D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 86 Citations 24,023 237 World Ranking 1932 National Ranking 1082

Research.com Recognitions

Awards & Achievements

2014 - Fellow of the American Association for the Advancement of Science (AAAS)

Member of the Association of American Physicians

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Immune system

His primary areas of study are NADPH oxidase, Molecular biology, Chronic granulomatous disease, Biochemistry and Oxidase test. He has included themes like Respiratory burst and Superoxide in his NADPH oxidase study. Mary C. Dinauer works mostly in the field of Superoxide, limiting it down to concerns involving Nitric oxide and, occasionally, Superoxide dismutase and Peroxynitrite.

The Molecular biology study combines topics in areas such as Complementary DNA, Gene and Mutant. His research on Chronic granulomatous disease concerns the broader Immunology. His Oxidase test research includes elements of Phagocyte and Potassium channel.

His most cited work include:

  • Mouse model of X-linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production (779 citations)
  • Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases (627 citations)
  • Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense. (526 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in NADPH oxidase, Immunology, Chronic granulomatous disease, Molecular biology and Oxidase test. His NADPH oxidase research is multidisciplinary, relying on both Respiratory burst and Superoxide. His Immunology research integrates issues from Haematopoiesis, Stem cell and Transplantation.

His Chronic granulomatous disease research is multidisciplinary, incorporating perspectives in Aspergillus fumigatus, Phagocyte, CYBB and Genetic enhancement, Gene. His research integrates issues of Mutation, Cytochrome, Mutant and Transfection in his study of Molecular biology. His work deals with themes such as Phagosome and COS cells, which intersect with Oxidase test.

He most often published in these fields:

  • NADPH oxidase (55.47%)
  • Immunology (34.77%)
  • Chronic granulomatous disease (32.42%)

What were the highlights of his more recent work (between 2010-2021)?

  • NADPH oxidase (55.47%)
  • Immunology (34.77%)
  • Chronic granulomatous disease (32.42%)

In recent papers he was focusing on the following fields of study:

His main research concerns NADPH oxidase, Immunology, Chronic granulomatous disease, Inflammation and Oxidase test. His research in NADPH oxidase intersects with topics in Molecular biology, Macrophage and Superoxide. His work carried out in the field of Superoxide brings together such families of science as Respiratory burst, Extracellular and Siderophore.

His studies in Immunology integrate themes in fields like Systemic lupus erythematosus and Haematopoiesis. His Chronic granulomatous disease study integrates concerns from other disciplines, such as CYBB, Immune system, Myeloperoxidase and Granulocyte. His Oxidase test research includes elements of Zymosan, Reactive oxygen species, Epitope and Antigen presentation.

Between 2010 and 2021, his most popular works were:

  • Germline CYBB mutations that selectively affect macrophages in kindreds with X-linked predisposition to tuberculous mycobacterial disease (199 citations)
  • Autophagy proteins control goblet cell function by potentiating reactive oxygen species production (147 citations)
  • Gene therapy of chronic granulomatous disease: the engraftment dilemma. (124 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Immune system

Mary C. Dinauer mainly focuses on Immunology, NADPH oxidase, Innate immune system, Respiratory burst and Chronic granulomatous disease. His Immunology research incorporates themes from Haematopoiesis, Streptococcus pneumoniae, Progenitor cell, Microbiology and Bacterial pneumonia. His NADPH oxidase research is classified as research in Cell biology.

His Cell biology research is multidisciplinary, relying on both Oxidase test and Biochemistry. Within one scientific family, he focuses on topics pertaining to Superoxide under Respiratory burst, and may sometimes address concerns connected to Phagosome, Chloride channel, Reactive oxygen species and Siderophore. His Chronic granulomatous disease research incorporates elements of Chédiak–Higashi syndrome, Chemotaxis, Hyperimmunoglobulin E syndrome and Myeloperoxidase.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Mouse model of X-linked chronic granulomatous disease, an inherited defect in phagocyte superoxide production

Jonathan D. Pollock;David A. Williams;David A. Williams;Mary A.C. Gifford;Ling Lin Li.
Nature Genetics (1995)

986 Citations

Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases

Kendra D. Martyn;Linda M. Frederick;Katharina von Loehneysen;Mary C. Dinauer.
Cellular Signalling (2006)

797 Citations

Salmonella pathogenicity island 2-dependent evasion of the phagocyte NADPH oxidase.

Andrés Vazquez-Torres;Yisheng Xu;Jessica Jones-Carson;David W. Holden.
Science (2000)

696 Citations

Phenotype of mice and macrophages deficient in both phagocyte oxidase and inducible nitric oxide synthase.

Michael U Shiloh;John D MacMicking;Susan Nicholson;Juliet E Brause.
Immunity (1999)

635 Citations

Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense.

Andrew W. Roberts;Chaekyun Kim;Ling Zhen;John B. Lowe.
Immunity (1999)

634 Citations

Activation of antibacterial autophagy by NADPH oxidases

Ju Huang;Veronica Canadien;Grace Y. Lam;Benjamin E. Steinberg.
Proceedings of the National Academy of Sciences of the United States of America (2009)

569 Citations

Absence of Respiratory Burst in X-linked Chronic Granulomatous Disease Mice Leads to Abnormalities in Both Host Defense and Inflammatory Response to Aspergillus fumigatus

David E. Morgenstern;Mary A.C. Gifford;Ling Lin Li;Claire M. Doerschuk.
Journal of Experimental Medicine (1997)

503 Citations

The glycoprotein encoded by the X-linked chronic granulomatous disease locus is a component of the neutrophil cytochrome b complex

Mary C. Dinauer;Stuart H. Orkin;Stuart H. Orkin;Robin Brown;Robin Brown;Algirdas J. Jesaitis.
Nature (1987)

499 Citations

Periplasmic superoxide dismutase protects Salmonella from products of phagocyte NADPH-oxidase and nitric oxide synthase

Mary Ann De Groote;Urs A. Ochsner;Michael U. Shiloh;Carl Nathan.
Proceedings of the National Academy of Sciences of the United States of America (1997)

488 Citations

Ischemic Stroke Injury Is Reduced in Mice Lacking a Functional NADPH Oxidase

Claire E. Walder;Simon P. Green;Walter C. Darbonne;Joanne Mathias.
Stroke (1997)

483 Citations

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