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D-Index & Metrics

Biology and Biochemistry

D-Index
69
Citations
18038
World Ranking
7346
National Ranking
536

Overview

Arne Skerra is affiliated with the Technical University of Munich in Germany. Their research spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on various subfields including Molecular Biology, Radiology, Nuclear Medicine and Imaging, Immunology, Surgery, and Oncology.

The scientist's work prominently addresses topics such as Monoclonal and Polyclonal Antibodies Research, Pesticide and Herbicide Environmental Studies, Protein purification and stability, Xenotransplantation and immune response, Pesticide Exposure and Toxicity, Amino Acid Enzymes and Metabolism, and Peptidase Inhibition and Analysis.

Recent publications authored or co-authored include:

  • Engineered Protein Scaffolds as Next-Generation Therapeutics, 2020, The Annual Review of Pharmacology and Toxicology
  • Complement inhibition at the level of C3 or C5: mechanistic reasons for ongoing terminal pathway activity, 2020, Blood
  • The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma, 2021, Molecular Cell
  • Hsp70 in Liquid Biopsies-A Tumor-Specific Biomarker for Detection and Response Monitoring in Cancer, 2021, Cancers
  • Anticalin® proteins: from bench to bedside, 2020, Expert Opinion on Biological Therapy

Frequent co-authors include:

  • A. Eichinger
  • Volker Morath
  • Wolfgang Weber
  • Uli Binder
  • Martin Schlapschy

Arne Skerra has published multiple articles in journals such as ChemBioChem, Scientific Reports, Expert Opinion on Biological Therapy, Nature Communications, and the Journal of Molecular Biology. The number of publications in these venues varies, with ChemBioChem hosting the highest count of five papers.

Best Publications

  • The Strep -tag system for one-step purification and high-affinity detection or capturing of proteins

    Thomas G M Schmidt;Arne Skerra

  • Crucial role for human Toll-like receptor 4 in the development of contact allergy to nickel

    Marc Schmidt;Badrinarayanan Raghavan;Badrinarayanan Raghavan;Verena Müller;Verena Müller;Thomas Vogl

  • Engineered protein scaffolds as next-generation antibody therapeutics

    Michaela Gebauer;Arne Skerra

  • Alternative non-antibody scaffolds for molecular recognition.

    Arne Skerra

  • Engineered protein scaffolds for molecular recognition.

    Arne Skerra

  • Consistent success in life-supporting porcine cardiac xenotransplantation

    Matthias Längin;Tanja Mayr;Bruno Reichart;Sebastian Michel

  • PASylation: a biological alternative to PEGylation for extending the plasma half-life of pharmaceutically active proteins

    Martin Schlapschy;Uli Binder;Claudia Börger;Ina Theobald

  • Lipocalins as a scaffold.

    Arne Skerra

  • Regeneration of Lesioned Corticospinal Tract Fibers in the Adult Rat Induced by a Recombinant, Humanized IN-1 Antibody Fragment

    Christian Brösamle;Andrea B. Huber;Markus Fiedler;Arne Skerra

  • Interferon-γ Regulates Intestinal Epithelial Homeostasis through Converging β-Catenin Signaling Pathways

    Porfirio Nava;Stefan Koch;Mike G. Laukoetter;Mike G. Laukoetter;Winston Y. Lee

  • The crystal structure of the human (S100A8/S100A9)2 heterotetramer, calprotectin, illustrates how conformational changes of interacting alpha-helices can determine specific association of two EF-hand proteins

    Ingo P. Korndörfer;Florian Brueckner;Arne Skerra

  • Use of the Strep-Tag and streptavidin for detection and purification of recombinant proteins.

    Arne Skerra;Thomas G.M. Schmidt

  • Alternative binding proteins: anticalins - harnessing the structural plasticity of the lipocalin ligand pocket to engineer novel binding activities.

    Arne Skerra

  • Binding proteins from alternative scaffolds.

    Per-Åke Nygren;Arne Skerra

  • Expression of functional antibody Fv and Fab fragments in Escherichia coli.

    Andreas Plückthun;Arne Skerra

  • ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome

    Michael J. Taussig;Oda Stoevesandt;Carl A. K. Carl A K Borrebaeck;Andrew R. Bradbury

  • Application of neutralizing antibodies against NI-35/250 myelin-associated neurite growth inhibitory proteins to the adult rat cerebellum induces sprouting of uninjured purkinje cell axons.

    Annalisa Buffo;Marta Zagrebelsky;Andrea B. Huber;Arne Skerra

  • Lipocalins in drug discovery: from natural ligand-binding proteins to "anticalins".

    Steffen Schlehuber;Arne Skerra

  • "muteínas da lipocalina associada à gelatinase de neutrófilos humanos, proteínas relacionadas, composição farmacêutica, método para geração e uso das mesmas".

    Arne Skerra;Steffen Schlehuber

  • Targeting membrane heat-shock protein 70 (Hsp70) on tumors by cmHsp70.1 antibody

    Stefan Stangl;Mathias Gehrmann;Julia Riegger;Kristin Kuhs

Frequent Co-Authors

Andreas Plückthun
Andreas Plückthun University of Zurich
Markus Schwaiger
Markus Schwaiger Technical University of Munich
Wolfgang A. Weber
Wolfgang A. Weber Technical University of Munich
Hubert Schrezenmeier
Hubert Schrezenmeier University of Ulm
Bernhard Kuster
Bernhard Kuster Technical University of Munich
Gideon Schreiber
Gideon Schreiber Weizmann Institute of Science
Thomas Szyperski
Thomas Szyperski University at Buffalo, State University of New York
Hans-Jürgen Wester
Hans-Jürgen Wester Technical University of Munich
Kirsten Jung
Kirsten Jung Ludwig-Maximilians-Universität München
Siegfried Scherer
Siegfried Scherer Technical University of Munich

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