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Brigitte T. Huber

Brigitte T. Huber

D-Index & Metrics

Immunology

D-Index
49
Citations
8213
World Ranking
4355
National Ranking
1979

Overview

Brigitte T. Huber is affiliated with Tufts University in the United States. Their research primarily centers on immunology and microbiology, with additional focus in medicine. The scientist's subfields of study include immunology as well as radiology, nuclear medicine, and imaging.

Their contributions to academic literature include exploration of key topics such as:

  • Monoclonal and Polyclonal Antibodies Research
  • Immunotherapy and Immune Responses
  • Galectins and Cancer Biology

Huber's recent publication record includes work published in "The Journal of Immunology." This includes the 2024 paper titled Complement receptor 2 as a novel therapeutic target to suppress germinal center-derived autoantibody production in a SLE mouse model. The research is associated with Ajitanuj Rattan as an author.

Frequent collaborators in their research efforts include:

  • Ajitanuj Rattan
  • Danni Zhu
  • V. Michael Holers
  • Michael C. Carroll

Their scholarly output reflects engagement with both fundamental and applied aspects of immunological science, integrating molecular targets and mechanisms relevant to disease models such as systemic lupus erythematosus (SLE).

Best Publications

  • Identification of LFA-1 as a Candidate Autoantigen in Treatment-Resistant Lyme Arthritis

    Dawn M. Gross;Thomas Forsthuber;Magdalena Tary-Lehmann;Carey Etling

  • Linkage of Mls genes to endogenous mammary tumour viruses of inbred mice.

    Wayne N. Frankel;Christine Rudy;John M. Coffin;Brigitte T. Huber

  • Epstein-Barr Virus Transactivates the Human Endogenous Retrovirus HERV-K18 that Encodes a Superantigen

    Natalie Sutkowski;Bernard Conrad;David A Thorley-Lawson;Brigitte T Huber

  • Cholera Toxin Discriminates Between T Helper 1 and 2 Cells in T Cell Receptor-Mediated Activation: Role of cAMP in T Cell Proliferation

    Eduardo Muñoz;Ana M. Zubiaga;Martha Merrow;Nicholas P. Sauter

  • Cell-mediated immunity: delayed-type hypersensitivity and cytotoxic responses are mediated by different T-cell subclasses.

    B Huber;O Devinsky;R K Gershon;H Cantor

  • Inhibition of dipeptidyl aminopeptidase IV (DP-IV) by Xaa-boroPro dipeptides and use of these inhibitors to examine the role of DP-IV in T-cell function.

    G R Flentke;E Munoz;B T Huber;A G Plaut

  • Identification of a B-cell surface structure involved in antigen-dependent triggering: absence of this structure on B cells from CBA/N mutant mice.

    B Huber;R K Gershon;H Cantor

  • IL-4 and IL-2 selectively rescue Th cell subsets from glucocorticoid-induced apoptosis.

    A M Zubiaga;E Munoz;B T Huber

  • T Helper 1 Response Is Dominant and Localized to the Synovial Fluid in Patients with Lyme Arthritis

    Dawn M. Gross;Allen C. Steere;Brigitte T. Huber

  • Human immunodeficiency virus 1 Tat binds to dipeptidyl aminopeptidase IV (CD26): a possible mechanism for Tat's immunosuppressive activity.

    William G. Gutheil;Meena Subramanyam;George R. Flentke;David G. Sanford

  • Interferon-alpha-induced endogenous superantigen. a model linking environment and autoimmunity.

    Yves Stauffer;Samuel Marguerat;Françoise Meylan;Catherine Ucla

  • Contamination of human DNA samples with mouse DNA can lead to false detection of XMRV-like sequences.

    Brendan Oakes;Albert K Tai;Oya Cingöz;Madeleine H Henefield

  • An Epstein-Barr virus-associated superantigen.

    N Sutkowski;T Palkama;C Ciurli;R P Sekaly

  • Autoimmune Mechanisms in Antibiotic Treatment-Resistant Lyme Arthritis

    Allen C Steere;Dawn Gross;Abbie L Meyer;Brigitte T Huber

  • Mechanism of HIV-1 Tat induced inhibition of antigen-specific T cell responsiveness.

    M Subramanyam;W G Gutheil;W W Bachovchin;B T Huber

  • Direct enumeration of Borrelia-reactive CD4 T cells ex vivo by using MHC class II tetramers.

    Abbie L. Meyer;Christina Trollmo;Frances Crawford;Philippa Marrack

  • Vitamin E-Enhanced IL-2 Production in Old Mice: Naive But Not Memory T Cells Show Increased Cell Division Cycling and IL-2-Producing Capacity

    Oskar Adolfsson;Brigitte T. Huber;Simin Nikbin Meydani;Simin Nikbin Meydani

  • Independent differentiative pathways of ly1 and ly23 subclasses of t cells. Experimental production of mice deprived of selected t-cell subclasses.

    B Huber;H Cantor;F W Shen;E A Boyse

  • IL-1 activates two separate signal transduction pathways in T helper type II cells.

    E Muñoz;U Beutner;A Zubiaga;B T Huber

  • B cells are essential for murine mammary tumor virus transmission, but not for presentation of endogenous superantigens

    Ulrich Beutner;Eliyahu Kraus;Daisuke Kitamura;Klaus Rajewsky

  • Two monoclonal rat antibodies with specificity for the beta-chain variable region V beta 6 of the murine T-cell receptor.

    J Payne;B T Huber;N A Cannon;R Schneider

  • Molecular mimicry in Lyme arthritis demonstrated at the single cell level: LFA-1 alpha L is a partial agonist for outer surface protein A-reactive T cells.

    Christina Trollmo;Abbie L. Meyer;Allen C. Steere;David A. Hafler

  • Association of antibiotic treatment-resistant Lyme arthritis with T cell responses to dominant epitopes of outer surface protein A of Borrelia burgdorferi.

    Jie Chen;Jodie A. Field;Lisa Glickstein;Philip J. Molloy

  • Molecular Pathogenesis of Chronic Lymphocytic Leukemia

    Alexey V. Danilov;Olga V. Danilova;Andreas K. Klein;Brigitte T. Huber

Frequent Co-Authors

Eduardo Muñoz
Eduardo Muñoz University of Córdoba
Allen C. Steere
Allen C. Steere Harvard University
Richard K. Gershon
Richard K. Gershon Yale University
Simin Nikbin Meydani
Simin Nikbin Meydani Tufts University
Harvey Cantor
Harvey Cantor Harvard University
David A. Thorley-Lawson
David A. Thorley-Lawson Tufts University
William W. Bachovchin
William W. Bachovchin Tufts University
Baruj Benacerraf
Baruj Benacerraf Harvard University
David A. Hafler
David A. Hafler Yale University
John M. Coffin
John M. Coffin Tufts University

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