Deborah F. Smith

Overview

Best Publications

• The genome of the kinetoplastid parasite, Leishmania major.

  Alasdair C. Ivens;Christopher S. Peacock;Elizabeth A. Worthey;Lee Murphy

  1753
  Citations

• TriTrypDB: a functional genomic resource for the Trypanosomatidae

  Martin Aslett;Cristina Aurrecoechea;Matthew Berriman;John Brestelli

  1130
  Citations

• Comparative genomic analysis of three Leishmania species that cause diverse human disease

  Christopher S Peacock;Kathy Seeger;David Harris;Lee Murphy

  941
  Citations

• Immunological modulation and evasion by helminth parasites in human populations

  Rick M. Maizels;Don A. P. Bundy;Murray E. Selkirk;Deborah F. Smith

  690
  Citations

• Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania

  Matthew B. Rogers;James D. Hilley;Nicholas J. Dickens;Jon Wilkes

  531
  Citations

• N-Myristoyltransferase Inhibitors as New Leads to Treat Sleeping Sickness.

  Julie A. Frearson;Stephen Brand;Stuart P. McElroy;Laura A.T. Cleghorn

  350
  Citations

• Toll-Like Receptor 4 Contributes to Efficient Control of Infection with the Protozoan Parasite Leishmania major

  Pascale Kropf;Marina A. Freudenberg;Manuel Modolell;Helen P. Price

  324
  Citations

• Vitellogenesis: a versatile model for hormonal regulation of gene expression.

  J.R. Tata;D.F. Smith

  318
  Citations

• GeneDB—an annotation database for pathogens

  Flora J. Logan-Klumpler;Nishadi De Silva;Ulrike Boehme;Matthew B Rogers

  281
  Citations

• Natural antibodies and complement are endogenous adjuvants for vaccine-induced CD8+ T-cell responses.

  Simona Stäger;James Alexander;Alun C Kirby;Marina Botto

  258
  Citations

• Immunization with a Recombinant Stage-Regulated Surface Protein from Leishmania donovani Induces Protection Against Visceral Leishmaniasis

  Simona Stäger;Deborah F. Smith;Paul M. Kaye

  250
  Citations

• Acylation-dependent protein export in Leishmania.

  Paul W. Denny;Suzanne Gokool;David G. Russell;Mark C. Field

  216
  Citations

• Myristoyl-CoA:Protein N-Myristoyltransferase, an Essential Enzyme and Potential Drug Target in Kinetoplastid Parasites

  Helen P. Price;Malini R. Menon;Chrysoula Panethymitaki;David Goulding

  214
  Citations

• Genomic Confirmation of Hybridisation and Recent Inbreeding in a Vector-Isolated Leishmania Population

  Matthew B. Rogers;Tim Downing;Barbara A. Smith;Hideo Imamura

  187
  Citations

• Hybridization in Parasites: Consequences for Adaptive Evolution, Pathogenesis, and Public Health in a Changing World.

  Kayla C. King;Rike B. Stelkens;Joanne P. Webster;Deborah F. Smith

  184
  Citations

• Protein farnesyl and N-myristoyl transferases: piggy-back medicinal chemistry targets for the development of antitrypanosomatid and antimalarial therapeutics

  Michael H. Gelb;Wesley C. Van Voorhis;Frederick S. Buckner;Kohei Yokoyama

  179
  Citations

• Comparative genomics: from genotype to disease phenotype in the leishmaniases.

  Deborah F. Smith;Christopher S. Peacock;Angela K. Cruz

  171
  Citations

• A third generation vaccine for human visceral leishmaniasis and post kala azar dermal leishmaniasis: First-in-human trial of ChAd63-KH

  Mohamed Osman;Anoop Mistry;Ada Keding;Rhian Gabe

  153
  Citations

• Dynamic imaging of experimental Leishmania donovani-induced hepatic granulomas detects Kupffer cell-restricted antigen presentation to antigen-specific CD8 T cells.

  Lynette Beattie;Adam Peltan;Asher Maroof;Alun Kirby

  147
  Citations

• Proteomic analysis of Leishmania mexicana differentiation.

  Philip G. Nugent;Saiful A. Karsani;Robin Wait;Jane Tempero

  137
  Citations