Jacques A. Louis

Overview

Best Publications

• Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response.

  Frank Mattner;Jeanne Magram;Jessica Ferrante;Pascal Launois

  704
  Citations

• A limiting dilution assay for quantifying Leishmania major in tissues of infected mice

  Rg. Titus;Maurice Marchand;Thierry Boon;Ja. Louis

  645
  Citations

• Natural Killer Cells Activated by MHC Class ILow Targets Prime Dendritic Cells to Induce Protective CD8 T Cell Responses

  Ralph Mocikat;Heidi Braumüller;Heidi Braumüller;Alain Gumy;Oliver Egeter

  600
  Citations

• IL-4 Rapidly Produced by Vβ4 Vα8 CD4+ T Cells Instructs Th2 Development and Susceptibility to Leishmania major in BALB/c Mice

  Pascal Launois;Ivan Maillard;Sabine Pingel;Kristin G. Swihart

  455
  Citations

• IL-4 instructs TH1 responses and resistance to Leishmania major in susceptible BALB/c mice.

  Tilo Biedermann;Stephan Zimmermann;Stephan Zimmermann;Hayo Himmelrich;Alain Gumy

  404
  Citations

• An immunomodulatory function for neutrophils during the induction of a CD4+ Th2 response in BALB/c mice infected with Leishmania major.

  Fabienne Tacchini-Cottier;C. Zweifel;Y. Belkaid;C. Mukankundiye

  360
  Citations

• Mice from a genetically resistant background lacking the interferon gamma receptor are susceptible to infection with Leishmania major but mount a polarized T helper cell 1-type CD4+ T cell response

  K. Swihart;U. Fruth;N. Messmer;K. Hug

  344
  Citations

• L3T4+ T lymphocytes play a major role in the pathogenesis of murine cerebral malaria.

  G E Grau;P F Piguet;H D Engers;J A Louis

  328
  Citations

• Therapeutic effect of anti-L3T4 monoclonal antibody GK1.5 on cutaneous leishmaniasis in genetically-susceptible BALB/c mice.

  R G Titus;R Ceredig;J C Cerottini;J A Louis

  280
  Citations

• Mycobacterial heat-shock proteins as carrier molecules. II: The use of the 70-kDa mycobacterial heat-shock protein as carrier for conjugated vaccines can circumvent the need for adjuvants and Bacillus Calmette Guérin priming.

  Christy Barrios;Alexander R. Lussow;Jan Van Embden;Ruurd Van Der Zee

  255
  Citations

• Mycobacterial heat-shock proteins as carrier molecules.

  A R Lussow;C Barrios;J van Embden;R Van der Zee

  249
  Citations

• In susceptible mice, Leishmania major induce very rapid interleukin-4 production by CD4+ T cells which are NK1.1-.

  Launois P;Ohteki T;Swihart K;MacDonald Hr

  242
  Citations

• The IL-4 rapidly produced in BALB/c mice after infection with Leishmania major down-regulates IL-12 receptor beta 2-chain expression on CD4+ T cells resulting in a state of unresponsiveness to IL-12.

  Hayo Himmelrich;Carlos Parra-Lopez;Fabienne Tacchini-Cottier;Jacques A. Louis

  223
  Citations

• The early IL-4 response to Leishmania major and the resulting Th2 cell maturation steering progressive disease in BALB/c mice are subject to the control of regulatory CD4+CD25+ T cells.

  Abraham Aseffa;Alain Gumy;Pascal Launois;H. Robson MacDonald

  215
  Citations

• Regulatory B Cells Shape the Development of Th2 Immune Responses in BALB/c Mice Infected with Leishmania major Through IL-10 Production

  Catherine Ronet;Catherine Ronet;Yazmin Hauyon-La Torre;Yazmin Hauyon-La Torre;Mélanie Revaz-Breton;Mélanie Revaz-Breton;Béatris Mastelic;Béatris Mastelic

  203
  Citations

• In BALB/c Mice, IL-4 Production During the Initial Phase of Infection with Leishmania major Is Necessary and Sufficient to Instruct Th2 Cell Development Resulting in Progressive Disease

  Hayo Himmelrich;Pascal Launois;Ivan Maillard;Tilo Biedermann

  193
  Citations

• Exacerbation of murine cutaneous leishmaniasis by adoptive transfer of parasite-specific helper T cell populations capable of mediating Leishmania major-specific delayed-type hypersensitivity.

  R G Titus;G C Lima;H D Engers;J A Louis

  192
  Citations

• Immunology of leishmaniasis

  Richard M. Locksley;Jacques A. Louis;Jacques A. Louis

  179
  Citations

• Early production of IL-4 in susceptible mice infected with Leishmania major rapidly induces IL-12 unresponsiveness.

  P Launois;K G Swihart;G Milon;J A Louis

  179
  Citations

• Establishment of resistance to Leishmania major infection in susceptible BALB/c mice requires parasite-specific CD8+ T cells

  Ingrid Müller;Thierry Pedrazzini;Pascale Kropf;Jacques Louis

  167
  Citations

• Gamma interferon response in secondary Leishmania major infection: role of CD8+ T cells.

  I Müller;P Kropf;R J Etges;J A Louis

  166
  Citations