What is he best known for?
The fields of study he is best known for:
- Gene
- Immune system
- Cytokine
The scientist’s investigation covers issues in Tumor necrosis factor alpha, Immunology, Molecular biology, Cytokine and Cell biology.
His study in Tumor necrosis factor alpha is interdisciplinary in nature, drawing from both Necrosis, Pathology, Lung and Interferon gamma.
Pierre Vassalli has researched Immunology in several fields, including Lesion and Macrophage.
His Molecular biology research includes themes of Caspase 3, Caspase, Caspase 1 and Gene.
His studies in Cytokine integrate themes in fields like NFKB1, Cell nucleus, Protein subunit and Nuclear protein.
Pierre Vassalli interconnects Secretion, Exocytosis and Immunoglobulin secretion in the investigation of issues within Cell biology.
His most cited work include:
- The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection (1087 citations)
- Regulation of tumor necrosis factor alpha transcription in macrophages: involvement of four kappa B-like motifs and of constitutive and inducible forms of NF-kappa B. (814 citations)
- Tumor Necrosis Factor and Disease Severity in Children with Falciparum Malaria (748 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in Immunology, Molecular biology, Tumor necrosis factor alpha, Antigen and Antibody.
His study in Molecular biology is interdisciplinary in nature, drawing from both Spleen, Transplantation, Lymphocyte and Lymph.
His Tumor necrosis factor alpha study integrates concerns from other disciplines, such as Necrosis, Pathology and Cytokine.
Pierre Vassalli studied Antigen and Intestinal mucosa that intersect with Epithelium.
His Antibody study incorporates themes from Biochemistry, Cell type and Microfilament.
His work in T cell addresses issues such as Cytotoxic T cell, which are connected to fields such as Cell biology.
He most often published in these fields:
- Immunology (54.36%)
- Molecular biology (34.90%)
- Tumor necrosis factor alpha (27.52%)
What were the highlights of his more recent work (between 1994-2013)?
- Immunology (54.36%)
- Genetically modified mouse (8.05%)
- Transgene (8.05%)
In recent papers he was focusing on the following fields of study:
His primary areas of study are Immunology, Genetically modified mouse, Transgene, Tumor necrosis factor alpha and Molecular biology.
His work carried out in the field of Immunology brings together such families of science as Cytotoxic T cell and Cell biology.
His Genetically modified mouse research incorporates elements of Selectin, Cell adhesion molecule, Antigen and Pathology.
His biological study spans a wide range of topics, including Apoptosis and Expression vector.
His Tumor necrosis factor alpha study combines topics in areas such as Nitric oxide, Insulitis and Microbiology.
He combines subjects such as Delayed-Type Hypersensitivity Response, Messenger RNA, Untranslated region, Erythropoietin and Polymerase chain reaction with his study of Molecular biology.
Between 1994 and 2013, his most popular works were:
- An early and massive wave of germinal cell apoptosis is required for the development of functional spermatogenesis (516 citations)
- Expression of a tumor necrosis factor-alpha transgene in murine lung causes lymphocytic and fibrosing alveolitis. A mouse model of progressive pulmonary fibrosis (318 citations)
- Site-specific recombination of a transgene in fertilized eggs by transient expression of Cre recombinase (287 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Immune system
- Antibody
Pierre Vassalli mostly deals with Transgene, Molecular biology, Apoptosis, Genetically modified mouse and Tumor necrosis factor alpha.
His Molecular biology research is multidisciplinary, relying on both Cre recombinase, Fulminant, Gene and Expression vector.
His Apoptosis research includes themes of Receptor, Antibody, Intracellular and Stimulation.
The Genetically modified mouse study combines topics in areas such as Pulmonary pathology, Pulmonary fibrosis and Pathology.
His Tumor necrosis factor alpha research focuses on Lamina propria and how it connects with Immunology.
The various areas that Pierre Vassalli examines in his Immunology study include Necrosis, Cytotoxic T cell, Interleukin 12 and Spermatogenesis.
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