World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
14736
World Ranking
16479
National Ranking
6822

Overview

Matthew D. Welch is affiliated with the University of California, Berkeley in the United States. Their research contributions span across multiple fields, primarily focusing on biochemistry, genetics, and molecular biology, as well as medicine. The scientist's work also deeply engages with subfields such as molecular biology, parasitology, epidemiology, public health, environmental and occupational health, and infectious diseases.

The research topics covered in their publications show a strong emphasis on infectious diseases and cellular interactions. Principal themes include:

  • Vector-borne infectious diseases
  • Bacterial biofilms and quorum sensing
  • Mosquito-borne diseases and control
  • Insect symbiosis and bacterial influences
  • Cellular mechanics and interactions
  • Viral infections and vectors
  • Vibrio bacteria research studies

Among the recent papers are the following works:

  • "Inflammasome-mediated antagonism of type I interferon enhances Rickettsia pathogenesis" (2020), published in Nature Microbiology
  • "Lysine methylation shields an intracellular pathogen from ubiquitylation and autophagy" (2021), published in Science Advances
  • "Mechanical competition triggered by innate immune signaling drives the collective extrusion of bacterially infected epithelial cells" (2021), published in Developmental Cell
  • "A patatin-like phospholipase mediates Rickettsia parkeri escape from host membranes" (2022), published in Nature Communications
  • "Interferon receptor-deficient mice are susceptible to eschar-associated rickettsiosis" (2021), published in eLife

The scientist frequently publishes in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Biology of the Cell
  • Nature Communications
  • eLife
  • Biophysical Journal

Collaborative research is an integral part of the scientist's output, with frequent co-authors including Patrik Engström, Thomas Burke, Cuong J. Tran, Ingeborg M. Langohr, and E Bastounis.

Best Publications

  • The ARP2/3 complex: an actin nucleator comes of age

    Erin D. Goley;Matthew D. Welch

  • A nucleator arms race: cellular control of actin assembly

    Kenneth G. Campellone;Matthew D. Welch

  • Actin polymerization is induced by Arp2/3 protein complex at the surface of Listeria monocytogenes.

    Matthew D. Welch;Akihiro Iwamatsu;Timothy J. Mitchison

  • Cellular control of actin nucleation

    Matthew D. Welch;R. Dyche Mullins

  • Interaction of human Arp2/3 complex and the Listeria monocytogenes ActA protein in actin filament nucleation.

    Matthew D. Welch;Jody Rosenblatt;Justin Skoble;Daniel A. Portnoy

  • The Human Arp2/3 Complex Is Composed of Evolutionarily Conserved Subunits and Is Localized to Cellular Regions of Dynamic Actin Filament Assembly

    Matthew D. Welch;Angela H. DePace;Suzie Verma;Akihiro Iwamatsu

  • Actin-based motility of intracellular pathogens.

    Edith Gouin;Matthew D Welch;Pascale Cossart

  • The Wiskott–Aldrich syndrome protein directs actin-based motility by stimulating actin nucleation with the Arp2/3 complex

    Defne Yarar;Wayne To;Arie Abo;Matthew D. Welch

  • Mycobacterium marinum Escapes from Phagosomes and Is Propelled by Actin-based Motility

    Luisa M Stamm;J Hiroshi Morisaki;Lian-Yong Gao;Robert L. Jeng

  • Spatial control of actin polymerization during neutrophil chemotaxis.

    Orion D. Weiner;Guy Servant;Matthew D. Welch;Matthew D. Welch;Timothy J. Mitchison;Timothy J. Mitchison

  • Formation of filopodia-like bundles in vitro from a dendritic network.

    Danijela Vignjevic;Defne Yarar;Matthew D. Welch;John Peloquin

  • WHAMM Is an Arp2/3 Complex Activator That Binds Microtubules and Functions in ER to Golgi Transport

    Kenneth Geno Campellone;Neil J. Webb;Elizabeth A. Znameroski;Matthew D. Welch

  • ACTIN DYNAMICS IN VIVO

    Matthew D Welch;Aneil Mallavarapu;Jody Rosenblatt;Timothy J Mitchison

  • Actin-based motility drives baculovirus transit to the nucleus and cell surface

    Taro Ohkawa;Loy E. Volkman;Matthew D. Welch

  • Arp2/3-mediated actin-based motility: a tail of pathogen abuse.

    Matthew D. Welch;Michael Way

  • New mechanisms and functions of actin nucleation

    Elif Nur Firat-Karalar;Matthew D Welch

  • Three regions within ActA promote Arp2/3 complex-mediated actin nucleation and Listeria monocytogenes motility.

    Justin Skoble;Daniel A. Portnoy;Matthew D. Welch

  • Pathogens and polymers: microbe-host interactions illuminate the cytoskeleton.

    Cat M. Haglund;Matthew D. Welch

  • WASH and the Arp2/3 complex regulate endosome shape and trafficking.

    Steve N. Duleh;Matthew D. Welch

  • Identification of a bacterial factor required for actin-based motility of Burkholderia pseudomallei.

    Mark P. Stevens;Joanne M. Stevens;Robert L. Jeng;Lowrie A. Taylor

Frequent Co-Authors

Timothy J. Mitchison
Timothy J. Mitchison Harvard University
Julie A. Theriot
Julie A. Theriot University of Washington
David G. Drubin
David G. Drubin University of California, Berkeley
Loy E. Volkman
Loy E. Volkman University of California, Berkeley
Daniel A. Portnoy
Daniel A. Portnoy University of California, Berkeley
Hong-Wei Wang
Hong-Wei Wang Tsinghua University
Tatyana Svitkina
Tatyana Svitkina University of Pennsylvania
Russell E. Vance
Russell E. Vance University of California, Berkeley
Daniel K. Nomura
Daniel K. Nomura University of California, Berkeley
John M. Leong
John M. Leong Tufts University

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