John M. Leong spends much of his time researching Borrelia burgdorferi, Microbiology, Actin, Cell biology and Bacterial outer membrane. His Borrelia burgdorferi study combines topics in areas such as Binding protein, Integrin and Recombinant DNA. John M. Leong works mostly in the field of Microbiology, limiting it down to topics relating to Fibronectin and, in certain cases, Cell adhesion molecule, as a part of the same area of interest.
He combines subjects such as Plasma protein binding, Signal transducing adaptor protein, Cytoskeleton, Protein structure and Effector with his study of Actin. In Signal transducing adaptor protein, John M. Leong works on issues like Intimin, which are connected to Enteropathogenic Escherichia coli. The various areas that John M. Leong examines in his Bacterial outer membrane study include Peptide sequence, Signal transduction and Siderophore.
Microbiology, Cell biology, Borrelia burgdorferi, Immunology and Effector are his primary areas of study. His Microbiology research includes elements of Bacterial adhesin, Escherichia coli, Virology and Intimin. His work deals with themes such as Biochemistry and Actin cytoskeleton, Cytoskeleton, which intersect with Cell biology.
His research investigates the connection between Borrelia burgdorferi and topics such as Lyme disease that intersect with issues in LYME. In his research on the topic of Immunology, Lung, Inflammation, Neutrophil elastase and Adenosine is strongly related with Streptococcus pneumoniae. His Effector research focuses on subjects like Secretion, which are linked to Host cell plasma membrane.
John M. Leong mainly focuses on Microbiology, Streptococcus pneumoniae, Pathogen, Immunology and Inflammation. His biological study spans a wide range of topics, including Borrelia burgdorferi, Lyme disease, Receptor, Innate immune system and Shiga toxin. His research in Borrelia burgdorferi intersects with topics in Bacterial adhesin, Tissue tropism and Cell biology.
He has researched Streptococcus pneumoniae in several fields, including Neutrophil elastase, Ex vivo, Proinflammatory cytokine and Lung. The study incorporates disciplines such as Secretion and Pneumonia in addition to Immunology. The concepts of his Inflammation study are interwoven with issues in Molecular biology and Pneumolysin.
John M. Leong focuses on Microbiology, Streptococcus pneumoniae, Inflammation, Immunology and Lung. His Microbiology study focuses on Pathogen in particular. His Pathogen research incorporates themes from Borrelia burgdorferi, Lyme disease, Innate immune system, Lytic cycle and Shiga toxin.
His studies deal with areas such as Factor H, Virology, Evasion, Antimicrobial peptides and Virulence as well as Borrelia burgdorferi. His Inflammation research incorporates elements of Systemic disease, Pneumococcal infections and Pneumonia. His Pneumococcal pneumonia study integrates concerns from other disciplines, such as Extracellular, Receptor and Adenosine.
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Experimental Observation of a Heavy Particle $J$
J. J. Aubert;U. Becker;P. J. Biggs;J. Burger.
Physical Review Letters (1974)
Multiple β1 chain integrins are receptors for invasin, a protein that promotes bacterial penetration into mammalian cells
Ralph R. Isberg;John M. Leong.
TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by gram-negative bacteria.
Vijay A.K. Rathinam;Sivapriya Kailasan Vanaja;Sivapriya Kailasan Vanaja;Lisa Waggoner;Anna Sokolovska.
B1b Lymphocytes Confer T Cell-Independent Long-Lasting Immunity
Kishore R. Alugupalli;John M. Leong;Robert T. Woodland;Masamichi Muramatsu.
EspFU Is a Translocated EHEC Effector that Interacts with Tir and N-WASP and Promotes Nck-Independent Actin Assembly
Kenneth Geno Campellone;Douglas Robbins;John M. Leong.
Developmental Cell (2004)
Association of treatment-resistant chronic Lyme arthritis with HLA-DR4 and antibody reactivity to OspA and OspB of Borrelia burgdorferi.
R A Kalish;J M Leong;A C Steere.
Infection and Immunity (1993)
Identification of the integrin binding domain of the Yersinia pseudotuberculosis invasin protein.
J M Leong;R S Fournier;R R Isberg.
The EMBO Journal (1990)
Integrin alpha IIb beta 3 mediates binding of the Lyme disease agent Borrelia burgdorferi to human platelets
Jenifer Coburn;John M. Leong;John K. Erban.
Proceedings of the National Academy of Sciences of the United States of America (1993)
A tyrosine-phosphorylated 12-amino-acid sequence of enteropathogenic Escherichia coli Tir binds the host adaptor protein Nck and is required for Nck localization to actin pedestals.
Kenneth Geno Campellone;Andrew Giese;Donald J. Tipper;John M. Leong.
Molecular Microbiology (2002)
Hierarchical regulation of WASP/WAVE proteins.
Shae B. Padrick;Hui Chun Cheng;Ayman M. Ismail;Sanjay C. Panchal.
Molecular Cell (2008)
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