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J. David Lambeth

J. David Lambeth

D-Index & Metrics

Biology and Biochemistry

D-Index
85
Citations
35252
World Ranking
3087
National Ranking
1563

Overview

J. David Lambeth is affiliated with Emory University in the United States and conducts research primarily in the fields of Immunology and Microbiology, as well as Biochemistry, Genetics, and Molecular Biology. Their work encompasses key subfields such as Immunology and Molecular Biology.

Their research topics cover areas including immune cell function and interaction, neutrophil, myeloperoxidase and oxidative mechanisms, and genomics, phytochemicals, and oxidative stress. These reflect a focus on cellular immune responses and molecular pathways related to oxidative processes.

Lambeth has contributed to the scientific literature with publications in notable venues such as PLoS ONE. A recent paper titled "Quinazolin-derived myeloperoxidase inhibitor suppresses influenza A virus-induced reactive oxygen species, pro-inflammatory mediators and improves cell survival" was published in 2021 in PLoS ONE. This study addresses the inhibition of myeloperoxidase activity and its effects on reactive oxygen species and inflammatory mediators in the context of influenza A virus infection.

Frequent co-authors in Lambeth's research include Juan A. De La Cruz, Thota Ganesh, Becky A. Diebold, Weiping Cao, and Amelia R. Hofstetter. This network of collaborators contributes to interdisciplinary efforts within the related study areas.

  • Quinazolin-derived myeloperoxidase inhibitor suppresses influenza A virus-induced reactive oxygen species, pro-inflammatory mediators and improves cell survival (2021, PLoS ONE)

  • Juan A. De La Cruz
  • Thota Ganesh
  • Becky A. Diebold
  • Weiping Cao
  • Amelia R. Hofstetter

  • PLoS ONE

  • Immunology and Microbiology
  • Biochemistry, Genetics and Molecular Biology

  • Immunology
  • Molecular Biology

  • Immune Cell Function and Interaction
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Genomics, phytochemicals, and oxidative stress

Best Publications

  • NOX enzymes and the biology of reactive oxygen

    J. David Lambeth

  • Cell transformation by the superoxide-generating oxidase Mox1

    Young Ah Suh;Rebecca S. Arnold;Bernard Lassegue;Jing Shi

  • Novel gp91 phox Homologues in Vascular Smooth Muscle Cells : nox1 Mediates Angiotensin II–Induced Superoxide Formation and Redox-Sensitive Signaling Pathways

    Bernard Lassègue;Dan Sorescu;Katalin Szöcs;QiQin Yin

  • The neutrophil NADPH oxidase

    B.M. Babior;J.D. Lambeth;W. Nauseef

  • Superoxide Production and Expression of Nox Family Proteins in Human Atherosclerosis

    Dan Sorescu;Daiana Weiss;Bernard Lassègue;Roza E. Clempus

  • Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5.

    Guangjie Cheng;Zehong Cao;Xiangxi Xu;Erwin G.Van Meir

  • Nox Enzymes, ROS, and Chronic Disease: An Example of Antagonistic Pleiotropy

    J. David Lambeth

  • Regulation of Nox and Duox Enzymatic Activity and Expression

    J. David Lambeth;Tsukasa Kawahara;Becky Diebold

  • Distinct Subcellular Localizations of Nox1 and Nox4 in Vascular Smooth Muscle Cells

    Lula L. Hilenski;Roza E. Clempus;Mark T. Quinn;J. David Lambeth

  • The NAD(P)H Oxidase Homolog Nox4 Modulates Insulin-Stimulated Generation of H2O2 and Plays an Integral Role in Insulin Signal Transduction

    Kalyankar Mahadev;Hiroyuki Motoshima;Xiangdong Wu;Jean Marie Ruddy

  • The E-loop is involved in hydrogen peroxide formation by the NADPH oxidase Nox4.

    Ina Takac;Katrin Schröder;Leilei Zhang;Bernard Lardy

  • Hydrogen peroxide mediates the cell growth and transformation caused by the mitogenic oxidase Nox1

    Rebecca S. Arnold;Jing Shi;Emma Murad;Anne M. Whalen

  • Reactive oxygen generated by Nox1 triggers the angiogenic switch

    Jack L. Arbiser;John Petros;Robert Klafter;Baskaran Govindajaran

  • Upregulation of Nox-based NAD(P)H oxidases in restenosis after carotid injury.

    Katalin Szöcs;Bernard Lassègue;Dan Sorescu;Lula L Hilenski

  • Novel homologs of gp91phox.

    J.David Lambeth;Guangjie Cheng;Rebecca S Arnold;William A Edens

  • NOX1 OVEREXPRESSION POTENTIATES ANGIOTENSIN II-INDUCED HYPERTENSION AND VASCULAR SMOOTH MUSCLE HYPERTROPHY IN TRANSGENIC MICE

    Anna Dikalova;Roza Clempus;Bernard Lassègue;Guangjie Cheng

  • Nox Enzymes and New Thinking on Reactive Oxygen: A Double-Edged Sword Revisited

    J. David Lambeth;Andrew S. Neish

  • Cyclophilin A Is a Secreted Growth Factor Induced by Oxidative Stress

    Zheng-Gen Jin;Matthew G. Melaragno;Duan-Fang Liao;Chen Yan

  • Contrasting Roles of NADPH Oxidase Isoforms in Pressure-Overload Versus Angiotensin II–Induced Cardiac Hypertrophy

    Jonathan A. Byrne;David J. Grieve;Jennifer K. Bendall;Jian-Mei Li

  • Tyrosine cross-linking of extracellular matrix is catalyzed by Duox, a multidomain oxidase/peroxidase with homology to the phagocyte oxidase subunit gp91phox.

    William A. Edens;Lisa Sharling;Guangjie Cheng;Raymond Shapira

Frequent Co-Authors

Kathy K. Griendling
Kathy K. Griendling Emory University
Mark T. Quinn
Mark T. Quinn Montana State University
Jae Ho Kim
Jae Ho Kim Pusan National University
Sung Ho Ryu
Sung Ho Ryu Pohang University of Science and Technology
Karl-Heinz Krause
Karl-Heinz Krause University of Geneva
Jacqueline M. Katz
Jacqueline M. Katz Emory University
Pann-Ghill Suh
Pann-Ghill Suh Korea Brain Research Institute
Jacek Zielonka
Jacek Zielonka Medical College of Wisconsin
Victor J. Thannickal
Victor J. Thannickal Tulane University
Andrew S. Neish
Andrew S. Neish Emory University

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