World's Best Scientists 2026 revealed!
Anthony J. Wilkinson

Anthony J. Wilkinson

D-Index & Metrics

Chemistry

D-Index
71
Citations
17660
World Ranking
5563
National Ranking
322

Biology and Biochemistry

D-Index
73
Citations
19682
World Ranking
5916
National Ranking
457

Overview

Anthony J. Wilkinson is affiliated with the University of York in the United Kingdom. Their research spans multiple areas including Medicine and Biochemistry, Genetics and Molecular Biology, reflecting a multidisciplinary focus on both human health and molecular processes.

They have contributed extensively to subfields such as Molecular Biology, Epidemiology, Public Health, Environmental and Occupational Health, Oncology, and Infectious Diseases. This broad range indicates involvement in both fundamental biological studies and applied health sciences.

The primary topics of Wilkinson's work include:

  • Trypanosoma species research and implications
  • Research on Leishmaniasis Studies
  • Biochemical and Molecular Research
  • Drug Transport and Resistance Mechanisms
  • Bacterial Genetics and Biotechnology
  • Ubiquitin and proteasome pathways
  • Protein Degradation and Inhibitors

Frequent co-authors in Wilkinson's publications reflect ongoing collaborative research efforts. These co-authors include:

  • Jeremy C. Mottram
  • Gavin H. Thomas
  • Reyme Herman
  • E.J. Dodson
  • Rebecca J. Burge

Wilkinson's recent papers demonstrate a focus on parasitic diseases, molecular mechanisms, and biochemical pathways. Selected recent works include:

  • "Leishmania differentiation requires ubiquitin conjugation mediated by a UBC2-UEV1 E2 complex" (2020, PLoS Pathogens)
  • "The molecular basis of thioalcohol production in human body odour" (2020, Scientific Reports)
  • "EARLY FLOWERING3 sub-nuclear localization responds to changes in ambient temperature" (2021, PLANT PHYSIOLOGY)
  • "Novel Thienopyrimidine Inhibitors of Leishmania N-Myristoyltransferase with On-Target Activity in Intracellular Amastigotes" (2020, Journal of Medicinal Chemistry)
  • "Peptide transport in Bacillus subtilis - structure and specificity in the extracellular solute binding proteins OppA and DppE" (2022, Microbiology)

The publication venues where Wilkinson frequently contributes include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Microbiology
  • Journal of Biological Chemistry
  • Biochemical Journal
  • PLoS Pathogens

Best Publications

  • AAA+ superfamily ATPases: common structure--diverse function.

    Teru Ogura;Anthony J. Wilkinson

  • Hydrogen bonding and biological specificity analysed by protein engineering

    Alan R. Fersht;Jian-Ping Shi;Jack Knill-Jones;Denise M. Lowe

  • Condition-Dependent Transcriptome Reveals High-Level Regulatory Architecture in Bacillus subtilis

    Pierre Nicolas;Ulrike Mäder;Etienne Dervyn;Tatiana Rochat

  • THE STEREOCHEMICAL MECHANISM OF THE COOPERATIVE EFFECTS IN HEMOGLOBIN REVISITED

    M. F. Perutz;A. J. Wilkinson;M. Paoli;G. G. Dodson

  • The use of double mutants to detect structural changes in the active site of the tyrosyl-tRNA synthetase (Bacillus stearothermophilus)

    Paul J. Carter;Greg Winter;Anthony J. Wilkinson;Alan R. Fersht

  • The mechanism of autooxidation of myoglobin.

    R E Brantley;S J Smerdon;A J Wilkinson;E W Singleton

  • Redesigning enzyme structure by site-directed mutagenesis: tyrosyl tRNA synthetase and ATP binding

    Greg Winter;Alan R. Fersht;Anthony J. Wilkinson;Mark Zoller

  • Computer Simulation of Biomolecular Systems

    Wilfred F. van Gunsteren;Paul K. Weiner;Anthony J. Wilkinson

  • The solution structure of human epidermal growth factor

    Robert M. Cooke;Anthony J. Wilkinson;Martin Baron;Annalisa Pastore

  • Site-directed mutagenesis as a probe of enzyme structure and catalysis: tyrosyl-tRNA synthetase cysteine-35 to glycine-35 mutation.

    Anthony J. Wilkinson;Alan R. Fersht;David M. Blow;Greg Winter

  • N-Myristoyltransferase Inhibitors as New Leads to Treat Sleeping Sickness.

    Julie A. Frearson;Stephen Brand;Stuart P. McElroy;Laura A.T. Cleghorn

  • Conserved arginine residues implicated in ATP hydrolysis, nucleotide-sensing, and inter-subunit interactions in AAA and AAA+ ATPases

    Teru Ogura;Sidney W Whiteheart;Anthony J Wilkinson

  • Global Network Reorganization During Dynamic Adaptations of Bacillus subtilis Metabolism

    Joerg Martin Buescher;Wolfram Liebermeister;Matthieu Jules;Markus Uhr

  • The structural basis of sequence-independent peptide binding by OppA protein

    Jeremy R. H. Tame;Garib N. Murshudov;Eleanor J. Dodson;Teresa K. Neil

  • Dissecting the role of a conserved motif (the second region of homology) in the AAA family of ATPases. Site-directed mutagenesis of the ATP-dependent protease FtsH.

    Kiyonobu Karata;Takabumi Inagawa;Anthony J. Wilkinson;Takashi Tatsuta

  • Global profiling of co- and post-translationally N -myristoylated proteomes in human cells

    Emmanuelle Thinon;Remigiusz A. Serwa;Malgorzata Broncel;James A. Brannigan

  • Crystal structure of T state haemoglobin with oxygen bound at all four haems.

    Massimo Paoli;Robert Liddington;Jeremy Tame;Anthony Wilkinson

  • Validation of N -myristoyltransferase as an antimalarial drug target using an integrated chemical biology approach

    Megan H. Wright;Barbara Clough;Mark D. Rackham;Kaveri Rangachari

  • Crystallographic and calorimetric analysis of peptide binding to OppA protein.

    S.H. Sleigh;P.R. Seavers;A.J. Wilkinson;J.E. Ladbury

  • Protein engineering 20 years on.

    James A. Brannigan;Anthony J. Wilkinson

  • A large increase in enzyme–substrate affinity by protein engineering

    Anthony J. Wilkinson;Alan R. Fersht;D. M. Blow;Paul Carter

Frequent Co-Authors

Keith S. Wilson
Keith S. Wilson University of York
Eleanor J. Dodson
Eleanor J. Dodson University of York
Richard J. Lewis
Richard J. Lewis University of Queensland
Edward W. Tate
Edward W. Tate Imperial College London
Robin J. Leatherbarrow
Robin J. Leatherbarrow Imperial College London
Stephen J. Smerdon
Stephen J. Smerdon University of Birmingham
Jeremy R. H. Tame
Jeremy R. H. Tame Yokohama City University
Greg Winter
Greg Winter University of Cambridge
Guy Dodson
Guy Dodson University of York

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