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Christophe Caux

Christophe Caux

D-Index & Metrics

Immunology

D-Index
95
Citations
46753
World Ranking
877
National Ranking
28

Overview

Christophe Caux is affiliated with Grenoble Alpes University in France. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with a significant focus on immunology and oncology, accompanied by molecular biology, pulmonary and respiratory medicine, and obstetrics and gynecology as subfields.

The main topics of Christophe Caux's research work include:

  • Cancer Immunotherapy and Biomarkers
  • Immunotherapy and Immune Responses
  • Immune cells in cancer
  • T-cell and B-cell Immunology
  • Immune Cell Function and Interaction
  • CAR-T cell therapy research
  • Ovarian cancer diagnosis and treatment

They have been involved in frequent publications within several venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Bulletin du Cancer
  • Cancer Immunology Research
  • Cancer Research
  • Cancers

Christophe Caux has collaborated extensively with several co-authors, notably:

  • Bertrand Dubois
  • Nathalie Bendriss-Vermare
  • Justine Berthet
  • Isabelle Treilleux
  • Jenny Valladeau-Guilemond

The following is a selection of recent papers authored by Christophe Caux:

  • "Durable and controlled depletion of neutrophils in mice," 2020, Nature Communications
  • "IFN-III is selectively produced by cDC1 and predicts good clinical outcome in breast cancer," 2020, Science Immunology
  • "Recruitment and Expansion of Tregs Cells in the Tumor Environment-How to Target Them?" 2021, Cancers
  • "ZEB1 transcription factor promotes immune escape in melanoma," 2022, Journal for ImmunoTherapy of Cancer
  • "Identification of shared tumor epitopes from endogenous retroviruses inducing high-avidity cytotoxic T cells for cancer immunotherapy," 2022, Science Advances

Best Publications

  • Immunobiology of Dendritic Cells

    Jacques Banchereau;Francine Briere;Christophe Caux;Jean Davoust

  • Selective Recruitment of Immature and Mature Dendritic Cells by Distinct Chemokines Expressed in Different Anatomic Sites

    Marie-Caroline Dieu;Béatrice Vanbervliet;Alain Vicari;Jean-Michel Bridon

  • GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cells

    C. Caux;C. Dezutter-Dambuyant;D. Schmitt;J. Banchereau

  • Activation of human dendritic cells through CD40 cross-linking.

    C Caux;C Massacrier;B Vanbervliet;B Dubois

  • CD34+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF+TNF alpha.

    C Caux;B Vanbervliet;C Massacrier;C Dezutter-Dambuyant

  • Langerin, a Novel C-Type Lectin Specific to Langerhans Cells, Is an Endocytic Receptor that Induces the Formation of Birbeck Granules

    Jenny Valladeau;Odile Ravel;Colette Dezutter-Dambuyant;Kevin Moore

  • Cold Tumors: A Therapeutic Challenge for Immunotherapy.

    Paola Bonaventura;Tala Shekarian;Vincent Alcazer;Jenny Valladeau-Guilemond

  • Regulatory T Cells Recruited through CCL22/CCR4 Are Selectively Activated in Lymphoid Infiltrates Surrounding Primary Breast Tumors and Lead to an Adverse Clinical Outcome

    Michael Gobert;Isabelle Treilleux;Nathalie Bendriss-Vermare;Thomas Bachelot

  • A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells.

    Gregory Gautier;Martine Humbert;Florence Deauvieau;Mathieu Scuiller

  • Inhibition of the Differentiation of Dendritic Cells From CD34+ Progenitors by Tumor Cells: Role of Interleukin-6 and Macrophage Colony-Stimulating Factor

    C. Menetrier-Caux;G. Montmain;G. Montmain;M.C. Dieu;M.C. Dieu;C. Bain;C. Bain

  • Up-Regulation of Macrophage Inflammatory Protein-3α/CCL20 and CC Chemokine Receptor 6 in Psoriasis

    Bernhard Homey;Marie-Caroline Dieu-Nosjean;Andrea Wiesenborn;Catherine Massacrier

  • CD34+ Hematopoietic Progenitors From Human Cord Blood Differentiate Along Two Independent Dendritic Cell Pathways in Response to Granulocyte-Macrophage Colony-Stimulating Factor Plus Tumor Necrosis Factor α: II. Functional Analysis

    Christophe Caux;Catherine Massacrier;Béatrice Vanbervliet;Bertrand Dubois

  • TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway

    Sébastien Viel;Antoine Marçais;Fernando Souza Fonseca Guimaraes;Fernando Souza Fonseca Guimaraes;Roisin Loftus

  • The Cytokine Profile Expressed by Human Dendritic Cells Is Dependent on Cell Subtype and Mode of Activation

    de Saint-Vis B;Fugier-Vivier I;Massacrier C;Gaillard C

  • A Novel Lysosome-Associated Membrane Glycoprotein, DC-LAMP, Induced upon DC Maturation, Is Transiently Expressed in MHC Class II Compartment

    B de Saint-Vis;J Vincent;S Vandenabeele;B Vanbervliet

  • Chemokines in cancer.

    Alain P Vicari;Christophe Caux

  • Macrophage Inflammatory Protein 3α Is Expressed at Inflamed Epithelial Surfaces and Is the Most Potent Chemokine Known in Attracting Langerhans Cell Precursors

    Marie-Caroline Dieu-Nosjean;Catherine Massacrier;Bernhard Homey;Béatrice Vanbervliet

  • Dendritic cells rapidly recruited into epithelial tissues via CCR6/CCL20 are responsible for CD8+ T cell crosspriming in vivo.

    Marie Le Borgne;Marie Le Borgne;Nathalie Etchart;Nathalie Etchart;Anne Goubier;Anne Goubier;Sergio A. Lira

  • B70/B7-2 is identical to CD86 and is the major functional ligand for CD28 expressed on human dendritic cells.

    C Caux;B Vanbervliet;C Massacrier;M Azuma

  • Reversal of Tumor-induced Dendritic Cell Paralysis by CpG Immunostimulatory Oligonucleotide and Anti–Interleukin 10 Receptor Antibody

    Alain P. Vicari;Claudia Chiodoni;Céline Vaure;Smina Aït-Yahia

Frequent Co-Authors

Jean-Yves Blay
Jean-Yves Blay Claude Bernard University Lyon 1
Francine Brière
Francine Brière Baylor Scott & White Health
Serge Lebecque
Serge Lebecque Claude Bernard University Lyon 1
Sem Saeland
Sem Saeland Schering-Plough
Giorgio Trinchieri
Giorgio Trinchieri National Institutes of Health
Isabelle Ray-Coquard
Isabelle Ray-Coquard Claude Bernard University Lyon 1
Albert Zlotnik
Albert Zlotnik University of California, Irvine
Daniel Schmitt
Daniel Schmitt Grenoble Alpes University
Aurélien Marabelle
Aurélien Marabelle Institut Gustave Roussy

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