His primary areas of study are Immunology, Leishmania donovani, Antigen, Spleen and Visceral leishmaniasis. His work in Immunity, Leishmaniasis, Immune system, Cytokine and T cell are all subfields of Immunology research. Leishmania donovani is a subfield of Leishmania that Paul M. Kaye tackles.
His Leishmania research incorporates elements of Macrophage, Monoclonal antibody, Intracellular parasite and Virology. His Antigen research is multidisciplinary, relying on both Tumor necrosis factor alpha, Leishmania infantum, Antibody and T cell immunology. The various areas that he examines in his Spleen study include Immunotherapy and Pathology.
Paul M. Kaye mainly focuses on Immunology, Leishmania donovani, Visceral leishmaniasis, Immune system and T cell. Paul M. Kaye frequently studies issues relating to Leishmania and Immunology. His work in Leishmania donovani covers topics such as Bone marrow which are related to areas like Haematopoiesis and Stromal cell.
As part of one scientific family, he deals mainly with the area of Visceral leishmaniasis, narrowing it down to issues related to the Interleukin 10, and often Interleukin 4. His T cell research includes elements of Molecular biology, Dendritic cell, CD8 and Cell biology. His research integrates issues of Leishmania major, Disease and Virology in his study of Leishmaniasis.
Paul M. Kaye mostly deals with Visceral leishmaniasis, Immunology, Immune system, Leishmaniasis and Leishmania donovani. His Visceral leishmaniasis study integrates concerns from other disciplines, such as Internal medicine, Clinical trial, BALB/c, Host and Vaccination. His specific area of interest is Immunology, where Paul M. Kaye studies Inflammation.
When carried out as part of a general Immune system research project, his work on Immunity is frequently linked to work in Context, therefore connecting diverse disciplines of study. Paul M. Kaye has researched Leishmaniasis in several fields, including Transmission, Virology, Environmental health and Disease. His Leishmania donovani research integrates issues from Zoology, Vector, Anemia and Bone marrow.
His primary scientific interests are in Immunology, Visceral leishmaniasis, Leishmania donovani, Immune system and Leishmaniasis. Particularly relevant to T cell is his body of work in Immunology. Paul M. Kaye interconnects Macrophage, Disease and Leishmania in the investigation of issues within Visceral leishmaniasis.
His Leishmania donovani research is multidisciplinary, incorporating elements of Haematopoiesis and Bone marrow. His Immune system study incorporates themes from Spleen, Immunopathology and Vaccination. His Leishmaniasis research focuses on subjects like Virology, which are linked to Gene, Microbiology, Antigen and Pathogen.
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Leishmaniasis: complexity at the host–pathogen interface
Paul Kaye;Phillip Scott.
Nature Reviews Microbiology (2011)
The role of dendritic cells in the induction and regulation of immunity to microbial infection.
Caetano Reis e Sousa;Alan Sher;Paul Kaye.
Current Opinion in Immunology (1999)
Leishmaniasis: new approaches to disease control
Clive R Davies;Paul Kaye;Simon L Croft;Shyam Sundar.
DENDRITIC CELLS, BUT NOT MACROPHAGES, PRODUCE IL-12 IMMEDIATELY FOLLOWING LEISHMANIA DONOVANI INFECTION
Patricia M. A. Gorak;Christian R. Engwerda;Paul M. Kaye.
European Journal of Immunology (1998)
Locally Up-regulated Lymphotoxin α, Not Systemic Tumor Necrosis Factor α, Is the Principle Mediator of Murine Cerebral Malaria
Christian R. Engwerda;Tracey L. Mynott;Sanjeet Sawhney;J. Brian De Souza.
Journal of Experimental Medicine (2002)
Differential production of Th1- and Th2-derived cytokines does not determine the genetically controlled or vaccine-induced rate of cure in murine visceral leishmaniasis.
P M Kaye;A J Curry;J M Blackwell.
Journal of Immunology (1991)
The immunopathology of experimental visceral leishmaniasis
Paul M. Kaye;Mattias Svensson;Manabu Ato;Asher Maroof.
Immunological Reviews (2004)
Stromal Cells Direct Local Differentiation of Regulatory Dendritic Cells
Mattias Svensson;Asher Maroof;Manabu Ato;Paul M. Kaye.
B Cell-Deficient Mice Are Highly Resistant to Leishmania donovani Infection, but Develop Neutrophil-Mediated Tissue Pathology
Sara C. Smelt;Sara E. J. Cotterell;Christian R. Engwerda;Paul M. Kaye.
Journal of Immunology (2000)
Natural antibodies and complement are endogenous adjuvants for vaccine-induced CD8+ T-cell responses.
Simona Stäger;James Alexander;Alun C Kirby;Marina Botto.
Nature Medicine (2003)
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