What is he best known for?
The fields of study he is best known for:
John M. Leong spends much of his time researching Borrelia burgdorferi, Microbiology, Actin, Cell biology and Bacterial outer membrane.
His Borrelia burgdorferi study combines topics in areas such as Binding protein, Integrin and Recombinant DNA.
John M. Leong works mostly in the field of Microbiology, limiting it down to topics relating to Fibronectin and, in certain cases, Cell adhesion molecule, as a part of the same area of interest.
He combines subjects such as Plasma protein binding, Signal transducing adaptor protein, Cytoskeleton, Protein structure and Effector with his study of Actin.
In Signal transducing adaptor protein, John M. Leong works on issues like Intimin, which are connected to Enteropathogenic Escherichia coli.
The various areas that John M. Leong examines in his Bacterial outer membrane study include Peptide sequence, Signal transduction and Siderophore.
His most cited work include:
- Experimental Observation of a Heavy Particle $J$ (890 citations)
- Multiple β1 chain integrins are receptors for invasin, a protein that promotes bacterial penetration into mammalian cells (692 citations)
- TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by gram-negative bacteria. (489 citations)
What are the main themes of his work throughout his whole career to date?
Microbiology, Cell biology, Borrelia burgdorferi, Immunology and Effector are his primary areas of study.
His Microbiology research includes elements of Bacterial adhesin, Escherichia coli, Virology and Intimin.
His work deals with themes such as Biochemistry and Actin cytoskeleton, Cytoskeleton, which intersect with Cell biology.
His research investigates the connection between Borrelia burgdorferi and topics such as Lyme disease that intersect with issues in LYME.
In his research on the topic of Immunology, Lung, Inflammation, Neutrophil elastase and Adenosine is strongly related with Streptococcus pneumoniae.
His Effector research focuses on subjects like Secretion, which are linked to Host cell plasma membrane.
He most often published in these fields:
- Microbiology (50.54%)
- Cell biology (20.65%)
- Borrelia burgdorferi (20.65%)
What were the highlights of his more recent work (between 2016-2021)?
- Microbiology (50.54%)
- Streptococcus pneumoniae (10.33%)
- Pathogen (11.41%)
In recent papers he was focusing on the following fields of study:
John M. Leong mainly focuses on Microbiology, Streptococcus pneumoniae, Pathogen, Immunology and Inflammation.
His biological study spans a wide range of topics, including Borrelia burgdorferi, Lyme disease, Receptor, Innate immune system and Shiga toxin.
His research in Borrelia burgdorferi intersects with topics in Bacterial adhesin, Tissue tropism and Cell biology.
He has researched Streptococcus pneumoniae in several fields, including Neutrophil elastase, Ex vivo, Proinflammatory cytokine and Lung.
The study incorporates disciplines such as Secretion and Pneumonia in addition to Immunology.
The concepts of his Inflammation study are interwoven with issues in Molecular biology and Pneumolysin.
Between 2016 and 2021, his most popular works were:
- Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival (37 citations)
- The Alpha-Tocopherol Form of Vitamin E Boosts Elastase Activity of Human PMNs and Their Ability to Kill Streptococcus pneumoniae. (33 citations)
- Prophage induction, but not production of phage particles, is required for lethal disease in a microbiome-replete murine model of enterohemorrhagic E. coli infection. (20 citations)
In his most recent research, the most cited papers focused on:
John M. Leong focuses on Microbiology, Streptococcus pneumoniae, Inflammation, Immunology and Lung.
His Microbiology study focuses on Pathogen in particular.
His Pathogen research incorporates themes from Borrelia burgdorferi, Lyme disease, Innate immune system, Lytic cycle and Shiga toxin.
His studies deal with areas such as Factor H, Virology, Evasion, Antimicrobial peptides and Virulence as well as Borrelia burgdorferi.
His Inflammation research incorporates elements of Systemic disease, Pneumococcal infections and Pneumonia.
His Pneumococcal pneumonia study integrates concerns from other disciplines, such as Extracellular, Receptor and Adenosine.
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