Stephen J. Smerdon

Research.com Recognitions

• Member of the European Molecular Biology Organization (EMBO)
• Member of the European Molecular Biology Organization (EMBO)
• Member of the European Molecular Biology Organization (EMBO)

Overview

Best Publications

• The structural basis for 14-3-3:phosphopeptide binding specificity.

  Michael B Yaffe;Katrin Rittinger;Stefano Volinia;Paul R Caron

  1998
  Citations

• MDC1 Directly Binds Phosphorylated Histone H2AX to Regulate Cellular Responses to DNA Double-Strand Breaks

  Manuel Stucki;Julie A. Clapperton;Duaa Mohammad;Michael B. Yaffe

  1356
  Citations

• The ankyrin repeat: a diversity of interactions on a common structural framework.

  Steven G Sedgwick;Stephen J Smerdon

  1051
  Citations

• The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain.

  Andrew E.H. Elia;Peter Rellos;Lesley F. Haire;Jerry W. Chao

  894
  Citations

• Structural Analysis of 14-3-3 Phosphopeptide Complexes Identifies a Dual Role for the Nuclear Export Signal of 14-3-3 in Ligand Binding

  Katrin Rittinger;Joe Budman;Jian Xu;Stefano Volinia

  620
  Citations

• Structure of a 14-3-3 protein and implications for coordination of multiple signalling pathways

  Bing Xiao;Stephen J. Smerdon;David H. Jones;Guy G. Dodson;Guy G. Dodson

  614
  Citations

• The Molecular Basis of FHA Domain:Phosphopeptide Binding Specificity and Implications for Phospho-Dependent Signaling Mechanisms

  Daniel Durocher;Ian A. Taylor;Dilara Sarbassova;Lesley F. Haire

  551
  Citations

• Structure at 1.65 Å of RhoA and its GTPase-activating protein in complex with a transition-state analogue

  Katrin Rittinger;Philip A. Walker;John F. Eccleston;Stephen J. Smerdon

  543
  Citations

• The mechanism of autooxidation of myoglobin.

  R E Brantley;S J Smerdon;A J Wilkinson;E W Singleton

  503
  Citations

• Molecular basis of phosphorylation-induced activation of the NADPH oxidase.

  Yvonne Groemping;Karine Lapouge;Stephen J. Smerdon;Katrin Rittinger

  477
  Citations

• Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1

  S J Smerdon;J Jäger;J Wang;L A Kohlstaedt

  454
  Citations

• A unified polymerase mechanism for nonhomologous DNA and RNA polymerases

  TA Steitz;SJ Smerdon;J Jager;CM Joyce

  402
  Citations

• Structure of the TPR domain of p67phox in complex with Rac.GTP.

  Karine Lapouge;Susan J.M Smith;Philip A Walker;Steven J Gamblin

  397
  Citations

• Structural determinants of 14-3-3 binding specificities and regulation of subcellular localization of 14-3-3-ligand complexes: a comparison of the X-ray crystal structures of all human 14-3-3 isoforms.

  Alexandra K. Gardino;Stephen J. Smerdon;Michael B. Yaffe

  386
  Citations

• Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP

  Katrin Rittinger;Philip A. Walker;John F. Eccleston;Kurshid Nurmahomed

  365
  Citations

• The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways

  C. Tarricone;B. Xiao;N. Justin;P. A. Walker

  309
  Citations

• Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer

  Julie A Clapperton;Isaac A Manke;Drew M Lowery;Timmy Ho

  291
  Citations

• A Mitotic Phosphorylation Feedback Network Connects Cdk1, Plk1, 53BP1, and Chk2 to Inactivate the G2/M DNA Damage Checkpoint

  Marcel A. T. M. van Vugt;Alexandra K. Gardino;Rune Linding;Gerard J. Ostheimer

  283
  Citations

• Structural and Functional Versatility of the Fha Domain in DNA-Damage Signaling by the Tumor Suppressor Kinase Chk2

  Jiejin Li;Brandi L. Williams;Lesley F. Haire;Michal Goldberg

  274
  Citations

• STRUCTURAL BASIS OF ASYMMETRY IN THE HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE HETERODIMER

  J Wang;S J Smerdon;J Jäger;L A Kohlstaedt

  262
  Citations