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Overview

James L.M. Ferrara is affiliated with the Icahn School of Medicine at Mount Sinai in the United States. Their research primarily focuses on medicine, with a significant emphasis on hematology, immunology, genetics, public health, and pediatrics. They have contributed extensively to the study of hematopoietic stem cell transplantation and related topics.

Ferrara's work covers several key areas:

  • Hematopoietic Stem Cell Transplantation
  • Acute Lymphoblastic Leukemia research
  • Childhood Cancer Survivors' Quality of Life
  • Immune Cell Function and Interaction
  • Mesenchymal stem cell research
  • Pancreatic and Hepatic Oncology Research
  • IL-33, ST2, and ILC Pathways

The scientist has published research in multiple venues, with frequent publications in:

  • Transplantation and Cellular Therapy
  • Blood
  • Blood Advances
  • Science Translational Medicine
  • Gastroenterology

Notable recent papers include:

  • "Phase II Trial of Costimulation Blockade With Abatacept for Prevention of Acute GVHD" (2021), Journal of Clinical Oncology
  • "Obesity induces gut microbiota alterations and augments acute graft-versus-host disease after allogeneic stem cell transplantation" (2020), Science Translational Medicine
  • "Effective treatment of low-risk acute GVHD with itacitinib monotherapy" (2022), Blood
  • "Incidence, clinical presentation, risk factors, outcomes, and biomarkers in de novo late acute GVHD" (2023), Blood Advances
  • "Biomarker-guided preemption of steroid-refractory graft-versus-host disease with α-1-antitrypsin" (2020), Blood Advances

Frequent collaborators in their research include:

  • John E. Levine
  • Aaron Etra
  • Hannah Choe
  • William J. Hogan
  • Elizabeth O. Hexner

Best Publications

  • Graft-versus-host disease

    James L M Ferrara;John E Levine;Pavan Reddy;Ernst Holler

  • Graft-versus-host disease

    J. L. M. Ferrara;H. J. Deeg

  • An experimental model of idiopathic pneumonia syndrome after bone marrow transplantation : I. The roles of minor H antigens and endotoxin

    Kenneth R. Cooke;Lester Kobzik;Thomas R. Martin;Joanne Brewer

  • Total body irradiation and acute graft-versus-host disease: The role of gastrointestinal damage and inflammatory cytokines

    Geoffrey R. Hill;Geoffrey R. Hill;James M. Crawford;James M. Crawford;Kenneth R. Cooke;Kenneth R. Cooke;Yani S. Brinson;Yani S. Brinson

  • The primacy of the gastrointestinal tract as a target organ of acute graft-versus-host disease: rationale for the use of cytokine shields in allogeneic bone marrow transplantation

    Geoffrey R. Hill;James L. M. Ferrara

  • Pretreatment of Donor Mice With Granulocyte Colony-Stimulating Factor Polarizes Donor T Lymphocytes Toward Type-2 Cytokine Production and Reduces Severity of Experimental Graft-Versus-Host Disease

    Luying Pan;John Delmonte;Candice K. Jalonen;James L.M. Ferrara

  • Induction of graft-versus-host disease as immunotherapy for relapsed chronic myeloid leukemia.

    David L. Porter;Mark S. Roth;Carol McGarigle;James Ferrara

  • International, Multicenter Standardization of Acute Graft-versus-Host Disease Clinical Data Collection: A Report from the Mount Sinai Acute GVHD International Consortium.

    Andrew C. Harris;Andrew C. Harris;Rachel Young;Rachel Young;Steven Devine;William J. Hogan

  • Acute graft-versus-host disease does not require alloantigen expression on host epithelium

    Takanori Teshima;Rainer Ordemann;Pavan Reddy;Svetlana Gagin

  • Metagenomic Analysis of the Stool Microbiome in Patients Receiving Allogeneic Stem Cell Transplantation: Loss of Diversity Is Associated with Use of Systemic Antibiotics and More Pronounced in Gastrointestinal Graft-versus-Host Disease

    Ernst Holler;Peter Butzhammer;Karin Schmid;Christian Hundsrucker

  • Blood and Marrow Transplant Clinical Trials Network Toxicity Committee consensus summary: Thrombotic microangiopathy after hematopoietic stem cell transplantation

    Vincent T. Ho;Corey Cutler;Shelly Carter;Paul Martin

  • Pathophysiologic mechanisms of acute graft-vs.-host disease

    James L.M. Ferrara;Robert Levy;Nelson J. Chao

  • A biomarker panel for acute graft-versus-host disease

    Sophie Paczesny;Sophie Paczesny;Oleg I Krijanovski;Thomas M Braun;Sung Won Choi

  • ST2 as a Marker for Risk of Therapy-Resistant Graft-versus-Host Disease and Death

    Mark T. Vander Lugt;Thomas M. Braun;Samir Hanash;Jerome Ritz

  • Recommended Screening and Preventive Practices for Long-term Survivors after Hematopoietic Cell Transplantation: Joint Recommendations of the European Group for Blood and Marrow Transplantation, the Center for International Blood and Marrow Transplant Research, and the American Society of Blood and Marrow Transplantation

    J. Douglas Rizzo;John R. Wingard;Andre Tichelli;Stephanie J. Lee

  • Tumor necrosis factor- alpha production to lipopolysaccharide stimulation by donor cells predicts the severity of experimental acute graft-versus-host disease.

    Kenneth R. Cooke;Geoffrey R. Hill;James M. Crawford;David Bungard

  • Regenerating islet-derived 3-alpha is a biomarker of gastrointestinal graft-versus-host disease

    James L.M. Ferrara;Andrew C. Harris;Joel K. Greenson;Thomas M. Braun

  • LPS antagonism reduces graft-versus-host disease and preserves graft-versus-leukemia activity after experimental bone marrow transplantation.

    Kenneth R. Cooke;Armin Gerbitz;James M. Crawford;Takanori Teshima

  • Interleukin-11 promotes T cell polarization and prevents acute graft-versus-host disease after allogeneic bone marrow transplantation.

    Geoffrey R. Hill;Kenneth R. Cooke;Takanori Teshima;James M. Crawford

  • EBMT-NIH-CIBMTR Task Force position statement on standardized terminology & guidance for graft-versus-host disease assessment.

    Helene M. Schoemans;Stephanie J. Lee;James L. Ferrara;Daniel Wolff

Frequent Co-Authors

John E. Levine
John E. Levine Icahn School of Medicine at Mount Sinai
Pavan Reddy
Pavan Reddy Baylor College of Medicine
Kenneth R. Cooke
Kenneth R. Cooke Johns Hopkins University School of Medicine
Sophie Paczesny
Sophie Paczesny Medical University of South Carolina
Takanori Teshima
Takanori Teshima Hokkaido University
Chen Liu
Chen Liu Yale University
Ernst Holler
Ernst Holler University of Regensburg
Geoffrey R. Hill
Geoffrey R. Hill Fred Hutchinson Cancer Research Center
Daniel J. Weisdorf
Daniel J. Weisdorf University of Minnesota
Vincent T. Ho
Vincent T. Ho Harvard University

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