World's Best Scientists 2026 revealed!
Elizabeth M. Nolan

Elizabeth M. Nolan

D-Index & Metrics

Chemistry

D-Index
48
Citations
13086
World Ranking
15052
National Ranking
3836

Research.com Recognitions

  • 2013 - Fellow of Alfred P. Sloan Foundation

Overview

Elizabeth M. Nolan is affiliated with MIT in the United States, specializing primarily in the field of Biochemistry, Genetics and Molecular Biology. Their research output includes 53 publications within this broad discipline, with focused subfields encompassing Molecular Biology, Nutrition and Dietetics, Molecular Medicine, Endocrinology, and Infectious Diseases.

Their work addresses multiple scientific topics, notably:

  • S100 Proteins and Annexins
  • Antibiotic Resistance in Bacteria
  • Trace Elements in Health
  • Bacterial biofilms and quorum sensing
  • Escherichia coli research studies
  • Immune Response and Inflammation
  • Bacterial Genetics and Biotechnology

Elizabeth M. Nolan has contributed to several journals frequently, including:

  • Journal of the American Chemical Society
  • Biochemistry
  • ACS Infectious Diseases
  • bioRxiv (Cold Spring Harbor Laboratory)
  • mBio

Some of the recent papers authored or coauthored by Nolan are:

  • Heavy-Metal Trojan Horse: Enterobactin-Directed Delivery of Platinum(IV) Prodrugs to Escherichia coli, 2022, Journal of the American Chemical Society
  • Heme protects Pseudomonas aeruginosa and Staphylococcus aureus from calprotectin-induced iron starvation, 2020, Journal of Biological Chemistry
  • Enterobactin- and salmochelin-β-lactam conjugates induce cell morphologies consistent with inhibition of penicillin-binding proteins in uropathogenic Escherichia coli CFT073, 2021, Chemical Science
  • Metal Sequestration and Antimicrobial Activity of Human Calprotectin Are pH-Dependent, 2020, Biochemistry
  • Harnessing Iron Acquisition Machinery to Target Enterobacteriaceae, 2020, The Journal of Infectious Diseases

Frequent collaborators who have coauthored papers with Nolan include:

  • Amanda G. Oglesby (8 collaborations)
  • Artur Sargun (7 collaborations)
  • Manuela Raffatellu (7 collaborations)
  • Chuchu Guo (5 collaborations)
  • Emily M. Zygiel (5 collaborations)

Throughout their research career, Nolan's work has intersected with key areas in metal biology and microbial pathogenesis, especially relating to bacterial iron acquisition and host-pathogen interactions. Among awards received, Nolan was named Fellow of the Alfred P. Sloan Foundation in 2013.

Best Publications

  • Tools and tactics for the optical detection of mercuric ion.

    Elizabeth M Nolan;Stephen J Lippard

  • A "turn-on" fluorescent sensor for the selective detection of mercuric ion in aqueous media.

    Elizabeth M Nolan;Stephen J Lippard

  • Small-molecule fluorescent sensors for investigating zinc metalloneurochemistry.

    Elizabeth M. Nolan;Stephen J. Lippard

  • Turn-On and Ratiometric Mercury Sensing in Water with a Red-Emitting Probe

    Elizabeth M. Nolan;Stephen J. Lippard

  • Beyond iron: non-classical biological functions of bacterial siderophores

    Timothy C. Johnstone;Elizabeth M. Nolan

  • Zinspy sensors with enhanced dynamic range for imaging neuronal cell zinc uptake and mobilization.

    Elizabeth M. Nolan;Jubin W. Ryu;Jacek Jaworski;Rodney P. Feazell

  • A tautomeric zinc sensor for ratiometric fluorescence imaging: application to nitric oxide-induced release of intracellular zinc.

    Christopher J. Chang;Jacek Jaworski;Elizabeth M. Nolan;Morgan Sheng

  • Human calprotectin is an iron-sequestering host-defense protein

    Toshiki G Nakashige;Bo Zhang;Carsten Krebs;Elizabeth M Nolan

  • QZ1 and QZ2: rapid, reversible quinoline-derivatized fluoresceins for sensing biological Zn(II).

    Elizabeth M. Nolan;Jacek Jaworski;Ken-Ichi Okamoto;Yasunori Hayashi

  • Selective Hg(II) detection in aqueous solution with thiol derivatized fluoresceins.

    Elizabeth M. Nolan;Maryann E. Racine;Stephen J. Lippard

  • Organelle-specific zinc detection using zinpyr-labeled fusion proteins in live cells.

    Elisa Tomat;Elizabeth M. Nolan;Jacek Jaworski;Stephen J. Lippard

  • Transition Metal Sequestration by the Host-Defense Protein Calprotectin

    Emily M. Zygiel;Elizabeth M. Nolan

  • Membrane anchoring stabilizes and favors secretion of New Delhi metallo-β-lactamase.

    Lisandro J González;Lisandro J González;Guillermo Bahr;Guillermo Bahr;Toshiki G Nakashige;Elizabeth M Nolan

  • Enterobactin-Mediated Delivery of β-Lactam Antibiotics Enhances Antibacterial Activity against Pathogenic Escherichia coli

    Tengfei Zheng;Elizabeth M. Nolan

  • Bright Fluorescent Chemosensor Platforms for Imaging Endogenous Pools of Neuronal Zinc

    Christopher J Chang;Elizabeth M Nolan;Jacek Jaworski;Shawn C Burdette

  • Calcium Ion Gradients Modulate the Zinc Affinity and Antibacterial Activity of Human Calprotectin

    Megan Brunjes Brophy;Joshua A. Hayden;Elizabeth M. Nolan

  • Synthesis and characterization of zinc sensors based on a monosubstituted fluorescein platform.

    Elizabeth M Nolan;Shawn C Burdette;Jessica H Harvey;Scott A Hilderbrand

  • Esterase-Catalyzed Siderophore Hydrolysis Activates an Enterobactin-Ciprofloxacin Conjugate and Confers Targeted Antibacterial Activity.

    Wilma Neumann;Martina Sassone-Corsi;Manuela Raffatellu;Elizabeth M. Nolan

  • Siderophore-Mediated Cargo Delivery to the Cytoplasm of Escherichia coli and Pseudomonas aeruginosa: Syntheses of Monofunctionalized Enterobactin Scaffolds and Evaluation of Enterobactin–Cargo Conjugate Uptake

    Tengfei Zheng;Justin L Bullock;Elizabeth M Nolan

  • ZP8, a neuronal zinc sensor with improved dynamic range; imaging zinc in hippocampal slices with two-photon microscopy.

    Christopher J. Chang;Elizabeth M. Nolan;Jacek Jaworski;Ken-Ichi Okamoto

  • MS4, a seminaphthofluorescein-based chemosensor for the ratiometric detection of Hg(II)

    Elizabeth M. Nolan;Stephen J. Lippard

  • The Zinspy Family of Fluorescent Zinc Sensors: Syntheses and Spectroscopic Investigations

    Elizabeth M. Nolan;Stephen J. Lippard

Frequent Co-Authors

Christopher T. Walsh
Christopher T. Walsh Stanford University
Manuela Raffatellu
Manuela Raffatellu University of California, San Diego
Morgan Sheng
Morgan Sheng Broad Institute
Gerhard Wagner
Gerhard Wagner Harvard University
R. David Britt
R. David Britt University of California, Davis
Christopher J. Chang
Christopher J. Chang Princeton University
Robert A. Bonomo
Robert A. Bonomo Case Western Reserve University

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