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D-Index & Metrics

Biology and Biochemistry

D-Index
57
Citations
18315
World Ranking
13567
National Ranking
5752

Overview

Douglas C. Dean is affiliated with the University of Louisville in the United States. Their research spans multiple fields, primarily concentrating on Medicine and Biochemistry, Genetics and Molecular Biology.

Within these broader fields, their work focuses on several subfields, including Molecular Biology, Radiology, Nuclear Medicine and Imaging, Cellular and Molecular Neuroscience, Cognitive Neuroscience, and Cell Biology.

Their main researched topics include:

  • Retinal Development and Disorders
  • Corneal Surgery and Treatments
  • Hippo pathway signaling and YAP/TAZ
  • Photoreceptor and optogenetics research
  • Corneal surgery and disorders
  • Neuroscience and Neuropharmacology Research
  • Advanced Neuroimaging Techniques and Applications

Douglas C. Dean has published extensively, contributing articles to journals such as:

  • Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
  • Cell Reports
  • Science Advances
  • iScience
  • Communications Biology

Some recent papers authored or co-authored by Dean include:

  • "Zeb1 induces immune checkpoints to form an immunosuppressive envelope around invading cancer cells," 2021, Science Advances
  • "Spheroid-induced heterogeneity and plasticity of uveal melanoma cells," 2022, Cellular Oncology
  • "Zeb1 regulation of wound-healing-induced inflammation in alkali-damaged corneas," 2022, iScience
  • "Zeb1 promotes corneal neovascularization by regulation of vascular endothelial cell proliferation," 2020, Communications Biology
  • "Expression and Function of ZEB1 in the Cornea," 2021, Cells

Frequent collaborators include:

  • Yongqing Liu
  • Xiaoqin Lu
  • Henry J. Kaplan
  • Yao Chen
  • Douglas Emery

Best Publications

  • The Rb/E2F pathway: expanding roles and emerging paradigms

    J. William Harbour;Douglas C. Dean

  • Rb Interacts with Histone Deacetylase to Repress Transcription

    Robin X Luo;Antonio A Postigo;Douglas C Dean

  • Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

    J.William Harbour;Robin X Luo;Angeline Dei Santi;Antonio A Postigo

  • Retinoblastoma protein switches the E2F site from positive to negative element.

    Steven J. Weintraub;Cheryl A. Prater;Douglas C. Dean

  • Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF.

    H.Steven Zhang;Mark Gavin;Anjali Dahiya;Antonio A Postigo

  • Mechanism of active transcriptional repression by the retinoblastoma protein

    Steven J. Weintraub;Kevin N. B. Chow;Robin X. Luo;Steven H. Zhang

  • Rb function in cell-cycle regulation and apoptosis

    J. William Harbour;Douglas C. Dean

  • Characterization of the promoter for vascular cell adhesion molecule-1 (VCAM-1).

    M.F. Iademarco;J.J. McQuillan;G.D. Rosen;D.C. Dean

  • EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness.

    Ester Sánchez-Tilló;Yongqing Liu;Oriol de Barrios;Laura Siles

  • Roles for the integrin VLA-4 and its counter receptor VCAM-1 in myogenesis

    Glenn D. Rosen;Joshua R. Sanes;Rhonda LaChance;Jeanette M. Cunningham

  • Active Transcriptional Repression by the Rb–E2F Complex Mediates G1 Arrest Triggered by p16INK4a, TGFβ, and Contact Inhibition

    H.Steven Zhang;Antonio A Postigo;Douglas C Dean

  • ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1

    Peijing Zhang;Yongkun Wei;L. i. Wang;Bisrat G. Debeb

  • Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin

    Susana Gonzalo;Marta García-Cao;Mario F. Fraga;Gunnar Schotta

  • ZEB represses transcription through interaction with the corepressor CtBP.

    Antonio A. Postigo;Douglas C. Dean

  • ZEB1 Links Epithelial-Mesenchymal Transition and Cellular Senescence

    Yongqing Liu;Shahenda El-Naggar;Douglas S. Darling;Yujiro Higashi

  • Regulation of vascular cell adhesion molecule-1 expression by IL-4 and TNF-alpha in cultured endothelial cells.

    M F Iademarco;J L Barks;D C Dean

  • Linking the Rb and polycomb pathways.

    Anjali Dahiya;Sharon Wong;Susana Gonzalo;Mark Gavin

  • Control of Glutamine Metabolism By the Tumor Suppressor Rb

    Miriam R. Reynolds;Andrew N. Lane;Brian Robertson;Sharen Kemp

  • Role of the LXCXE Binding Site in Rb Function

    Anjali Dahiya;Mark R. Gavin;Robin X. Luo;Douglas C. Dean

  • ZEB, a vertebrate homolog of Drosophila Zfh-1, is a negative regulator of muscle differentiation

    Antonio A. Postigo;Douglas C. Dean

Frequent Co-Authors

Henry J. Kaplan
Henry J. Kaplan University of Louisville
Jason Chesney
Jason Chesney University of Louisville
Glenn D. Rosen
Glenn D. Rosen Beth Israel Deaconess Medical Center
Mariusz Z. Ratajczak
Mariusz Z. Ratajczak University of Louisville
Wendy A. Woodward
Wendy A. Woodward The University of Texas MD Anderson Cancer Center
K. Kian Ang
K. Kian Ang The University of Texas MD Anderson Cancer Center
Han Liang
Han Liang The University of Texas MD Anderson Cancer Center
Ewa K. Zuba-Surma
Ewa K. Zuba-Surma Jagiellonian University
Maria A. Blasco
Maria A. Blasco Spanish National Cancer Research Centre
Antoni Castells
Antoni Castells University of Barcelona

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