bacteria. When carried out as part of a general Cell biology research project, his work on Actin and Motility is frequently linked to work in Competition and Palmitoylation, therefore connecting diverse disciplines of study. The study incorporates disciplines such as Actin cytoskeleton and Transduction in addition to Actin.
His Rickettsia study integrates concerns from other disciplines, such as Host cell cytosol, Intracellular parasite and Virulence. His Innate immune system study combines topics in areas such as Listeria monocytogenes and Intracellular. The Microbiology study combines topics in areas such as Interferon and Spotted fever.
Matthew D. Welch mostly deals with Cell biology, Rickettsia, Innate immune system, Motility and Virulence. He works in the field of Cell biology, namely Actin. His Actin research incorporates themes from Cell, Nuclear localization sequence, Actin cytoskeleton and Late protein.
His Innate immune system research is multidisciplinary, relying on both Listeria monocytogenes, Secretion and Intracellular. His study in Motility is interdisciplinary in nature, drawing from both Arp2/3 complex, Cytoplasm, Nuclear pore and Viral protein. Matthew D. Welch has researched Virulence in several fields, including Ubiquitin and Immune system, Intracellular parasite.
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The ARP2/3 complex: an actin nucleator comes of age
Erin D. Goley;Matthew D. Welch.
Nature Reviews Molecular Cell Biology (2006)
A nucleator arms race: cellular control of actin assembly
Kenneth G. Campellone;Matthew D. Welch.
Nature Reviews Molecular Cell Biology (2010)
Actin polymerization is induced by Arp2/3 protein complex at the surface of Listeria monocytogenes.
Matthew D. Welch;Akihiro Iwamatsu;Timothy J. Mitchison.
Cellular control of actin nucleation
Matthew D. Welch;R. Dyche Mullins.
Annual Review of Cell and Developmental Biology (2002)
Interaction of human Arp2/3 complex and the Listeria monocytogenes ActA protein in actin filament nucleation.
Matthew D. Welch;Jody Rosenblatt;Justin Skoble;Daniel A. Portnoy.
The Human Arp2/3 Complex Is Composed of Evolutionarily Conserved Subunits and Is Localized to Cellular Regions of Dynamic Actin Filament Assembly
Matthew D. Welch;Angela H. DePace;Suzie Verma;Akihiro Iwamatsu.
Journal of Cell Biology (1997)
Actin-based motility of intracellular pathogens.
Edith Gouin;Matthew D Welch;Pascale Cossart.
Current Opinion in Microbiology (2005)
The Wiskott–Aldrich syndrome protein directs actin-based motility by stimulating actin nucleation with the Arp2/3 complex
Defne Yarar;Wayne To;Arie Abo;Matthew D. Welch.
Current Biology (1999)
Mycobacterium marinum Escapes from Phagosomes and Is Propelled by Actin-based Motility
Luisa M Stamm;J Hiroshi Morisaki;Lian-Yong Gao;Robert L. Jeng.
Journal of Experimental Medicine (2003)
Spatial control of actin polymerization during neutrophil chemotaxis.
Orion D. Weiner;Guy Servant;Matthew D. Welch;Matthew D. Welch;Timothy J. Mitchison;Timothy J. Mitchison.
Nature Cell Biology (1999)
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