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Immunology

D-Index
56
Citations
18456
World Ranking
3670
National Ranking
87

Overview

Hans Acha-Orbea is affiliated with the University of Lausanne in Switzerland. Their research primarily spans the fields of Immunology and Microbiology, with additional contributions to Medicine. The scientist's work is notably concentrated in Immunology as a subfield, alongside Molecular Biology, Oncology, Rheumatology, and Radiology, Nuclear Medicine and Imaging.

The central themes in their research encompass Immunotherapy and Immune Responses, Immune Cell Function and Interaction, Immune Response and Inflammation, interferon and immune responses, Inflammasome and immune disorders, IgG4-Related and Inflammatory Diseases, as well as Monoclonal and Polyclonal Antibodies Research.

Frequent publication venues for Hans Acha-Orbea include the European Journal of Immunology and Frontiers in Immunology, each featuring multiple publications. Additional venues where their work has appeared include the International Journal of Molecular Sciences, The Journal of Immunology, and Arthritis Research & Therapy.

Among recent published papers are:

  • Novel Autoantibody Signatures in Sera of Patients with Pancreatic Cancer, Chronic Pancreatitis and Autoimmune Pancreatitis: A Protein Microarray Profiling Approach (2020), International Journal of Molecular Sciences
  • Zbtb10 transcription factor is crucial for murine cDC1 activation and cytokine secretion (2021), European Journal of Immunology
  • IL10- and IL35-Secreting MutuDC Lines Act in Cooperation to Inhibit Memory T Cell Activation Through LAG-3 Expression (2021), Frontiers in Immunology
  • SMRT and NCoR1 fine-tune inflammatory versus tolerogenic balance in dendritic cells by differentially regulating STAT3 signaling (2022), Frontiers in Immunology
  • NCoR1 fine-tunes type-I IFN response in cDC1 dendritic cells by directly regulating Myd88-IRF7 axis under TLR9 (2020), European Journal of Immunology

Hans Acha-Orbea has collaborated frequently with several co-authors, notably Kaushik Sen and Sunil K. Raghav, both with four joint publications, as well as Shuchi Smita, Viplov Kumar Biswas, and Abdul Ahad, who have three joint publications each.

Best Publications

  • BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth.

    Pascal Schneider;Fabienne Mackay;Véronique Steiner;Kay Hofmann

  • T-cell receptor V beta use predicts reactivity and tolerance to Mlsa-encoded antigens.

    H. Robson MacDonald;Reto Schneider;Rosemary K. Lees;Rawleigh C. Howe

  • Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention

    Hans Acha-Orbea;Dennis J. Mitchell;Luika Timmermann;David C. Wraith

  • Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells.

    Alexander Link;Tobias K Vogt;Stéphanie Favre;Mirjam R Britschgi

  • A molecular basis for MHC class II--associated autoimmunity

    J A Todd;H Acha-Orbea;J I Bell;N Chao

  • The first external domain of the nonobese diabetic mouse class II I-A beta chain is unique.

    Hans Acha-Orbea;Hugh O. McDevitt

  • Less mortality but more relapses in experimental allergic encephalomyelitis in CD8-/- mice.

    Dow-Rhoon Koh;Wai-Ping Fung-Leung;Alexandra Ho;Dawn Gray

  • Identification of proteoglycans as the APRIL-specific binding partners

    Karine Ingold;Adrian Zumsteg;Aubry Tardivel;Bertrand Huard

  • Leishmania RNA virus controls the severity of mucocutaneous leishmaniasis.

    Annette Ives;Catherine Ronet;Florence Prevel;Giulia Ruzzante

  • IL-4 Rapidly Produced by Vβ4 Vα8 CD4+ T Cells Instructs Th2 Development and Susceptibility to Leishmania major in BALB/c Mice

    Pascal Launois;Ivan Maillard;Sabine Pingel;Kristin G. Swihart

  • Prevention of diabetes in nonobese diabetic mice by tumor necrosis factor (TNF): similarities between TNF-alpha and interleukin 1.

    Chaim O. Jacob;Sadakazu Aiso;Sara A. Michie;Hugh O. Mcdevitt

  • Complement facilitates early prion pathogenesis.

    M A Klein;P S Kaeser;P Schwarz;H Weyd

  • TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablasts

    Claudia Bossen;Teresa G. Cachero;Aubry Tardivel;Karine Ingold

  • Clonal deletion of V beta 14-bearing T cells in mice transgenic for mammary tumour virus.

    Hans Acha-Orbea;Alexander N. Shakhov;Leo Scarpellino;Edith Kolb

  • Mini-review: Specificity and expression of CIITA, the master regulator of MHC class II genes

    Salomé LeibundGut-Landmann;Jean-Marc Waldburger;Michal Krawczyk;Luc A Otten

  • Cytotoxic T cells deficient in both functional fas ligand and perforin show residual cytolytic activity yet lose their capacity to induce lethal acute graft-versus-host disease

    Unknown

  • T Helper 1 (Th1) and Th2 Characteristics Start to Develop During T Cell Priming and Are Associated with an Immediate Ability to Induce Immunoglobulin Class Switching

    Kai-Michael Toellner;Sanjiv A. Luther;Daniel M.-Y. Sze;Richard K.-W. Choy

  • Effects of mycophenolic acid on human immunodeficiency virus infection in vitro and in vivo.

    Aude G. Chapuis;G. Paolo Rizzardi;Claudia D'Agostino;Antoine Attinger

  • T cell recognition as the target for immune intervention in autoimmune disease

    David C. Wraith;Hugh O. McDevitt;Lawrence Steinman;Hans Acha-Orbea

  • Ectopic Lymphoid-Organ Development Occurs through Interleukin 7-Mediated Enhanced Survival of Lymphoid-Tissue-Inducer Cells

    Dominik Meier;Caroline Bornmann;Stephane Chappaz;Sandrine Schmutz

  • CD4+CD3− Cells Induce Peyer's Patch Development: Role of α4β1 Integrin Activation by CXCR5

    D Finke;H Acha-Orbea;H Acha-Orbea;A Mattis;M Lipp

  • Superantigen-induced immune stimulation amplifies mouse mammary tumor virus infection and allows virus transmission

    Werner Held;Gary A. Waanders;Alexander N. Shakhov;Léonardo Scarpellino

Frequent Co-Authors

Walter Reith
Walter Reith University of Geneva
Sanjiv A. Luther
Sanjiv A. Luther University of Lausanne
Ivan Maillard
Ivan Maillard University of Pennsylvania
H. Robson MacDonald
H. Robson MacDonald University of Lausanne
Ken Shortman
Ken Shortman Walter and Eliza Hall Institute of Medical Research
Fabienne Tacchini-Cottier
Fabienne Tacchini-Cottier University of Lausanne
Salomé LeibundGut-Landmann
Salomé LeibundGut-Landmann University of Zurich
Pascal Schneider
Pascal Schneider University of Lausanne
Andreas Strasser
Andreas Strasser Walter and Eliza Hall Institute of Medical Research
Jacques A. Louis
Jacques A. Louis Institut Pasteur

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