Hideki Sumimoto

Overview

Best Publications

• Structure, regulation and evolution of Nox‐family NADPH oxidases that produce reactive oxygen species

  Hideki Sumimoto

  900
  Citations

• A Novel Superoxide-producing NAD(P)H Oxidase in Kidney

  Akira Shiose;Junya Kuroda;Kazuhiko Tsuruya;Momoki Hirai

  662
  Citations

• Protein Kinase C–Dependent Increase in Reactive Oxygen Species (ROS) Production in Vascular Tissues of Diabetes: Role of Vascular NAD(P)H Oxidase

  Toyoshi Inoguchi;Toshiyo Sonta;Hirotaka Tsubouchi;Takashi Etoh

  599
  Citations

• Novel Human Homologues of p47phox and p67phox Participate in Activation of Superoxide-producing NADPH Oxidases

  Ryu Takeya;Noriko Ueno;Keiichiro Kami;Masahiko Taura

  539
  Citations

• TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy.

  Naoya Onohara;Motohiro Nishida;Ryuji Inoue;Hiroyuki Kobayashi

  461
  Citations

• Molecular composition and regulation of the Nox family NAD(P)H oxidases.

  Hideki Sumimoto;Kei Miyano;Ryu Takeya

  419
  Citations

• Role of Src homology 3 domains in assembly and activation of the phagocyte NADPH oxidase

  Hideki Sumimoto;Youhko Kage;Hiroyuki Nunoi;Hiroyuki Sasaki

  383
  Citations

• Increased expression of NAD(P)H oxidase subunits, NOX4 and p22phox, in the kidney of streptozotocin-induced diabetic rats and its reversibity by interventive insulin treatment

  T. Etoh;T. Inoguchi;M. Kakimoto;N. Sonoda

  355
  Citations

• Tetratricopeptide repeat (TPR) motifs of p67(phox) participate in interaction with the small GTPase Rac and activation of the phagocyte NADPH oxidase

  Hirofumi Koga;Hiroaki Terasawa;Hiroyuki Nunoi;Koichiro Takeshige

  343
  Citations

• Arachidonic acid and phosphorylation synergistically induce a conformational change of p47phox to activate the phagocyte NADPH oxidase.

  Akira Shiose;Hideki Sumimoto

  338
  Citations

• The superoxide-producing NAD(P)H oxidase Nox4 in the nucleus of human vascular endothelial cells

  Junya Kuroda;Kazunori Nakagawa;Tomoko Yamasaki;Kei Ichiro Nakamura

  329
  Citations

• Mechanism for phosphorylation-induced activation of the phagocyte NADPH oxidase protein p47(phox). Triple replacement of serines 303, 304, and 328 with aspartates disrupts the SH3 domain-mediated intramolecular interaction in p47(phox), thereby activating the oxidase.

  Tetsuro Ago;Hiroyuki Nunoi;Takashi Ito;Hideki Sumimoto

  317
  Citations

• Phosphorylation of p47phox directs phox homology domain from SH3 domain toward phosphoinositides, leading to phagocyte NADPH oxidase activation.

  Tetsuro Ago;Futoshi Kuribayashi;Hidekazu Hiroaki;Ryu Takeya

  270
  Citations

• HIV-1 Tat acts as a processivity factor in vitro in conjunction with cellular elongation factors.

  Hiroyuki Kato;Hideki Sumimoto;Philippe Pognonec;Chein Hwa Chen

  264
  Citations

• Involvement of TRPM7 in cell growth as a spontaneously activated Ca2+ entry pathway in human retinoblastoma cells.

  Toyohisa Hanano;Yuji Hara;Juan Shi;Hiromitsu Morita

  263
  Citations

• Assembly and Activation of the Phagocyte NADPH Oxidase SPECIFIC INTERACTION OF THE N-TERMINAL Src HOMOLOGY 3 DOMAIN OF p47phox WITH p22phox IS REQUIRED FOR ACTIVATION OF THE NADPH OXIDASE

  Hideki Sumimoto;Kenichiro Hata;Kazuhito Mizuki;Takashi Ito

  262
  Citations

• Novel modular domain PB1 recognizes PC motif to mediate functional protein–protein interactions

  Takashi Ito;Yasushi Matsui;Tetsuro Ago;Kazuhisa Ota

  256
  Citations

• Phosphoinositide 3-kinase-dependent and -independent activation of the small GTPase Rac2 in human neutrophils.

  Takashi Akasaki;Hirofumi Koga;Hideki Sumimoto

  250
  Citations

• Diverse recognition of non-PxxP peptide ligands by the SH3 domains from p67phox, Grb2 and Pex13p

  Keiichiro Kami;Ryu Takeya;Hideki Sumimoto;Daisuke Kohda

  248
  Citations

• Tetratricopeptide Repeat (TPR) Motifs of p67 phox Participate in Interaction with the Small GTPase Rac and Activation of the

  Hirofumi Koga;Koichiro Takeshige;Hideki Sumimoto

  0
  Citations