What is he best known for?
The fields of study he is best known for:
- Gene
- Internal medicine
- Immune system
Harry L. Malech mainly focuses on Chronic granulomatous disease, Immunology, Molecular biology, NADPH oxidase and Superoxide.
His Chronic granulomatous disease study combines topics in areas such as Hematopoietic stem cell transplantation, Antibiotics, Microbiology and Internal medicine, Chemotherapy.
The concepts of his Immunology study are interwoven with issues in Genetic enhancement, Transplantation and In vivo.
The various areas that Harry L. Malech examines in his Molecular biology study include Neutrophil extracellular traps, Mitochondrial ROS, Complementary DNA, Lupus erythematosus and Proinflammatory cytokine.
His work carried out in the field of NADPH oxidase brings together such families of science as Oxidase test, Disease, Pathology and Induced pluripotent stem cell.
His Superoxide research includes elements of Missense mutation, Phagocyte, Cytosol, CYBB and Gene.
His most cited work include:
- Chronic granulomatous disease. Report on a national registry of 368 patients. (1383 citations)
- STAT3 Mutations in the Hyper-IgE Syndrome (894 citations)
- Current concepts: immunology; neutrophils in human diseases (776 citations)
What are the main themes of his work throughout his whole career to date?
His main research concerns Immunology, Chronic granulomatous disease, Molecular biology, Genetic enhancement and Stem cell.
His Immunology research is multidisciplinary, incorporating elements of Hematopoietic stem cell transplantation, Transplantation, Hematopoietic stem cell and Severe combined immunodeficiency.
The Chronic granulomatous disease study combines topics in areas such as NADPH oxidase, Surgery and Internal medicine, Disease, Pathology.
His NADPH oxidase research incorporates themes from Phagocyte and Superoxide.
His work deals with themes such as Cell culture and Biochemistry, Gene, Transgene, Exon, which intersect with Molecular biology.
Harry L. Malech works mostly in the field of Stem cell, limiting it down to topics relating to Bone marrow and, in certain cases, CXCR4, as a part of the same area of interest.
He most often published in these fields:
- Immunology (45.32%)
- Chronic granulomatous disease (35.49%)
- Molecular biology (23.02%)
What were the highlights of his more recent work (between 2017-2021)?
- Chronic granulomatous disease (35.49%)
- Immunology (45.32%)
- Genetic enhancement (18.94%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Chronic granulomatous disease, Immunology, Genetic enhancement, Internal medicine and Hematopoietic stem cell transplantation.
His Chronic granulomatous disease research integrates issues from NADPH oxidase, Colitis and Primary immunodeficiency, Disease, Inflammatory bowel disease.
Immunology is closely attributed to Allele in his work.
His Genetic enhancement research is multidisciplinary, relying on both Progenitor cell, Haematopoiesis and Immunity.
His Internal medicine study integrates concerns from other disciplines, such as Gastroenterology and Oncology.
His Hematopoietic stem cell transplantation research incorporates elements of Interferon γ, Immune system, Severe combined immunodeficiency and Antigen.
Between 2017 and 2021, his most popular works were:
- Lentiviral Gene Therapy Combined with Low-Dose Busulfan in Infants with SCID-X1. (88 citations)
- X-linked carriers of chronic granulomatous disease: Illness, lyonization, and stability. (78 citations)
- Gene correction for SCID-X1 in long-term hematopoietic stem cells. (69 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Internal medicine
- Immune system
Harry L. Malech spends much of his time researching Haematopoiesis, Hematopoietic stem cell transplantation, Immunology, Chronic granulomatous disease and Genetic enhancement.
Harry L. Malech combines subjects such as Myeloid, Cancer research, CD34 and Bone marrow with his study of Haematopoiesis.
His Hematopoietic stem cell transplantation study combines topics from a wide range of disciplines, such as Inflammatory bowel disease, Treatment outcome, Severe combined immunodeficiency and Allogeneic hct.
His Immunology research includes themes of Candida albicans, Allele and CD38.
His research integrates issues of Inflammatory Bowel Diseases, Odds ratio and Pediatrics in his study of Chronic granulomatous disease.
His research in Genetic enhancement intersects with topics in Progenitor cell, Immunity and Intensive care medicine.
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