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Christopher J. Chang

Christopher J. Chang

D-Index & Metrics

Chemistry

D-Index
125
Citations
58771
World Ranking
401
National Ranking
174

Research.com Recognitions

  • 2017 - Fellow of the American Academy of Arts and Sciences
  • 2008 - Hellman Fellow
  • 2007 - Fellow of Alfred P. Sloan Foundation

Overview

Christopher J. Chang is affiliated with Princeton University in the United States. Their research primarily focuses on the intersection of biochemistry, genetics, and molecular biology, with a strong emphasis on molecular biology. Their work also extensively involves materials chemistry, nutrition and dietetics, renewable energy, sustainability, the environment, and spectroscopy.

Chang's research topics cover a range of areas including trace elements in health, molecular sensors and ion detection, CO2 reduction techniques and catalysts, crystallization and solubility studies, X-ray diffraction in crystallography, drug transport and resistance mechanisms, and metal-organic frameworks synthesis and applications.

Several recent publications illustrate the scope of their research. In 2021, they contributed to the paper titled "Connecting copper and cancer: from transition metal signalling to metalloplasia" published in Nature Reviews Cancer. In 2022, they were involved in "Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo" featured in Nature Metabolism. In 2020, Chang contributed to two papers: "MDM2 and MDMX promote ferroptosis by PPARα-mediated lipid remodeling" in Genes & Development and "Bioinspiration in light harvesting and catalysis" published in Nature Reviews Materials. Another 2020 publication is "Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis" in Nature Communications.

Frequent collaborators include Aidan T. Pezacki, Peter T. Smith, Matthias Loipersberger, Martin Head-Gordon, and Jeffrey S. Derrick. These coauthors have contributed significantly to Chang's body of work, reflecting a collaborative research environment.

Chang has published extensively across several prominent scientific venues. Notable publication venues include The Cambridge Structural Database, the Journal of the American Chemical Society, bioRxiv (Cold Spring Harbor Laboratory), Proceedings of the National Academy of Sciences, and Angewandte Chemie International Edition. This diversity of publication outlets demonstrates a breadth of engagement with both chemistry and biology-focused research audiences.

Their achievements include recognition as a Fellow of the American Academy of Arts and Sciences in 2017, designation as a Hellman Fellow in 2008, and fellowship with the Alfred P. Sloan Foundation in 2007.

Best Publications

  • Covalent organic frameworks comprising cobalt porphyrins for catalytic CO2 reduction in water

    Song-Chow Lin;Song-Chow Lin;Christian S Diercks;Christian S Diercks;Yue-Biao Zhang;Yue-Biao Zhang;Yue-Biao Zhang;Nikolay Kornienko

  • Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging

    Emily L. Que;Dylan W. Domaille;Christopher J. Chang

  • Chemistry and biology of reactive oxygen species in signaling or stress responses

    Bryan C Dickinson;Christopher J Chang

  • Reaction-based small-molecule fluorescent probes for chemoselective bioimaging

    Jefferson Chan;Sheel C. Dodani;Christopher J. Chang

  • A Molecular MoS2 Edge Site Mimic for Catalytic Hydrogen Generation

    Hemamala I. Karunadasa;Hemamala I. Karunadasa;Elizabeth Montalvo;Yujie Sun;Yujie Sun;Marcin Majda

  • Synthetic fluorescent sensors for studying the cell biology of metals

    Dylan W Domaille;Emily L Que;Christopher J Chang

  • Connecting copper and cancer: from transition metal signalling to metalloplasia.

    Eva J Ge;Ashley I Bush;Angela Casini;Paul A Cobine

  • Metal−Organic Frameworks for Electrocatalytic Reduction of Carbon Dioxide

    Nikolay Kornienko;Yingbo Zhao;Christopher S. Kley;Chenhui Zhu

  • Chemical probes for molecular imaging and detection of hydrogen sulfide and reactive sulfur species in biological systems

    Vivian S. Lin;Wei Chen;Ming Xian;Christopher J. Chang

  • A Selective Turn-On Fluorescent Sensor for Imaging Copper in Living Cells

    Li Zeng;Evan W Miller;Arnd Pralle;Ehud Y Isacoff

  • Unraveling the biological roles of reactive oxygen species.

    Michael P. Murphy;Arne Holmgren;Nils Göran Larsson;Barry Halliwell

  • Boronate Oxidation as a Bioorthogonal Reaction Approach for Studying the Chemistry of Hydrogen Peroxide in Living Systems

    Alexander R. Lippert;Genevieve C. Van de Bittner;Christopher J. Chang

  • Reaction-based fluorescent probes for selective imaging of hydrogen sulfide in living cells.

    Alexander R. Lippert;Elizabeth J. New;Christopher J. Chang

  • Aquaporin-3 mediates hydrogen peroxide uptake to regulate downstream intracellular signaling

    Evan W. Miller;Bryan C. Dickinson;Christopher J. Chang

  • A molecular molybdenum-oxo catalyst for generating hydrogen from water

    Hemamala I. Karunadasa;Christopher J. Chang;Christopher J. Chang;Jeffrey R. Long;Jeffrey R. Long

  • A selective, cell-permeable optical probe for hydrogen peroxide in living cells.

    Michelle C. Y. Chang;Arnd Pralle;Ehud Y. Isacoff;Christopher J. Chang

  • Screening Mercury Levels in Fish with a Selective Fluorescent Chemosensor

    Sungho Yoon;Aaron E. Albers;and Audrey P. Wong;Christopher J. Chang

  • Complexes of earth-abundant metals for catalytic electrochemical hydrogen generation under aqueous conditions

    V. Sara Thoi;V. Sara Thoi;Yujie Sun;Yujie Sun;Jeffrey R. Long;Jeffrey R. Long;Christopher J. Chang;Christopher J. Chang

  • A Targetable Fluorescent Probe for Imaging Hydrogen Peroxide in the Mitochondria of Living Cells

    Bryan C. Dickinson;Christopher J. Chang

  • Boronate-Based Fluorescent Probes for Imaging Cellular Hydrogen Peroxide

    Evan W Miller;Aaron E Albers;Arnd Pralle;Ehud Y Isacoff

  • Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging (Published on the Web April 22, 2008.)

    Emily L. Que;Dylan W. Domaille;Christopher J. Chang

Frequent Co-Authors

Jeffrey R. Long
Jeffrey R. Long Lawrence Berkeley National Laboratory
Daniel G. Nocera
Daniel G. Nocera Harvard University
Jefferson Y. Chan
Jefferson Y. Chan University of Illinois at Urbana-Champaign
Martin Head-Gordon
Martin Head-Gordon University of California, Berkeley
Yujie Sun
Yujie Sun University of Cincinnati
F. Dean Toste
F. Dean Toste University of California, Berkeley
Peidong Yang
Peidong Yang University of California, Berkeley
Hemamala I. Karunadasa
Hemamala I. Karunadasa Stanford University
Ehud Y. Isacoff
Ehud Y. Isacoff University of California, Berkeley
Gary J. Long
Gary J. Long Missouri University of Science and Technology

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