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Biology and Biochemistry

D-Index
72
Citations
26259
World Ranking
6155
National Ranking
180

Overview

Alain Puisieux is affiliated with Claude Bernard University Lyon 1 in France. Their research spans primarily the fields of Biochemistry, Genetics and Molecular Biology, with a significant presence in Medicine. The main areas of focus include Molecular Biology, Oncology, Cancer Research, Immunology, and Cell Biology.

The scientist's work addresses several key topics within these fields, including:

  • Cancer Cells and Metastasis
  • RNA modifications and cancer
  • Cancer Genomics and Diagnostics
  • RNA Research and Splicing
  • Epigenetics and DNA Methylation
  • Immune cells in cancer
  • Cancer-related molecular mechanisms research

Alain Puisieux has contributed to multiple recent publications, notable among them are:

  • Guidelines and definitions for research on epithelial-mesenchymal transition, 2020, Nature Reviews Molecular Cell Biology
  • A druggable copper-signalling pathway that drives inflammation, 2023, Nature
  • Comprehensive characterization of claudin-low breast tumors reflects the impact of the cell-of-origin on cancer evolution, 2020, Nature Communications
  • ZEB1 transcription factor promotes immune escape in melanoma, 2022, Journal for ImmunoTherapy of Cancer
  • Ribosomal RNA 2'O-methylation as a novel layer of inter-tumour heterogeneity in breast cancer, 2020, NAR Cancer

The scientist frequently publishes in journals such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • NAR Cancer
  • Nature Reviews Molecular Cell Biology
  • Cancers
  • iScience

Collaboration forms a significant aspect of their work, with frequent coauthors including Laurie Tonon, Roxane M. Pommier, Maria Ouzounova, Anne-Pierre Morel, and Frédérique Fauvet.

Best Publications

  • Metastasis: a question of life or death

    Patrick Mehlen;Alain Puisieux

  • Generation of breast cancer stem cells through epithelial-mesenchymal transition.

    Anne-Pierre Morel;Marjory Lièvre;Clémence Thomas;George W. Hinkal

  • Guidelines and definitions for research on epithelial–mesenchymal transition

    Jing Yang;Parker Antin;Geert Berx;Cédric Blanpain

  • Oncogenic roles of EMT-inducing transcription factors.

    Alain Puisieux;Thomas Brabletz;Julie Caramel

  • Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma

    Isabelle Janoueix-Lerosey;Delphine Lequin;Delphine Lequin;Laurence Brugières;Agnès Ribeiro

  • Induction of EMT by Twist Proteins as a Collateral Effect of Tumor-Promoting Inactivation of Premature Senescence

    Stéphane Ansieau;Jeremy Bastid;Jeremy Bastid;Agnès Doreau;Anne Pierre Morel

  • Regulatory T Cells Recruited through CCL22/CCR4 Are Selectively Activated in Lymphoid Infiltrates Surrounding Primary Breast Tumors and Lead to an Adverse Clinical Outcome

    Michael Gobert;Isabelle Treilleux;Nathalie Bendriss-Vermare;Thomas Bachelot

  • p53 mutation in hepatocellular carcinoma after aflatoxin exposure

    Brigitte Bressac;Alain Puisieux;Michael Kew;Martin Volkmann

  • Interleukin 17 acts in synergy with B cell-activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus.

    Agnès Doreau;Alexandre Belot;Alexandre Belot;Jérémy Bastid;Jérémy Bastid;Benjamin Riche

  • A switch in the expression of embryonic EMT-inducers drives the development of malignant melanoma.

    Julie Caramel;Eftychios Papadogeorgakis;Louise Hill;Gareth J. Browne

  • Identification of BTG2, an antiproliferative p53–dependent component of the DNA damage cellular response pathway

    Jean-Pierre Rouault;Nicole Falette;Fabienne Guéhenneux;Céline Guillot

  • Real-time PCR based on SYBR-Green I fluorescence: An alternative to the TaqMan assay for a relative quantification of gene rearrangements, gene amplifications and micro gene deletions

    Frederique Ponchel;Carmel Toomes;Kieran Bransfield;Fong T Leong

  • Selective targeting of p53 gene mutational hotspots in human cancers by etiologically defined carcinogens.

    Alain Puisieux;Susan Lim;John Groopman;Mehmet Ozturk

  • Impaired IFN-α production by plasmacytoid dendritic cells favors regulatory T-cell expansion that may contribute to breast cancer progression.

    Vanja Sisirak;Julien Faget;Michael Gobert;Nadège Goutagny

  • Oncogenic cooperation between H-Twist and N-Myc overrides failsafe programs in cancer cells

    Sandrine Valsesia-Wittmann;Maud Magdeleine;Sébastien Dupasquier;Elisabeth Garin

  • Pleiotropic Roles for ZEB1 in Cancer

    Julie Caramel;Julie Caramel;Maud Ligier;Maud Ligier;Alain Puisieux;Alain Puisieux

  • Neurofibromatosis and early onset of cancers in hMLH1-deficient children

    Qing Wang;Christine Lasset;Françoise Desseigne;Didier Frappaz

  • p53 Acts as a Safeguard of Translational Control by Regulating Fibrillarin and rRNA Methylation in Cancer

    Virginie Marcel;Virginie Marcel;Sandra E. Ghayad;Sandra E. Ghayad;Stéphane Belin;Stéphane Belin;Gabriel Therizols;Gabriel Therizols

  • A twist for survival and cancer progression.

    A Puisieux;S Valsesia-Wittmann;S Ansieau

  • Detection of exon deletions and duplications of the mismatch repair genes in hereditary nonpolyposis colorectal cancer families using multiplex polymerase chain reaction of short fluorescent fragments.

    Françoise Charbonnier;Grégory Raux;Qing Wang;Nathalie Drouot

Frequent Co-Authors

Mehmet Ozturk
Mehmet Ozturk Izmir Biomedicine and Genome Center
Christophe Caux
Christophe Caux Cancer Center of Lyon
Jean-Yves Blay
Jean-Yves Blay Claude Bernard University Lyon 1
Patrick Mehlen
Patrick Mehlen UniCancer Group
Dominique Bellet
Dominique Bellet Institute Curie
Pierre Laurent-Puig
Pierre Laurent-Puig Université Paris Cité
Lionel Larue
Lionel Larue University of Paris-Saclay
Eric Gilson
Eric Gilson Université Côte d'Azur
Thierry Frebourg
Thierry Frebourg Grenoble Alpes University
Olivier Delattre
Olivier Delattre PSL University

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